Medical and Biomedical Researches

The impact of nutrition intervention on quality of life in pre-dialysis chronic kidney disease patie

July 3rd, 2008
The impact of nutrition intervention on quality of life in pre-dialysis chronic kidney disease patients. BACKGROUND & AIMS: Uraemic symptoms as a result of reduced kidney function may impact on an individual\'s functional and nutritional status. This study aims to investigate whether providing individualised nutritional counselling ...

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[Genetic iron overloads and hepatic insulin-resistance iron overload syndrome: An update.]

July 3rd, 2008
[Genetic iron overloads and hepatic insulin-resistance iron overload syndrome: An update.] Hepcidin inhibits intestinal absorption of iron through internalisation of ferroportin. Its discovery helps to better understand the genetic iron overloads. The insulin resistance-hepatic iron overload (IR-HIO) - also coined as the dysmetabolic iron overload syndrome ...

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[Amyloid neuropathy resulting from an unknown protein.]

July 3rd, 2008
[Amyloid neuropathy resulting from an unknown protein.] Amyloid neuropathy is related to acquired or hereditary forms of amyloidosis resulting from transthyretin variants. We reported a 42-year-old man suffering from a peripheral neuropathy not related to transthyretin mutations. Mass spectrometry may be useful to identify this rare ...

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[Near a biological diagnosis of Alzheimer’s disease and related disorders.]

July 3rd, 2008
[Near a biological diagnosis of Alzheimer\'s disease and related disorders.] PURPOSE: To review the current concepts in the biological diagnosis of Alzheimer\'s disease (AD) and related disorders. CURRENT KNOWLEDGE AND KEY POINTS: As new therapeutics specific of AD may be available soon, early diagnosis of AD ...

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[Peripheral and bone marrow plasmacytosis in dengue fever: Report of a case.]

July 3rd, 2008
[Peripheral and bone marrow plasmacytosis in dengue fever: Report of a case.] We report a case of dengue fever with plasma cells in the blood (3980 per cubic millimeter) and bone marrow (30%) in a 55-year-old woman hospitalized for fever, arthralgias and thrombocytopenia (66,000 per cubic ...

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[The management of thrombosis in the antiphospholipid antibody syndrome: Insights from recent clinic

July 3rd, 2008
[The management of thrombosis in the antiphospholipid antibody syndrome: Insights from recent clinical trials and remaining unsolved issues.] The antithrombotic therapy of the antiphospholipid syndrome (APS) has long been based on an empirical strategy. In the absence of appropriate randomised controlled trials, data of retrospective cohort ...

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Examination of growth inhibitory properties of synthetic chalcones for which antibacterial activity

July 3rd, 2008
Examination of growth inhibitory properties of synthetic chalcones for which antibacterial activity was predicted. A large series of chalcones were synthesized and studied against Staphylococcus aureus and Escherichia coli. Chalcones were either unsubstituted in ring A or possessed 4\'-chloro or 3\',4\',5\'-trimethoxy groups. Their other ring B ...

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Isolation and cloning of a conotoxin with a novel cysteine pattern from Conus caracteristicus.

July 3rd, 2008
Isolation and cloning of a conotoxin with a novel cysteine pattern from Conus caracteristicus. A new conotoxin, ca16a, containing 8 cysteine residues was purified, sequenced, and cloned from a worm-hunting snail, Conus caracteristicus. This conotoxin is an extremely hydrophilic peptide comprising 34 residues, with 4 acidic ...

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Isolation, characterization and molecular cloning of new temporins from the skin of the North Africa

July 3rd, 2008
Isolation, characterization and molecular cloning of new temporins from the skin of the North African ranid Pelophylax saharica. Temporins are small antimicrobial peptides isolated from North American and Eurasian ranid frogs that are particularly active against Gram-positive bacteria. To date, no temporins have been characterized from ...

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Pardaxin, a fish toxin peptide interaction with a biomimetic phospholipid/polydiacetylene membrane a

July 3rd, 2008
Pardaxin, a fish toxin peptide interaction with a biomimetic phospholipid/polydiacetylene membrane assay. Pardaxin is a fish toxin belonging to the alpha-helical, pore-forming peptide family, used in toxicological and biophysical research to study toxin-cell and -lipid-artificial membranes interactions. We investigated the membrane interaction of two pardaxin analogues ...

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A synthetic peptide corresponding to residues 301-320 of human Wnt-1 promotes PC12 cell adhesion and

July 3rd, 2008
A synthetic peptide corresponding to residues 301-320 of human Wnt-1 promotes PC12 cell adhesion and hippocampal neural stem cell differentiation. Wnt signaling cascades play a crucial role in the maintenance of stem cell niches in many tissues as well as in embryonic patterning and cell-fate determination. ...

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Dietary restraint moderates the effects of food exposure on women’s body and weight satisfaction.

