Medical and Biomedical Researches

Personality traits in children of parents with unipolar and bipolar mood disorders.

July 3rd, 2008
Personality traits in children of parents with unipolar and bipolar mood disorders. BACKGROUND: Using family study data, the following questions regarding the mechanisms of association between personality traits and mood disorders were addressed: 1) Is there an association between unipolar and bipolar mood disorders and personality ...

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Confocal microscopy in large insect brains: Zinc-formaldehyde fixation improves synapsin immunostain

July 3rd, 2008
Confocal microscopy in large insect brains: Zinc-formaldehyde fixation improves synapsin immunostaining and preservation of morphology in whole-mounts. Confocal microscopy enables the analysis of immunofluorescence in whole-mount brains and is therefore widely used in the functional and comparative neuroanatomy of invertebrates. Three difficulties, however, are commonly encountered. ...

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Muscle-joint unit transfer function derived from torque and surface mechanomyogram in humans using d

July 3rd, 2008
Muscle-joint unit transfer function derived from torque and surface mechanomyogram in humans using different stimulation protocols. Torque and laser detected surface mechanomyogram (MMG) analysis after electrical stimulation of human tibialis anterior (TA) of 14 male subjects was aimed to: (a) obtain the dynamic responses of TA ...

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Discrimination of cell types in mixed cortical culture using calcium imaging: A comparison to immuno

July 3rd, 2008
Discrimination of cell types in mixed cortical culture using calcium imaging: A comparison to immunocytochemical labeling. Neuronal-glial interactions in the central nervous system are important for both normal function and response to pathological states. Differences in calcium processing between these cell types may be exploited to ...

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Interaction of human PD-L1 and B7-1.

July 3rd, 2008
Interaction of human PD-L1 and B7-1. Numerous studies have pointed to the role of programmed death-1 ligand 1 (PD-L1) in regulating tolerance, chronic infection, and tumor immunity. Recently, we have identified murine B7-1 as a new binding partner for murine PD-L1. Human and mouse B7-1 share ...

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I. VH gene transcription creates stabilized secondary structures for coordinated mutagenesis during

July 3rd, 2008
I. VH gene transcription creates stabilized secondary structures for coordinated mutagenesis during somatic hypermutation. During the adaptive immune response, antigen challenge triggers a million-fold increase in mutation rates in the variable-region antibody genes. The frequency of mutation is causally and directly linked to transcription, which provides ...

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A new role for complement C3: Regulation of antigen processing through an inhibitory activity.

July 3rd, 2008
A new role for complement C3: Regulation of antigen processing through an inhibitory activity. Increasing evidence underlines the involvement of complement component C3 in the establishment of acquired immunity which appears to play a complex role and to act at different levels. As antigen proteolysis by ...

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Is neurogenic hypertension related to vascular inflammation of the brainstem?

July 3rd, 2008
Is neurogenic hypertension related to vascular inflammation of the brainstem? Essential hypertension is idiopathic although it is accepted as a complex polygenic trait with underlying genetic components, which remain unknown. Our supposition is that hypertension involves activation of the sympathetic nervous system. One pivotal region controlling ...

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Chronic social stress, hedonism and vulnerability to obesity: Lessons from Rodents.

July 3rd, 2008
Chronic social stress, hedonism and vulnerability to obesity: Lessons from Rodents. Obesity is a current health pandemia. Determinants of this pathology are rather complex and include genetic, developmental and environmental factors only partially disclosed. Stress related neuroendocrine dysregulation and overconsumption of high palatable high caloric food ...

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Regression of chronic lymphocytic leukemia with aromatase inhibitor-letrozole?

July 3rd, 2008
Regression of chronic lymphocytic leukemia with aromatase inhibitor-letrozole? Here a case with breast cancer (BC) and chronic lymphocytic leukemia-B (CLL-B) cell type was presented. Interestingly, CLL regressed during aromatase inhibitor (AI) therapy. The possible definition of this regression was discussed in this paper. Paydas S. ...

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Nanofibrous polyhydroxyalkanoate matrices as cell growth supporting materials.

July 3rd, 2008
Nanofibrous polyhydroxyalkanoate matrices as cell growth supporting materials. Polyhydroxyalkanoates (PHAs) have been demonstrated to be a family of biopolymers with good biodegradability and biocompatibility. To mimic the real microenvironment of extracellular matrix (ECM) for cell growth, novel nanofiber matrices based on PHA polymers were prepared via ...

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Acid-degradable cationic methacrylamide polymerized in the presence of plasmid DNA as tunable non-vi

July 3rd, 2008
Acid-degradable cationic methacrylamide polymerized in the presence of plasmid DNA as tunable non-viral gene carrier. New acid-degradable cationic nanoparticles were synthesized using a monomer-to-polymer approach, which enabled highly flexible nanoparticle fabrication to obtain controlled properties such as size and conjugation with additional functionalities. The nanoparticles were ...

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In vivo expression of osteogenic markers and bone mineral density at the surface of fluoride-modifie

July 3rd, 2008
In vivo expression of osteogenic markers and bone mineral density at the surface of fluoride-modified titanium implants. The aim of the present study was to investigate the biological mechanisms of the functional attachment of fluoride-modified titanium implants to cortical bone by studying the association of the ...

