Medical and Biomedical Researches

P846, a new gadolinium based low diffusion magnetic resonance contrast agent, in characterizing occl

May 1st, 2008
P846, a new gadolinium based low diffusion magnetic resonance contrast agent, in characterizing occlusive infarcts, reperfused ischemic myocardium and reperfused infarcts in rats. OBJECT: This study has two objectives: (1) to compare the kinetics of low diffusion P846 with Gd-DOTA using inversion recovery echo planar (IR-EPI) ...

Posted in Uncategorized | No Comments »

Regulatory mechanisms controlling antibiotic production in Streptomyces clavuligerus.

May 1st, 2008
Regulatory mechanisms controlling antibiotic production in Streptomyces clavuligerus. Streptomyces clavuligerus produces a large array of natural compounds with antibiotic, antitumor, beta-lactamase inhibition or inmunomodulating activities. The production of cephamycin C, clavulanic acid and other compounds with a clavam structure has been studied for many years. A ...

Posted in Uncategorized | No Comments »

An economic evaluation of a perindopril-based blood pressure lowering regimen for patients who have

May 1st, 2008
An economic evaluation of a perindopril-based blood pressure lowering regimen for patients who have suffered a cerebrovascular event. OBJECTIVES: Cerebrovascular disease (or stroke) is one of the main causes of long-term disability and the second leading cause of death worldwide. The economic impact of stroke is ...

Posted in Uncategorized | No Comments »

Vagus nerve stimulation (VNS) is effective in treating catastrophic 1 epilepsy in very young childre

May 1st, 2008
Vagus nerve stimulation (VNS) is effective in treating catastrophic 1 epilepsy in very young children. The objective of this study is to evaluate the safety and efficacy of vagus nerve stimulation (VNS) in very young children suffering from catastrophic epilepsy and status epilepticus. We reviewed files ...

Posted in Uncategorized | No Comments »

Preoperative imaging procedures for lower wisdom teeth removal.

May 1st, 2008
Preoperative imaging procedures for lower wisdom teeth removal. The aims of this paper were to critically review the role of radiographic imaging before lower third molar removal and to suggest a strategy for preoperative imaging based on available scientific evidence and clinical experience. Original articles and ...

Posted in Uncategorized | No Comments »

The effect of periodontal treatment on metabolic control of type 1 diabetes mellitus.

May 1st, 2008
The effect of periodontal treatment on metabolic control of type 1 diabetes mellitus. The objective of this investigation was to study the effect of nonsurgical periodontal treatment, with or without systemic administration of doxycycline, on the metabolic control of patients with type 1 diabetes. Sixty type ...

Posted in Uncategorized | No Comments »

Long-range charge transport through double-stranded DNA mediated by manganese or iron porphyrins.

May 1st, 2008
Long-range charge transport through double-stranded DNA mediated by manganese or iron porphyrins. Guanine oxidation by electron transfer results in the formation of a guanine radical cation, which is at the origin of long-range charge transport through double-stranded DNA. It is possible to observe guanine lesions at ...

Posted in Uncategorized | No Comments »

“Iron priming” guides folding of denatured aporubredoxins.

May 1st, 2008
\"Iron priming\" guides folding of denatured aporubredoxins. The relationship between iron uptake by aporubredoxins (apoRds) and formation of native holorubredoxins (holoRd), including their Fe(SCys)(4) sites, was studied. In the absence of denaturants, apoRds exhibited spectroscopic features consistent with structures very similar to those of the folded ...

Posted in Uncategorized | No Comments »

The international spine registry SPINE TANGO: status quo and first results.

May 1st, 2008
The international spine registry SPINE TANGO: status quo and first results. With an official life time of over 5 years, Spine Tango can meanwhile be considered the first international spine registry. In this paper we present an overview of frequency statistics of Spine Tango for demonstrating ...

Posted in Uncategorized | No Comments »

Revision strategies for complications and failure of vertebroplasties.

May 1st, 2008
Revision strategies for complications and failure of vertebroplasties. Percutaneous vertebroplasty is widely discussed in the management of osteoporotic spinal compression fracture, but few reports are available concerning salvage procedures after failure of this technique. We studied 22 percutaneous vertebroplasty patients who required revision surgery upon presentation ...

Posted in Uncategorized | No Comments »

Cerebral glucose metabolic abnormality in patients with congenital scoliosis.

May 1st, 2008
Cerebral glucose metabolic abnormality in patients with congenital scoliosis. A possible association between congenital scoliosis and low mental status has been recognized, but there are no reports describing the mental status or cerebral metabolism in patients with congenital scoliosis in detail. We investigated the mental status ...

Posted in Uncategorized | No Comments »

Study of the effect of donor source on graft and patient survival in pediatric renal transplant reci

May 1st, 2008
Study of the effect of donor source on graft and patient survival in pediatric renal transplant recipients. Evaluation of the impact of live unrelated kidney donor (LURD) source on the outcome of renal transplantation is not adequately studied. We aimed to compare the long-term outcome of ...

Posted in Uncategorized | No Comments »

Genetic causes of hypercalciuric nephrolithiasis.

May 1st, 2008
Genetic causes of hypercalciuric nephrolithiasis. Renal stone disease (nephrolithiasis) affects 3-5% of the population and is often associated with hypercalciuria. Hypercalciuric nephrolithiasis is a familial disorder in over 35% of patients and may occur as a monogenic disorder that is more likely to manifest itself in ...

