Medical and Biomedical Researches

Neonatal extra-corporeal life support: Indications and limitations.

March 19th, 2008
Neonatal extra-corporeal life support: Indications and limitations. Cardiac extra-corporeal life support is used more frequently in the current era of complex, high-risk neonatal heart surgery. Although outcome for neonates with complex heart disease has improved in the last decade, thanks to advances in surgery and intensive ...

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Effects of reinforcer quality and step size on rats’ performance under progressive ratio schedules.

March 19th, 2008
Effects of reinforcer quality and step size on rats\' performance under progressive ratio schedules. The Mathematical Principles of Reinforcement (MPR) model accurately predicts performance in fixed ratio (FR) schedules of reinforcement. The aim of the present study was to assess the generality of MPR with rats ...

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Prevalence and molecular characterization of bovine Cryptosporidium isolates in India.

March 19th, 2008
Prevalence and molecular characterization of bovine Cryptosporidium isolates in India. A survey based on PCR assay of 18S SSU rRNA gene revealed a 30.2% infection with Cryptosporidium spp., out of 457 faecal samples collected from neonatal bovine calves across three different regions of India. The PCR-RFLP ...

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Epidemiological survey of cestode-larva disease in Greek sheep flocks.

March 19th, 2008
Epidemiological survey of cestode-larva disease in Greek sheep flocks. The epidemiological status of hydatidosis, cysticercosis, and gid in sheep and the production practices of sheep farmers that increase the risk of exposure of sheep to infecting agents of these diseases were investigated in Thessaly, central Greece ...

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Protein expression profile in the amygdala of rats with methamphetamine-induced behavioral sensitiza

March 19th, 2008
Protein expression profile in the amygdala of rats with methamphetamine-induced behavioral sensitization. Repeated exposure to methamphetamine (MAP) results in a progressively enhanced and enduring behavioral response to the drug. This phenomenon is known as behavioral sensitization. MAP-induced sensitization has been suggested to underlie certain aspects of ...

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alphaII-Spectrin breakdown product increases in principal cells in the gerbil main olfactory bulb fo

March 19th, 2008
alphaII-Spectrin breakdown product increases in principal cells in the gerbil main olfactory bulb following transient ischemia. In pathological states, calpains in neurons easily degrade spectrin and yield specific fragments called spectrin breakdown products characterized by their high stabilities both in vitro and in vivo. In the ...

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Memantine increases brain production of kynurenic acid via protein kinase A-dependent mechanism.

March 19th, 2008
Memantine increases brain production of kynurenic acid via protein kinase A-dependent mechanism. We describe a novel aspect of action of memantine ex vivo, in the brain cortical slices and in vitro, in mixed glial cultures. The drug potently increased the production of kynurenic acid, an endogenous ...

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Prefrontal modulation of tactile responses in the ventrobasal thalamus of rats.

March 19th, 2008
Prefrontal modulation of tactile responses in the ventrobasal thalamus of rats. Prefrontal cortex (PFC) has been implicated in modulation of sensory information processing in somatosensory cortex. However, it remains unclear whether or not PFC regulates sensory information in thalamus. In the present study, the effect of ...

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A novel slurry sampling analysis of lead in different water samples by electrothermal atomic absorpt

March 19th, 2008
A novel slurry sampling analysis of lead in different water samples by electrothermal atomic absorption spectrometry after coprecipitated with cobalt/pyrrolidine dithiocarbamate complex. A preconcentration/separation technique based on the coprecipitation of lead with cobalt/pyrrolidine dithiocarbamate complex (Co(PDC)(2)) and subsequently its direct slurry sampling determination by electrothermal atomic ...

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Removal of Cr(VI) and Ni(II) from aqueous solution by fused yeast: Study of cations release and bios

March 19th, 2008
Removal of Cr(VI) and Ni(II) from aqueous solution by fused yeast: Study of cations release and biosorption mechanism. Biosorption of Cr(VI) and Ni(II) by a fused yeast from Candida tropicalis and Candida lipolytica under varying range of pH, initial metal concentration and reaction time was investigated. ...

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Electrostatic separation for multi-size granule of crushed printed circuit board waste using two-rol

March 19th, 2008
Electrostatic separation for multi-size granule of crushed printed circuit board waste using two-roll separator. The electrostatic separation is an effective method for recycle of crushed waste electrical and electronic equipment (WEEE). However, the robustness of the classical roll-type separator is vulnerable because of its sensitivity to ...

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Regulation of the nitric oxide pathway genes by tetrahydrofurandiols: Microarray analysis of MCF-7 h

March 19th, 2008
Regulation of the nitric oxide pathway genes by tetrahydrofurandiols: Microarray analysis of MCF-7 human breast cancer cells. THF-diols (9,12-oxy-10,13-dihydroxyoctadecanoic and 10,13-oxy-9,12-dihydroxyoctadecanoic acids) are endocrine disrupters in rats and mitogens in breast cancer cells. Microarray analyses and real-time PCR analyses on RNA from THF-treated MCF-7 cells revealed ...

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MEK inhibitor enhances the inhibitory effect of imatinib on pancreatic cancer cell growth.