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An in vitro and in vivo evaluation of bioactive titanium implants following sodium removal treatment

July 3rd, 2008
An in vitro and in vivo evaluation of bioactive titanium implants following sodium removal treatment. OBJECTIVE: The aim of this study was to evaluate the effect of dilute HCl as a sodium removal treatment of grit blasted/NaOH/heat treated cp titanium implants on the in vitro bioactivity ...

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Metal mesh vitrification (MMV) method for cryopreservation of porcine embryos.

July 3rd, 2008
Metal mesh vitrification (MMV) method for cryopreservation of porcine embryos. The objective was to develop a simpler, more reliable vitrification method for porcine embryos. Prepubertal donor gilts were induced to ovulate with eCG and hCG, and then inseminated artificially. Morulae and expanding blastocysts approximately 200mum in ...

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The antioxidant epigallocatechin gallate (EGCG) moderates the deleterious effects of maternal hypert

July 3rd, 2008
The antioxidant epigallocatechin gallate (EGCG) moderates the deleterious effects of maternal hyperthermia on follicle-enclosed oocytes in mice. Hyperthermia-induced oxidative stress is one of the mechanisms suggested to underlie loss of developmental competence in mouse embryos. In this study, we examined whether pretreatment with the antioxidant epigallocatechin ...

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Spontaneous contractility of bovine myometrium in vitro depending on topography and cycle phase.

July 3rd, 2008
Spontaneous contractility of bovine myometrium in vitro depending on topography and cycle phase. The bovine myometrium exerts different contractility patterns in dependency of the reproductive state. However, little is known about the contractile behaviour of the uterus in the cow regarding topography. Differences in the in ...

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Global Youth Tobacco Survey (GYTS) in Indonesia.

July 3rd, 2008
Global Youth Tobacco Survey (GYTS) in Indonesia. OBJECTIVES: Indonesia has the fifth highest rate of annual cigarette consumption per person of all countries worldwide. The Global Youth Tobacco Survey (GYTS) was developed to provide data on youth tobacco use to countries for their development of youth-based ...

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The pediatric residency training on tobacco project: Four-year parent outcome findings.

July 3rd, 2008
The pediatric residency training on tobacco project: Four-year parent outcome findings. OBJECTIVE: To assess parent behavioral change and perception of resident intervention on tobacco. METHODS: In a long-term study of the efficacy of training pediatric residents to address tobacco conducted at the New Jersey Medical School, ...

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Repetitive organic dust exposure in vitro impairs macrophage differentiation and function.

July 3rd, 2008
Repetitive organic dust exposure in vitro impairs macrophage differentiation and function. BACKGROUND: Organic dust exposure in the agricultural industry results in significant airway disease and lung function decrease. Mononuclear phagocytes are key cells that mediate the inflammatory and innate immune response after dust exposure. OBJECTIVE: We ...

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Mini-Incision Microsurgical Vasectomy Reversal Using No-Scalpel Vasectomy Principles and Instruments

July 3rd, 2008
Mini-Incision Microsurgical Vasectomy Reversal Using No-Scalpel Vasectomy Principles and Instruments. OBJECTIVES: Men who have undergone a vasectomy have 2 options available to allow them to have biologically related children: vasectomy reversal or sperm retrieval with in vitro fertilization. Of the men who have undergone vasectomy, 2%-11% ...

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Single-Institutional Study on Role of Ureteroscopy and Retrograde Intrarenal Surgery in Treatment of

July 3rd, 2008
Single-Institutional Study on Role of Ureteroscopy and Retrograde Intrarenal Surgery in Treatment of Pediatric Renal Calculi. OBJECTIVES: Ureteroscopy (URS) is accepted as a primary modality to treat ureteral calculi in children and extracorporeal shock wave lithotripsy and percutaneous nephrolithotomy continue to be the primary option for ...

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Genital and Reproductive Function in Males After Functional Reconstruction of the Exstrophy-Epispadi

July 3rd, 2008
Genital and Reproductive Function in Males After Functional Reconstruction of the Exstrophy-Epispadias Complex-Long-Term Results. OBJECTIVES: Genital and reproductive function have a strong effect on the quality of life of adolescent and adult male patients with the exstrophy-epispadias complex (EEC). According to the limited available data, early ...

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Posterior Urethral Valves: Search for a Diagnostic Reference Standard.

July 3rd, 2008
Posterior Urethral Valves: Search for a Diagnostic Reference Standard. OBJECTIVES: To test the agreement among pediatric urologists regarding endoscopic findings concerning posterior urethral valves. METHODS: A total of 25 experienced pediatric urologic surgeons observed 11 video fragments of cystourethroscopy in boys. For most of these boys, ...

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Results of the performance verification of the CoaguChek XS system.

July 3rd, 2008
Results of the performance verification of the CoaguChek XS system. BACKGROUND: This is the first paper reporting a performance verification study of a point-of-care (POC) monitor for prothrombin time (PT) testing according to the requirements given in chapter 8 of the International Organization for Standardization (ISO) ...

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