Medical and Biomedical Researches

Arterial oxygen partial pressure and cardiovascular surgery in elderly patients.

June 29th, 2008
Arterial oxygen partial pressure and cardiovascular surgery in elderly patients. Arterial blood gas assessment is still routinely performed in candidates for a cardiovascular surgery. Whether sampling arterial blood is useful in an elderly patient with a near normal lung function and who meets all other criteria ...

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Repair of an acute type A aortic dissection combined with an emergency cesarean section in a pregnan

June 29th, 2008
Repair of an acute type A aortic dissection combined with an emergency cesarean section in a pregnant woman. This case report describes a 35-week pregnant woman presenting with an acute type A aortic dissection. She underwent a successful emergency surgical repair and a concomitant cesarean section ...

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Folate intake, markers of folate status and oral clefts: is the evidence converging?

June 29th, 2008
Folate intake, markers of folate status and oral clefts: is the evidence converging? BACKGROUND: The ability of folic acid in the periconceptional period to prevent the occurrence of neural tube defects has stimulated tremendous interest in its effects on other health outcomes. Its possible effect on ...

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Risk factors across the life course and dementia in a Brazilian population: results from the Sao Pau

June 29th, 2008
Risk factors across the life course and dementia in a Brazilian population: results from the Sao Paulo Ageing & Health Study (SPAH). BACKGROUND: Several mechanisms have been suggested to explain the association between adversities across life and dementia. This study aimed to investigate the association between ...

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Evaluation of the sensitivity to chemotherapeutics or thiazolidinediones of primary anaplastic thyro

June 29th, 2008
Evaluation of the sensitivity to chemotherapeutics or thiazolidinediones of primary anaplastic thyroid cancer cells obtained by fine-needle aspiration. Objective: Anaplastic thyroid cancer (ATC) is often unoperable and chemotherapy and radiotherapy are the main treatments. Until now primary ATC cell cultures (ANA) have been developed from surgical ...

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Hypochondroplasia and acanthosis nigricans: a new syndrome due to the p.Lys650Thr mutation in the FG

June 29th, 2008
Hypochondroplasia and acanthosis nigricans: a new syndrome due to the p.Lys650Thr mutation in the FGFR3 gene? Hypochondroplasia (HCH) is a skeletal dysplasia inherited in an autosomal dominant manner due, in most cases, to mutations in the fibroblast growth factor receptor 3 (FGFR3). Acanthosis nigricans (AN) is ...

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Lack of Association of Liver Fat with Model Parameters of Beta-Cell Function in Men with Impaired Gl

June 29th, 2008
Lack of Association of Liver Fat with Model Parameters of Beta-Cell Function in Men with Impaired Glucose Tolerance and Type 2 Diabetes. Objective: Hepatic steatosis and obesity are components of the metabolic syndrome and risk factors for developing type 2 diabetes (T2DM). We studied how liver ...

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High Degree of Transferability of 86 Newly Developed Zebra Finch EST-Linked Microsatellite Markers i

June 29th, 2008
High Degree of Transferability of 86 Newly Developed Zebra Finch EST-Linked Microsatellite Markers in 8 Bird Species. High-resolution analysis for population genetic and functional studies requires the use of large numbers of polymorphic markers. The recent increase of available genetic tools is facilitated by the use ...

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Genetic Structure and Mating System of Euterpe edulis Mart. Populations: A Comparative Analysis Usin

June 29th, 2008
Genetic Structure and Mating System of Euterpe edulis Mart. Populations: A Comparative Analysis Using Microsatellite and Allozyme Markers. A comparative study between microsatellite and allozyme markers was conducted on the genetic structure and mating system in natural populations of Euterpe edulis Mart. Three cohorts, including seedlings, ...

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Reactive oxygen species from the uncoupling of human cytochrome P450 1B1 may contribute to the carci

June 29th, 2008
Reactive oxygen species from the uncoupling of human cytochrome P450 1B1 may contribute to the carcinogenicity of dioxin-like polychlorinated biphenyls. Polychlorinated biphenyls (PCBs) are classified by the International Agency for Research on Cancer as probable human carcinogens. A subset of PCBs are described as \'dioxin like\' ...

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Endurance capacity in maturing mdx mice is markedly enhanced by combined voluntary wheel running and

June 29th, 2008
Endurance capacity in maturing mdx mice is markedly enhanced by combined voluntary wheel running and green tea extract. Duchenne muscular dystrophy is characterized by the absence of dystrophin from muscle cells. Dystrophic muscle cells are susceptible to oxidative stress. We tested the hypothesis that 3 weeks ...

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EXERCISE TRAINING INITIATED AFTER THE ONSET OF DIABETES PRESERVES MYOCARDIAL FUNCTION: EFFECTS ON EX

June 29th, 2008
EXERCISE TRAINING INITIATED AFTER THE ONSET OF DIABETES PRESERVES MYOCARDIAL FUNCTION: EFFECTS ON EXPRESSION OF {beta}-ADRENOCEPTORS. The present study was undertaken to assess cardiac function and characterize beta-adrenoceptor subtypes in hearts of diabetic rats that underwent exercise training (ExT) after the onset of diabetes. Type 1 ...

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AIRWAY CONSTRICTION MEASURED FROM TANTALUM BRONCHOGRAMS IN CONSCIOUS MICE IN RESPONSE TO METHACHOLIN

June 29th, 2008
AIRWAY CONSTRICTION MEASURED FROM TANTALUM BRONCHOGRAMS IN CONSCIOUS MICE IN RESPONSE TO METHACHOLINE. A single projection x-ray technique showed an increase in FRC in conscious mice in response to aerosolized methacholine (Mch) with little change in airway resistance (Raw) measured using noninvasive barometric plethysmography (J. Appl. ...