March 19th, 2008
MEK inhibitor enhances the inhibitory effect of imatinib on pancreatic cancer cell growth. Imatinib mesylate (imatinib) inhibits the c-Kit-dependent tyrosine kinase activities and highly effective in the treatment of CML and GIST patients. Although pancreatic cancer is reported to express c-Kit, imatinib does not effectively inhibit ...

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Kaempferol and quercetin stimulate granulocyte-macrophage colony-stimulating factor secretion in hum

March 19th, 2008
Kaempferol and quercetin stimulate granulocyte-macrophage colony-stimulating factor secretion in human prostate cancer cells. Granulocyte-macrophage colony-stimulating factor (GM-CSF) holds immunotherapeutic promise in prostate cancer as it activates the host immune system. Increased production of GM-CSF by cancer cells may facilitate host immunosurveillence by the dendritic cells (DC). ...

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Delineation and functional status monitoring in small saline wetlands of NE Spain.

March 19th, 2008
Delineation and functional status monitoring in small saline wetlands of NE Spain. The small playa-lakes and other saline wetlands of Monegros, scattered over a dry area with winter cereal monoculture, are threatened by the settlement of new irrigation districts and other kinds of human pressure. Enforcing ...

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G-CSF treatment after myocardial infarction: Impact on bone marrow-derived vs cardiac progenitor cel

March 19th, 2008
G-CSF treatment after myocardial infarction: Impact on bone marrow-derived vs cardiac progenitor cells. OBJECTIVE: Besides its classical function in the field of autologous and allogenic stem cell transplantation, granulocyte colony-stimulating factor (G-CSF) was shown to have protective effects after myocardial infarction (MI) by mobilization of bone ...

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Regulation of human B lymphopoiesis by the transforming growth factor-beta superfamily in a newly es

March 19th, 2008
Regulation of human B lymphopoiesis by the transforming growth factor-beta superfamily in a newly established coculture system using human mesenchymal stem cells as a supportive microenvironment. OBJECTIVES: To characterize and evaluate the validity of a novel coculture system for studying human B-lymphocyte developmental biology. MATERIALS AND ...

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R-(-)-gossypol (AT-101) activates programmed cell death in multiple myeloma cells.

March 19th, 2008
R-(-)-gossypol (AT-101) activates programmed cell death in multiple myeloma cells. OBJECTIVE: Bcl-2 family proteins play a critical role in malignancies by regulating the balance between cell survival and apoptosis. R-(-)-gossypol (AT-101) is a small molecule that mimics the BH3 domain of cellular Bcl-2 inhibitors and interferes ...

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Predictive factors for outcomes after reduced intensity conditioning hematopoietic stem cell transpl

March 19th, 2008
Predictive factors for outcomes after reduced intensity conditioning hematopoietic stem cell transplantation for hematological malignancies: a 10-year retrospective analysis from the Société Française de Greffe de Moelle et de Thérapie Cellulaire. This retrospective study analyzed the impact of demographic and transplantation variables on outcomes of 1108 ...

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Deficiency of Src family kinases compromises the repopulating ability of hematopoietic stem cells.

March 19th, 2008
Deficiency of Src family kinases compromises the repopulating ability of hematopoietic stem cells. OBJECTIVE: Src family kinases (SFK) have been implicated in regulating growth factor and integrin-induced proliferation, migration, and gene expression in multiple cell types. However, little is known about the role of these kinases ...

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Rapid platelet turnover in WASP(-) mice correlates with increased ex vivo phagocytosis of opsonized

March 19th, 2008
Rapid platelet turnover in WASP(-) mice correlates with increased ex vivo phagocytosis of opsonized WASP(-) platelets. OBJECTIVE: Our objective was to determine a mechanism for the thrombocytopenia of murine Wiskott-Aldrich syndrome (WAS). MATERIALS AND METHODS: Consumption rates of WAS protein (WASP)(-) and wild-type (WT) platelets were ...

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G-CSF in patients suffering from late revascularized ST elevation myocardial infarction: Analysis on

March 19th, 2008
G-CSF in patients suffering from late revascularized ST elevation myocardial infarction: Analysis on the timing of G-CSF administration. OBJECTIVE: Granulocyte colony-stimulating factor (G-CSF) improves myocardial function after infarction in vivo. Placebo-controlled clinical studies failed to show beneficial effects on myocardial function. Recent data demonstrate that the ...

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Structural stability and reversible unfolding of recombinant porcine S100A12.

March 19th, 2008
Structural stability and reversible unfolding of recombinant porcine S100A12. Porcine S100A12 is a member of the S100 proteins, family of small acidic calcium-binding proteins characterized by the presence of two EF-hand motifs. These proteins are involved in many cellular events such as the regulation of protein ...

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Respiration, metabolic balance, and attention in affective picture processing.

March 19th, 2008
Respiration, metabolic balance, and attention in affective picture processing. The respiratory behavior during affective states is not completely understood. We studied breathing pattern responses to picture series in 37 participants. We also measured end-tidal pCO(2) (EtCO(2)) to determine if ventilation is in balance with metabolic demands ...

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Neurotransmitter, peptide and cytokine processes in relation to depressive disorder: Comorbidity bet

March 19th, 2008
Neurotransmitter, peptide and cytokine processes in relation to depressive disorder: Comorbidity between depression and neurodegenerative disorders. Given the array of biological changes induced by stressors, it is not surprising that these experiences may provoke a variety of illnesses. Among others things, stressors promote functional changes of ...

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