Medical and Biomedical Researches

Trigeminal activation using chemical, electrical, and mechanical stimuli.

June 29th, 2008
Trigeminal activation using chemical, electrical, and mechanical stimuli. Tactile, proprioceptive, and nociceptive information, including also chemosensory functions are expressed in the trigeminal nerve sensory response. To study differences in the processing of different stimulus qualities, we performed a study based on functional magnetic resonance imaging. The ...

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Ralfinamide administered orally before hindpaw neurectomy or postoperatively provided long-lasting s

June 29th, 2008
Ralfinamide administered orally before hindpaw neurectomy or postoperatively provided long-lasting suppression of spontaneous neuropathic pain-related behavior in the rat. Ralfinamide is analgesic when applied as a single dose in rodent models of stimulus-evoked chronic pain. However, it is unknown whether its chronic application after nerve injury ...

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Oral opioid use alters DNIC but not cold pain perception in patients with chronic pain - New perspec

June 29th, 2008
Oral opioid use alters DNIC but not cold pain perception in patients with chronic pain - New perspective of opioid-induced hyperalgesia. Opioids can elicit unexpected changes in pain sensitivity, known as opioid-induced hyperalgesia (OIH). The aim of this study was to explore whether OIH exists in ...

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Delayed preconditioning effect of isoflurane on spinal cord ischemia in rats.

June 29th, 2008
Delayed preconditioning effect of isoflurane on spinal cord ischemia in rats. Paraplegia is one of the most common complications following aortic aneurysmal surgery. This study was designed to determine if isoflurane-induced delayed preconditioning is mediated by nuclear factor kappaB (NF-kappaB) in the rat spinal cord. The ...

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Transient receptor potential ankyrin-1 participates in visceral hyperalgesia following experimental

June 29th, 2008
Transient receptor potential ankyrin-1 participates in visceral hyperalgesia following experimental colitis. Transient receptor potential ankyrin-1 (TRPA1) is an important receptor that contributes to inflammatory pain. However, previous studies were mainly concerned with its function in somatic hyperalgesia while few referred to visceral, especially colonic inflammatory hyperalgesia. ...

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Statin inhibits kainic acid-induced seizure and associated inflammation and hippocampal cell death.

June 29th, 2008
Statin inhibits kainic acid-induced seizure and associated inflammation and hippocampal cell death. Statins are inhibitors of HMG-CoA reductase that have been recently recognized as anti-inflammatory and neuroprotective drugs. Herein, we investigated anti-excitotoxic and anti-seizure effects of statins by using kainic acid (KA)-rat seizure model, an animal ...

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Effects of nicotine, methamphetamine and cocaine on extracellular levels of acetylcholine in the int

June 29th, 2008
Effects of nicotine, methamphetamine and cocaine on extracellular levels of acetylcholine in the interpeduncular nucleus of rats. There is increasing evidence that the cholinergic habenulo-interpeduncular pathway and the dopaminergic mesolimbic pathway may jointly mediate the reinforcing properties of addictive drugs. However, the effects of addictive drug ...

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Exposure to metal ions regulates mRNA levels of APP and BACE1 in PC12 cells: Blockage by curcumin.

June 29th, 2008
Exposure to metal ions regulates mRNA levels of APP and BACE1 in PC12 cells: Blockage by curcumin. Amyloid beta peptide (Abeta), generated by proteolytic cleavage of the amyloid precursor protein (APP), play a pivotal role in the pathogenesis of Alzheimer\'s disease (AD). The key step in ...

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Alterations in neuronal calcium levels are associated with cognitive deficits after traumatic brain

June 29th, 2008
Alterations in neuronal calcium levels are associated with cognitive deficits after traumatic brain injury. Traumatic brain injury (TBI) survivors often suffer from a post-traumatic syndrome with deficits in learning and memory. Calcium (Ca(2+)) has been implicated in the pathophysiology of TBI-induced neuronal death. However, the role ...

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Novel approach to zinc removal from circum-neutral mine waters using pelletised recovered hydrous fe

June 29th, 2008
Novel approach to zinc removal from circum-neutral mine waters using pelletised recovered hydrous ferric oxide. Data are presented which evaluate the performance of a pilot-scale treatment system using pelletised hydrous ferric oxide (HFO; a waste stream from coal mine water treatment) as a high surface area ...

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Effect of soda ash industry effluent on agarophytes, alginophytes and carrageenophyte of west coast

June 29th, 2008
Effect of soda ash industry effluent on agarophytes, alginophytes and carrageenophyte of west coast of India. This paper presents the results of a study on the impact of the effluent released by the soda ash industry on important red and brown macro algal species Gelidiella acerosa, ...

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Separation and preconcentration of cadmium ions using octadecyl silica membrane disks modified by me

June 29th, 2008
Separation and preconcentration of cadmium ions using octadecyl silica membrane disks modified by methyltrioctylammonium chloride. A simple and selective method for the determination of cadmium in water samples by FAAS after solid phase extraction has been developed. The method is based on the sorption of cadmium ...

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Effect of structural properties of acid dyes on their adsorption behaviour from aqueous solutions by

June 29th, 2008
Effect of structural properties of acid dyes on their adsorption behaviour from aqueous solutions by amine modified silica. Monoamine modified silica particles (MAMS) were prepared and characterized by infrared (FT-IR) and thermogravimetric analysis (TGA). The modified silica particles were used for removal of acid orange 10 ...