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Increased central facilitation of antagonist reciprocal inhibition at the onset of dorsiflexion foll

June 29th, 2008
Increased central facilitation of antagonist reciprocal inhibition at the onset of dorsiflexion following explosive strength training. At the onset of dorsiflexion disynaptic reciprocal inhibition (DRI) of soleus motoneurons is increased in order to prevent activation of the antagonistic plantar flexors. This is caused by descending facilitation ...

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Formation and maintenance of ventilatory long-term facilitation require NMDA but not non-NMDA recept

June 29th, 2008
Formation and maintenance of ventilatory long-term facilitation require NMDA but not non-NMDA receptors in awake rats. NMDA receptor antagonism in the phrenic motonucleus area eliminates phrenic long-term facilitation (pLTF, a persistent augmentation of phrenic nerve activitiy after episodic hypoxia) in anesthetized rats. However, whether NMDA antagonism ...

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Seven days of oral taurine supplementation does not increase muscle taurine content or alter substra

June 29th, 2008
Seven days of oral taurine supplementation does not increase muscle taurine content or alter substrate metabolism during prolonged exercise in humans. This study examined 1) the plasma taurine response to acute oral taurine supplementation (T), and 2) the effects of 7 days (d) of T on ...

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Exercise training improves peripheral chemoreflex function in heart failure rabbits.

June 29th, 2008
Exercise training improves peripheral chemoreflex function in heart failure rabbits. An enhancement of peripheral chemoreflex sensitivity contributes to sympathetic hyperactivity in chronic heart failure (CHF) rabbits. The enhanced chemoreflex function in CHF involves augmented carotid body (CB) chemoreceptor activity via upregulation of the angiotensin (Ang) II-AT1 ...

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Finite Element 3D Reconstruction of the pulmonary acinus imaged by Synchrotron X-ray tomography.

June 29th, 2008
Finite Element 3D Reconstruction of the pulmonary acinus imaged by Synchrotron X-ray tomography. The alveolated structure of the pulmonary acinus plays a vital role in gas exchange function. Three-dimensional (3D) analysis of the parenchymal region is fundamental to understanding this structure-function relationship, but only a limited ...

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Habitual Exercise and Arterial Aging.

June 29th, 2008
Habitual Exercise and Arterial Aging. Aging affects the function and structure of arteries and increases the risk of cardiovascular diseases (CVD). In healthy sedentary adults, aging is associated with increased stiffness (reduced compliance) of large elastic arteries, impaired vascular endothelial function including reductions in endothelium-dependent dilation ...

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Point Counterpoint.

June 29th, 2008
Point Counterpoint. n/a Key words: cerebral blood flow, sympathetic activity. Van Lieshout JJ, Secher NH, Strandgaard S, Sigurdsson ST. Academic Medical Center.

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Testing for recombinant human erythropoietin in urine: problems associated with current anti doping

June 29th, 2008
Testing for recombinant human erythropoietin in urine: problems associated with current anti doping testing. Background: The main action of recombinant human erythropoietin (rHuEpo) is to increase the oxygen carrying capacity of the blood. To prevent a possible misuse of rHuEpo, this is tested in urine samples ...

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THE US RADON PROBLEM, POLICY, PROGRAM AND INDUSTRY: ACHIEVEMENTS, CHALLENGES AND STRATEGIES.

June 29th, 2008
THE US RADON PROBLEM, POLICY, PROGRAM AND INDUSTRY: ACHIEVEMENTS, CHALLENGES AND STRATEGIES. US radon research, policy and programs have stalled since their start in the late 1980s and early 1990s. In 2005, more homes had radon above the US Environmental Protection Agency (EPA) Reference Level than ...

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COMPARATIVE STUDY OF IMAGE QUALITY FOR MSCT AND CBCT SCANNERS FOR DENTOMAXILLOFACIAL RADIOLOGY APPLI

June 29th, 2008
COMPARATIVE STUDY OF IMAGE QUALITY FOR MSCT AND CBCT SCANNERS FOR DENTOMAXILLOFACIAL RADIOLOGY APPLICATIONS. The image quality of four cone-beam computed tomography (CBCT) scanners dedicated for dentomaxillofacial imaging and one multi-slice computed tomgoraphy (MSCT) scanner was compared. For the MSCT scanner, a clinical and a low-dose ...

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PRELIMINARY OSL STUDIES ON BEIGE SEPIOLITES.

June 29th, 2008
PRELIMINARY OSL STUDIES ON BEIGE SEPIOLITES. Radiation-induced luminescence signals in beige sepiolite samples were investigated using optically stimulated luminescence. A thermally stable, light-sensitive radiation-induced signal was detected, and radiation dose response and thermal properties of this signal were studied. The thermal stability and dose sensitivity of ...

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Inhalation Dosimetry Modeling with Inhaled Decamethylcyclopentasiloxane in Rats and Humans.

June 29th, 2008
Inhalation Dosimetry Modeling with Inhaled Decamethylcyclopentasiloxane in Rats and Humans. Decamethylcyclopentasiloxane (D(5)), a volatile cyclic methyl siloxane (VCMS), is used in industrial and consumer products. Inhalation pharmacokinetics of another VCMS, octamethylcyclotetrasiloxane (D(4)), have been extensively investigated and successfully modeled with a multi-species physiologically based pharmacokinetic (PBPK) ...

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