Medical and Biomedical Researches

Guided saccades modulate face- and body-sensitive activation in the occipitotemporal cortex during s

March 19th, 2008
Guided saccades modulate face- and body-sensitive activation in the occipitotemporal cortex during social perception. Functional magnetic resonance imaging (fMRI) has identified distinct brain regions in ventral occipitotemporal cortex (VOTC) and lateral occipitotemporal cortex (LOTC) that are differentially activated by pictures of faces and bodies. Recent work ...

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Microstructural integrity of the corpus callosum linked with neuropsychological performance in adole

March 19th, 2008
Microstructural integrity of the corpus callosum linked with neuropsychological performance in adolescents. Background: Diffusion tensor imaging (DTI) has revealed microstructural aspects of adolescent brain development, the cognitive correlates of which remain relatively uncharacterized. Methods: DTI was used to assess white matter microstructure in 18 typically developing ...

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Mutagenicity assessment of acrylate and methacrylate compounds and implications for regulatory toxic

March 19th, 2008
Mutagenicity assessment of acrylate and methacrylate compounds and implications for regulatory toxicology requirements. Esters of acrylic acid and methacrylic acid, more commonly known as acrylates and methacrylates, respectively, are key raw materials in the coatings and printing industry, with several of its chemical class used in ...

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Accumulation of selenium in aquatic systems downstream of a uranium mining operation in northern Sas

March 19th, 2008
Accumulation of selenium in aquatic systems downstream of a uranium mining operation in northern Saskatchewan, Canada. The objective of this study was to investigate the accumulation of selenium in lakes downstream of a uranium mine operation in northern Saskatchewan, Canada. Selenium concentrations in sediment and biota ...

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Mechanical factors relate to pain in knee osteoarthritis.

March 19th, 2008
Mechanical factors relate to pain in knee osteoarthritis. BACKGROUND: Pain experienced by people with knee osteoarthritis is related to psychosocial factors and damage to articular tissues and/or the pain pathway itself. Mechanical factors have been speculated to trigger this pain experience; yet mechanics have not been ...

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Midwives and nurses awareness of patients’ rights.

March 19th, 2008
Midwives and nurses awareness of patients\' rights. AIM: to determine the level of awareness of patients\' rights among midwives and nurses working in the third and fourth largest cities in Turkey. METHODS: cross-sectional descriptive survey conducted among participants working in university hospitals, state hospitals and village ...

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Meige syndrome: A rare form of cranial dystonia that was treated successfully with botulinum toxin.

March 19th, 2008
Meige syndrome: A rare form of cranial dystonia that was treated successfully with botulinum toxin. Meige syndrome, a rare form of cranial dystonia, is characterised by bilateral involuntary activity of facial and perioral muscles combined with blepharospasms. A case of a 15-year-old boy with Meige syndrome ...

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A vaccine prepared from a non-pathogenic H7N7 virus isolated from natural reservoir conferred protec

March 19th, 2008
A vaccine prepared from a non-pathogenic H7N7 virus isolated from natural reservoir conferred protective immunity against the challenge with lethal dose of highly pathogenic avian influenza virus in chickens. During 2001-2004, 41 H7 influenza viruses (2 H7N1 and 39 H7N7 strains) were isolated from fecal samples ...

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Induction of neutralising antibodies and cellular immune responses against SARS coronavirus by recom

March 19th, 2008
Induction of neutralising antibodies and cellular immune responses against SARS coronavirus by recombinant measles viruses. Live attenuated recombinant measles viruses (rMV) expressing a codon-optimised spike glycoprotein (S) or nucleocapsid protein (N) of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) were generated (rMV-S and rMV-N). Both recombinant viruses ...

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3D and quantum QSAR of non-benzodiazepine compounds.

March 19th, 2008
3D and quantum QSAR of non-benzodiazepine compounds. A combined physicochemical and 3D technique is used to establish the QSAR of four series of non-benzodiazepines towards BzR. In physicochemical QSAR study, the semi-empirical PM3 based parameters like hardness, electronegativity, electrophilicity index, molar refractivity, heat of formation, solvent ...

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Clinical severity of Alzheimer’s disease is associated with PIB uptake in PET.

March 19th, 2008
Clinical severity of Alzheimer\'s disease is associated with PIB uptake in PET. BACKGROUND: The positron emission tomography (PET) tracer [11C]-Pittsburgh Compound-B ([11C]PIB) allows the in vivo assessment of amyloid plaque burden in the brain. In a cross-sectional study we examined the association between the severity of ...

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A meta-analysis of hippocampal atrophy rates in Alzheimer’s disease.

March 19th, 2008
A meta-analysis of hippocampal atrophy rates in Alzheimer\'s disease. Hippocampal atrophy rates are useful in both diagnosing and tracking Alzheimer\'s disease (AD). However, cohorts and methods used to determine such rates are heterogeneous, leading to differences in reported annualised rates. We performed a meta-analysis of hippocampal ...

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Increases in cholinergic neurotransmission measured by using choline-sensitive microelectrodes: Enha

March 19th, 2008
Increases in cholinergic neurotransmission measured by using choline-sensitive microelectrodes: Enhanced detection by hydrolysis of acetylcholine on recording sites? Previous experiments demonstrated that second-based transient increases in choline concentrations measured by electrodes coated with choline oxidase (ChOx) and the amperometric detection of hydrogen peroxide validly indicate the ...