July 3rd, 2008
Dietary restraint moderates the effects of food exposure on women\'s body and weight satisfaction. The influence of dietary restraint and food exposure on body satisfaction was tested. Body and weight satisfaction were measured before and after exposure to either high- or low-caloric food, without actual eating. ...

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An evaluation of eating disorders among a group of Turkish university students.

July 3rd, 2008
An evaluation of eating disorders among a group of Turkish university students. The prevalence of eating disorders has been increasing in the last 20 years, not only in developed countries, but also in less developed countries such as Turkey. This study was conducted among 610 university ...

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Hydrogeochemical behavior of arsenic-enriched groundwater in the deltaic environment: Comparison bet

July 3rd, 2008
Hydrogeochemical behavior of arsenic-enriched groundwater in the deltaic environment: Comparison between two study sites in West Bengal, India. Groundwaters have been collected from deltaic areas of West Bengal (Chakdaha and Baruipur blocks) to record their hydrogeochemical characteristics, and to verify the mechanism of arsenic (As) release. ...

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Are islands the end of the colonization road?

July 3rd, 2008
Are islands the end of the colonization road? Ecologists have, up to now, widely regarded colonization of islands from continents as a one-way journey, mainly because of widely accepted assertions that less diverse island communities are easier to invade. However, continents present large targets and island ...

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Abyssal food limitation, ecosystem structure and climate change.

July 3rd, 2008
Abyssal food limitation, ecosystem structure and climate change. The abyssal seafloor covers more than 50% of the Earth and is postulated to be both a reservoir of biodiversity and a source of important ecosystem services. We show that ecosystem structure and function in the abyss are ...

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[Inquiry among general practitioners’ knowledge regarding clean intermittent self-catheterization.]

July 3rd, 2008
[Inquiry among general practitioners\' knowledge regarding clean intermittent self-catheterization.] INTRODUCTION: Clean intermittent self-catheterization is the recommended mode of bladder voiding in patients with urinary retention. Hence, this procedure should be well known and understood by the general practitioners (GP) who are responsible for monitoring such patients. ...

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The major tegument structural protein VP22 targets areas of dispersed nucleolin and marginalized chr

July 3rd, 2008
The major tegument structural protein VP22 targets areas of dispersed nucleolin and marginalized chromatin during productive herpes simplex virus 1 infection. The herpes simplex virus (HSV) major tegument structural protein VP22 resides in multiple subcellular regions during productive infection. During an analysis of the molecular determinants ...

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A new approach for the purification and characterisation of PA49.5, the main prebiotic of Lactococcu

July 3rd, 2008
A new approach for the purification and characterisation of PA49.5, the main prebiotic of Lactococcus lactis subsp. cremoris. The main autolysin PA49.5, an enzyme that hydrolyzes or destroys the components of a biological endogenous cell or a tissue, was purified 3045 times from the homogenate of ...

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Local control and survival in patients with soft tissue sarcomas treated with limb sparing surgery i

July 3rd, 2008
Local control and survival in patients with soft tissue sarcomas treated with limb sparing surgery in combination with interstitial brachytherapy and external radiation. PURPOSE: The purpose of this study was to evaluate local control, survival and complication rate after treatment of soft tissue sarcoma (STS) with ...

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Environmental protection: applying the precautionary principle and proactive regulation to biotechno

July 3rd, 2008
Environmental protection: applying the precautionary principle and proactive regulation to biotechnology. Biotechnology is a broad field encompassing diverse disciplines from agriculture to zoology. Advances in research are occurring at a rapid pace, and applications that have broad implications socially, economically, ecologically and politically are emerging. Along ...

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Analysis of T-RFLP data using analysis of variance and ordination methods: A comparative study.

July 3rd, 2008
Analysis of T-RFLP data using analysis of variance and ordination methods: A comparative study. The analysis of T-RFLP data has developed considerably over the last decade, but there remains a lack of consensus about which statistical analyses offer the best means for finding trends in these ...

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Fixation procedures for flow cytometric analysis of environmental bacteria.

July 3rd, 2008
Fixation procedures for flow cytometric analysis of environmental bacteria. Analysis of environmental bacteria on the single cell level often requires fixation to store the cells and to keep them in a state as near life-like as possible. Fixation procedures should furthermore counteract the increase of autofluorescence, ...

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Is there a beneficial effect of folic acid on carotid intima-media thickness?

July 3rd, 2008
Is there a beneficial effect of folic acid on carotid intima-media thickness? In a recent article by Fernandez-Miranda et al., it was shown that daily administration of 2.5 mg of folate did not significantly alter carotid-intima media thickness (IMT) in patients with coronary heart disease in ...

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Responses of vascular smooth muscle cells to estrogen are dependent on balance between ERK and p38 M

July 3rd, 2008
Responses of vascular smooth muscle cells to estrogen are dependent on balance between ERK and p38 MAPK pathway activities. OBJECTIVE: To investigate the mechanisms underlying the dual effects of estrogen on vascular smooth muscle cells (VSMC). METHODS: MTT assay, ELISA, flow cytometry and Western analysis were ...

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