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Impact of nocturnal planetary boundary layer on urban air pollutants: Measurements from a 250-m towe

June 29th, 2008
Impact of nocturnal planetary boundary layer on urban air pollutants: Measurements from a 250-m tower over Tianjin, China. It is well known that nocturnal planetary boundary layer (NPBL) has important effects on urban air pollutants. However, the direct measurements of the interactions between the NPBL height ...

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Arsenic adsorption from aqueous solution on synthetic zeolites.

June 29th, 2008
Arsenic adsorption from aqueous solution on synthetic zeolites. The adsorption of arsenic from aqueous solution on synthetic zeolites H-MFI-24 (H24) and H-MFI-90 (H90) with MFI topology has been investigated at room temperature (r.t) applying batch equilibrium techniques. The influences of different sorption parameters such as contact ...

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Long-term leaching from MSWI air-pollution-control residues: Leaching characterization and modeling.

June 29th, 2008
Long-term leaching from MSWI air-pollution-control residues: Leaching characterization and modeling. Long-term leaching of Ca, Fe, Mg, K, Na, S, Al, As, Ba, Cd, Co, Cr, Cu, Hg, Mn, Ni, Pb, Zn, Mo, Sb, Si, Sn, Sr, Ti, V, P, Cl, and dissolved organic carbon from two ...

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Simple and effective synthesis of methoxy-dimethylbenzene from electrochemical oxidation of p-xylene

June 29th, 2008
Simple and effective synthesis of methoxy-dimethylbenzene from electrochemical oxidation of p-xylene in methanol solvent catalyzed by SO(4)(2-)/ZrO(2)-M(x)O(y). A series of composite solid superacid catalysts SO(4)(2-)/ZrO(2)-M(x)O(y) (M=Ti, Ni, Si) were prepared and investigated by means of Fourier transform infrared (FT-IR) and X-ray photoelectron spectroscopy (XPS). All catalysts ...

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Treatment of water-based printing ink wastewater by Fenton process combined with coagulation.

June 29th, 2008
Treatment of water-based printing ink wastewater by Fenton process combined with coagulation. Attempts were made in this study to examine the efficiency of Fenton process combined with coagulation for treatment of water-based printing ink wastewater. Parameters affecting the Fenton process, such as pH, dosages of Fenton ...

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Chlorobenzene, chloroform, and carbon tetrachloride adsorption on undoped and metal-doped sol-gel su

June 29th, 2008
Chlorobenzene, chloroform, and carbon tetrachloride adsorption on undoped and metal-doped sol-gel substrates (SiO(2), Ag/SiO(2), Cu/SiO(2) and Fe/SiO(2)). Adsorption isotherms of chlorobenzene, chloroform and carbon tetrachloride vapors on undoped SiO(2), and metal-doped Ag/SiO(2), Cu/SiO(2) and Fe/SiO(2) substrates were measured in the temperature range of 398-593K. These substrates ...

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Down regulation of c-Myc and induction of an angiogenesis inhibitor, thrombospondin-1, by 5-FU in hu

June 29th, 2008
Down regulation of c-Myc and induction of an angiogenesis inhibitor, thrombospondin-1, by 5-FU in human colon cancer KM12C cells. 5-FU is commonly used for treatment of various solid tumors including colon carcinoma. We have previously demonstrated that Egr-1 induced by 5-FU enhanced TSP-1 expression in human ...

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Treatment outcome correlates with knowledge of disease in hemifacial spasm.

June 29th, 2008
Treatment outcome correlates with knowledge of disease in hemifacial spasm. OBJECTIVES: Hemifacial spasm (HFS), a potentially disabling facial condition affects quality of life (QOL) and botulinum toxin is an effective treatment. No studies have examined whether a better level of knowledge of the disease would lead ...

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Modulation of transcription parameters in glucocorticoid receptor-mediated repression.

June 29th, 2008
Modulation of transcription parameters in glucocorticoid receptor-mediated repression. Glucocorticoid receptors (GRs) affect both gene induction and gene repression. The disparities of receptor binding to DNA and increased vs. decreased gene expression have suggested significant mechanistic differences between GR-mediated induction and repression. Numerous transcription factors are known ...

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Edysone receptor isoforms play distinct roles in controlling molting and metamorphosis in the red fl

June 29th, 2008
Edysone receptor isoforms play distinct roles in controlling molting and metamorphosis in the red flour beetle, Tribolium castaneum. Ecdysteroids regulate insect growth and development through a heterodimeric complex of nuclear receptors consisting of ecdysone receptor (EcR) and ultraspiracle (USP). In the red flour beetle, Tribolium castaneum, ...

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Biased Brownian motion mechanism for processivity and directionality of single-headed myosin-VI.

June 29th, 2008
Biased Brownian motion mechanism for processivity and directionality of single-headed myosin-VI. Conventional form to function as a vesicle transporter is not a \'single molecule\' but a coordinated \'two molecules\'. The coordinated two molecules make it complicated to reveal its mechanism. To overcome the difficulty, we adopted ...

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Fluctuation as a tool of biological molecular machines.

June 29th, 2008
Fluctuation as a tool of biological molecular machines. The mechanism for biological molecular machines is different from that of man-made ones. Recently single molecule measurements and other experiments have revealed unique operations where biological molecular machines exploit thermal fluctuation in response to small inputs of energy ...

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