sSgo1, a Guardian of Centriole Cohesion.
March 16th, 2008 | by admin |sSgo1, a Guardian of Centriole Cohesion.
Sgo1 plays a key role in protecting sister chromatid cohesion during mitosis. In this issue of Developmental Cell, Wang et al. describe a shorter splice variant of Sgo1 (sSgo1) that functions specifically in centriole cohesion. sSgo1 may be the \”glue\” that holds paired centrioles together in an engaged state before their disengagement in late mitosis.
Tsang WY, Dynlacht BD.
Department of Pathology and Cancer Institute, New York University School of Medicine, 522 1(st) Avenue, New York, NY 10016, USA.