Posted in Uncategorized | No Comments »

The kidney in leptospirosis.

May 1st, 2008
The kidney in leptospirosis. Leptospirosis is a worldwide zoonosis. Typically, patients are young men, although children can be affected. In children, this disease causes mainly alterations of sensorium. Acute renal failure and jaundice (Weil\'s syndrome) are less common in children than in adults. The main renal ...

Posted in Uncategorized | No Comments »

Saccharomyces boulardii prevents oral-poliovirus vaccine-induced IgA nephropathy in mice.

May 1st, 2008
Saccharomyces boulardii prevents oral-poliovirus vaccine-induced IgA nephropathy in mice. Immunoglobulin A nephropathy (IgAN) is associated with mucosal IgA defect. Probiotics regulate specific and innate immunity. We evaluated the effect of Saccharomyces boulardii on experimental IgAN in mice. Four groups of BALB/c mice (eight for each) were ...

Posted in Uncategorized | No Comments »

Reversal of experimental renal fibrosis by BMP7 provides insights into novel therapeutic strategies

May 1st, 2008
Reversal of experimental renal fibrosis by BMP7 provides insights into novel therapeutic strategies for chronic kidney disease. Bone morphogenic protein-7 (BMP7) is a morphogen that is important for kidney development and which is also an integral part of the kidney\'s physiological response to repair of acute ...

Posted in Uncategorized | No Comments »

Glomerular tip changes in childhood minimal change nephropathy.

May 1st, 2008
Glomerular tip changes in childhood minimal change nephropathy. Segmental glomerular lesions at the tubular opening, or tip changes, are found in the renal biopsies of adults in many disorders, including some initially considered to show minimal change nephropathy. The hypothesis was that similar tip changes occurred ...

Posted in Uncategorized | No Comments »

Oral-ibuprofen-induced acute renal failure in a preterm infant.

May 1st, 2008
Oral-ibuprofen-induced acute renal failure in a preterm infant. The side effects of indomethacin for ductal closure in preterm neonates (e.g. increased incidence of necrotizing enterocolitis, decreased cerebral blood volume and transient renal failure) have led clinicians to seek a safer alternative. Intravenous indomethacin and ibuprofen appear ...

Posted in Uncategorized | No Comments »

Virgins in the wild: mating status affects the behavior of a parasitoid foraging in the field.

May 1st, 2008
Virgins in the wild: mating status affects the behavior of a parasitoid foraging in the field. In haplodiploid organisms, virgin females can produce offspring, albeit only sons. They may therefore face a trade-off between either: (1) searching for hosts and producing sons immediately; or (2) searching ...

Posted in Uncategorized | No Comments »

Beyond the reaction progress variable: the meaning and significance of isotopic incorporation data.

May 1st, 2008
Beyond the reaction progress variable: the meaning and significance of isotopic incorporation data. Ecologists conduct isotopic incorporation experiments to determine the residence time of various stable isotopes in animal tissues. These experiments permit determining the time window through which isotopic ecologists perceive the course of diet ...

Posted in Uncategorized | No Comments »

Diversification of the barley and wheat blt101/wpi6 promoters by the Xumet element without affecting

May 1st, 2008
Diversification of the barley and wheat blt101/wpi6 promoters by the Xumet element without affecting stress responsiveness. BLT101-family plasma membrane proteins are found in a wide range of organisms from bacteria to nematodes and are involved in the regulation of cellular cation concentration under stress conditions. A ...

Posted in Uncategorized | No Comments »

Global consequences of phosphatidylcholine reduction in Bradyrhizobium japonicum.

May 1st, 2008
Global consequences of phosphatidylcholine reduction in Bradyrhizobium japonicum. Phosphatidylcholine (PC) is the major phospholipid in eukaryotic membranes. In contrast, it is found in only a limited number of bacteria including members of the Rhizobiales. Here, PC is required for pathogenic and symbiotic plant-microbe interactions, as shown ...

Posted in Uncategorized | No Comments »

Modification of a human monoclonal antibody Fab fragment specific for Plasmodium falciparum 19-kDa C

May 1st, 2008
Modification of a human monoclonal antibody Fab fragment specific for Plasmodium falciparum 19-kDa C-terminal merozoite surface protein 1 by site-directed mutagenesis. We recently produced human monoclonal antibody Fab fragments specific for the 19-kDa C-terminal merozoite surface protein 1 of Plasmodium falciparum in a bacterial expression system. ...

Posted in Uncategorized | No Comments »

Differential expression of cancer-related genes by single and permanent exposure to bone morphogenet

May 1st, 2008
Differential expression of cancer-related genes by single and permanent exposure to bone morphogenetic protein 2. PURPOSE: Bone morphogenetic proteins (BMPs) are multifunctional regulators of various cell functions. The BMP-signalling network plays a pivotal role during embryogenesis and tumorigenesis. BMPs, e.g. BMP-2 exert their biological function in ...

Posted in Uncategorized | No Comments »

Identification of transgelin as a potential novel biomarker for gastric adenocarcinoma based on prot

May 1st, 2008
Identification of transgelin as a potential novel biomarker for gastric adenocarcinoma based on proteomics technology. PURPOSE: To find a biomarker for gastric adenocarcinomas (GA). METHODS: Ten protein expression profiles of GA and paired non-neoplastic mucosa tissues were analyzed by two-dimensional gel electrophoresis. Forty-two protein spots that ...

Posted in Uncategorized | No Comments »