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Effects of ghrelin on neuronal activity in the ventromedial nucleus of the hypothalamus in infantile

March 19th, 2008
Effects of ghrelin on neuronal activity in the ventromedial nucleus of the hypothalamus in infantile rats: An in vitro study. Ghrelin is an endogenous ligand for the growth hormone (GH) secretagogue (GHS) receptor (GHS-R) and a potent stimulant for GH secretion even in infantile rats before ...

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Central and peripheral administration of amylin induces energy expenditure in anesthetized rats.

March 19th, 2008
Central and peripheral administration of amylin induces energy expenditure in anesthetized rats. Amylin is a peptide hormone that is co-released with insulin from pancreatic beta-cells following a meal. Intracerebroventricular (icv) administration of amylin (1-100pmol), or an amylin agonist, salmon calcitonin, elicited dose-dependent thermogenic, tachycardic, and hyperthermic ...

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Outbreak of ciprofloxacin-susceptible community-associated meticillin-resistant Staphylococcus aureu

March 19th, 2008
Outbreak of ciprofloxacin-susceptible community-associated meticillin-resistant Staphylococcus aureus in a neonatal unit. Seetulsingh P, Curtis C, Kearns AM. Hemel Hempstead General Hospital, Hemel Hempstead, Hertfordshire, UK.

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First point prevalence survey of nosocomial infections in the intensive care units of a tertiary car

March 19th, 2008
First point prevalence survey of nosocomial infections in the intensive care units of a tertiary care hospital in Albania. Faria S, Sodano L, Dauri M, Sabato AF, Gjata A, Kito I, Llazo E, Bilaj A, Mertiraj O, Schinaia N, The Prevalence Study Group . ...

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Application of the forensic Luminol for blood in infection control.

March 19th, 2008
Application of the forensic Luminol for blood in infection control. Transmission of hepatitis C virus occurs frequently in haemodialysis units. A possible route of transmission is indirectly via the hospital environment although this has never been recorded. We investigated the haemodialysis unit in Deventer Hospital, Deventer, ...

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Winter photosynthetic activity of twenty temperate semi-desert sand grassland species.

March 19th, 2008
Winter photosynthetic activity of twenty temperate semi-desert sand grassland species. The winter photosynthetic activity (quantified by net CO(2) assimilation rates and chlorophyll (Chl) a fluorescence parameters) of 20 plant species (including two lichens and two mosses) of a Hungarian temperate semi-desert sand grassland was determined on ...

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Automated speech analysis applied to laryngeal disease categorization.

March 19th, 2008
Automated speech analysis applied to laryngeal disease categorization. The long-term goal of the work is a decision support system for diagnostics of laryngeal diseases. Colour images of vocal folds, a voice signal, and questionnaire data are the information sources to be used in the analysis. This ...

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Efficacy of pioglitazone on type 2 diabetic patients with hemodialysis.

March 19th, 2008
Efficacy of pioglitazone on type 2 diabetic patients with hemodialysis. AIMS: Unfortunately, growing number of type 2 diabetic hemodialysis (HD) patients with insulin resistance are now being diagnosed in Japan. Worse still, PPARgammaagonists such as pioglitazone are now contraindicated in diabetic HD patients in Japan. In ...

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Endothelin-1 levels and albuminuria in patients with type 2 diabetes mellitus.

March 19th, 2008
Endothelin-1 levels and albuminuria in patients with type 2 diabetes mellitus. AIM: To evaluate the relationship of plasma endothelin-1 (ET-1) levels, a marker of endothelial dysfunction, and urinary albumin excretion in patients with type 2 diabetes mellitus (DM). METHODS: Cross-sectional study was conducted in 279 patients ...

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Mutations in the beta1 adrenergic receptor gene and massive obesity in Japanese.

March 19th, 2008
Mutations in the beta1 adrenergic receptor gene and massive obesity in Japanese. Catecholamines strongly promote lipolysis and thermogenesis, and play a central role in the regulation of body fat content. The beta1 adrenergic receptor (BAR-1) is a major mediator of catecholamine-induced lipolysis and thermogenesis. To explore ...

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[Ischemic bilateral lumbosacral plexopathy and walking disability following surgical treatment of se

March 19th, 2008
[Ischemic bilateral lumbosacral plexopathy and walking disability following surgical treatment of secondary aortoenteric fistulas: A case report.] OBJECTIVE: Aortoenteric fistula is a rare and serious pathology with a high mortality rate (around 50%). The surgery\'s neurological complications are also rare (around 0.25% of reconstructive interventions); two-thirds ...

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Poly(imidazole/DMAEA)phosphazene/DNA self-assembled nanoparticles for gene delivery: Synthesis and i

March 19th, 2008
Poly(imidazole/DMAEA)phosphazene/DNA self-assembled nanoparticles for gene delivery: Synthesis and in vitro transfection. A new cationic derivate of polyphosphazene with imidazole and 2-dimethylaminoethylamino (DMAEA) as side groups, poly(imidazole/DMAEA)phosphazene (PIDP), was synthesized and investigated for gene delivery. The half-lives of PIDP degradation under neutral (pH 7.4) and acidic conditions ...

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