Medical and Biomedical Researches

Early diabetic neuropathy: thermal thresholds and intraepidermal nerve fibre density in patients wit

June 27th, 2008
Early diabetic neuropathy: thermal thresholds and intraepidermal nerve fibre density in patients with normal nerve conduction studies. OBJECTIVES : To determine whether neuropathy in diabetic patients with normal nerve conduction studies could be detected by measurements of thermal thresholds and quantification of intraepidermal nerve fibre (IENF) ...

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(11)C-Flumazenil positron emission tomography demonstrates reduction of both global and local cerebr

June 27th, 2008
(11)C-Flumazenil positron emission tomography demonstrates reduction of both global and local cerebral benzodiazepine receptor binding in a patient with Stiff Person Syndrome. Stiff Person Syndrome (SPS) is a rare autoimmune disorder associated with antibodies against glutamic acid decarboxylase (GAD-Ab), the key enzyme in gamma-aminobutyric acid synthesis ...

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Association study of interleukin 2 (IL2) and IL4 with schizophrenia in a Japanese population.

June 27th, 2008
Association study of interleukin 2 (IL2) and IL4 with schizophrenia in a Japanese population. Interleukin 2 (IL-2) and IL-4 are pleiotropic cytokines regulating Th1/Th2 balance and have a regulatory activity in brain function. Thus these cytokines have been implicated in the pathophysiology of schizophrenia. The latest ...

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Age-specific familial risks of anxiety : A nation-wide epidemiological study from Sweden.

June 27th, 2008
Age-specific familial risks of anxiety : A nation-wide epidemiological study from Sweden. OBJECTIVE: Familial risks of anxiety have been assessed in small case-control studies, usually based on reported, but not medically verified, anxiety in family members; thus the degree of familial clustering of these diseases remains ...

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Predicting caregiver burden in first admission psychiatric patients : 2-year follow-up results.

June 27th, 2008
Predicting caregiver burden in first admission psychiatric patients : 2-year follow-up results. OBJECTIVE: The aim of the study was to identify the best predictors of the course of burden during a 2-year follow-up period. The study is part of the Munich 5-year follow-up study in relatives ...

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Suicide attempters: biological stressmarkers and adverse life events.

June 27th, 2008
Suicide attempters: biological stressmarkers and adverse life events. Risk factors for suicidal behaviour include adverse life events as well as biochemical parameters acting, e.g. within the hypothalamic-pituitary-adrenal axis and/or monoaminergic systems. The aim of the present investigation was to study stressful life events and biological stress ...

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Iron states and cognitive abilities in young adults: neuropsychological and neurophysiological asses

June 27th, 2008
Iron states and cognitive abilities in young adults: neuropsychological and neurophysiological assessment. Many investigators found that iron deficiency anemia (IDA) had a great influence on cognitive functions in infants and children. However, studies of such topic in adults are few and controversial. We prospectively assessed the ...

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Toward the delineation of mania subtypes in the French National EPIMAN-II Mille Cohort : Comparisons

June 27th, 2008
Toward the delineation of mania subtypes in the French National EPIMAN-II Mille Cohort : Comparisons with prior cluster analytic investigations. BACKGROUND: Knowledge about psychopathologic presentations of mania in current clinical practice has to be refined in order to improve diagnosis and treatment. METHODS: One thousand ninety ...

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Tyrosine hydroxylase immunoreactivity in the locus coeruleus is elevated in violent suicidal depress

June 27th, 2008
Tyrosine hydroxylase immunoreactivity in the locus coeruleus is elevated in violent suicidal depressive patients. Our postmortem study aimed to determine the impact of suicide on the number of noradrenergic neurons of the locus coeruleus (LC) in suicidal depressive patients. Noradrenergic neurons were shown by immunostaining tyrosine ...

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The QTc interval and its dispersion in patients receiving two atypical antipsychotics.

June 27th, 2008
The QTc interval and its dispersion in patients receiving two atypical antipsychotics. OBJECTIVE: Treatment with atypical antipsychotics may prolong the rate-corrected Q-T interval (QTc) on electrocardiogram and increase the risk of dangerous ventricular arrhythmias. Polytherapy with atypical antipsychotics is becoming common, but the effect of this ...

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Calcium-Independent Phospholipase A(2) in Rabbit Ventricular Myocytes.

June 27th, 2008
Calcium-Independent Phospholipase A(2) in Rabbit Ventricular Myocytes. We have previously reported that the majority of phospholipase A(2) (PLA(2)) activity in rabbit ventricular myocytes is membrane-associated, calcium-independent (iPLA(2)), selective for arachidonylated plasmalogen phospholipids and inhibited by the iPLA(2)-selective inhibitor bromoenol lactone (BEL). Here, we identified the presence ...

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The infochemical effect-a new chapter in ecotoxicology.

June 27th, 2008
The infochemical effect-a new chapter in ecotoxicology. BACKGROUND, AIM, AND SCOPE: Organisms use chemical cues in their surrounding, so-called infochemicals, as important source of information about their biotic and abiotic environment. The scope of this work is to transfer the knowledge on infochemicals obtained in chemical ...

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Antifungal activity of 25-azalanosterol against Candida species.

June 27th, 2008
Antifungal activity of 25-azalanosterol against Candida species. The antifungal properties of 25-azalanosterol was investigated. Compared to normal antifungal reagents, fluoconazole, clotrimazole and voriconazole, it exhibited significant anti-Candida activity (the minimum inhibitory concentration [MIC] ranges were 0.125-8, 0.5-8 and 0.5-32 microg/mL against C. albicans, C. krusei and ...

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Capuchin monkeys (Cebus apella) respond to video images of themselves.

June 27th, 2008
Capuchin monkeys (Cebus apella) respond to video images of themselves. Many studies have used mirror-image stimulation in attempts to find self-recognition in monkeys. However, very few studies have presented monkeys with video images of themselves; the present study is the first to do so with capuchin ...

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Comparing responses to novel objects in wild baboons (Papio ursinus) and geladas (Theropithecus gela

June 27th, 2008
Comparing responses to novel objects in wild baboons (Papio ursinus) and geladas (Theropithecus gelada). Behavioral flexibility is considered by some to be one of the hallmarks of advanced cognitive ability. One measure of behavioral flexibility is how subjects respond to novel objects. Despite growing interest in ...

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Thrombotic thrombocytopenic purpura related to severe ADAMTS13 deficiency in children.

June 27th, 2008
Thrombotic thrombocytopenic purpura related to severe ADAMTS13 deficiency in children. Thrombotic thrombocytopenic purpura (TTP) related to a severely deficient activity of the von Willebrand factor cleaving protease, ADAMTS (A Disintegrin And Metalloprotease with ThromboSpondin type 1 repeats) 13, is a life-threatening event, the onset of which ...

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Detection and incidence of anomalies associated with hypospadias.

June 27th, 2008
Detection and incidence of anomalies associated with hypospadias. Hypospadias has been associated with synchronous congenital anomalies, especially in the urogenital system, and routine screening of patients with hypospadias has been advocated. In recent years, ultrasound (US) has replaced intravenous pyelography (IVP) as the primary screening test ...

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Effect of sodium overload on renal function of offspring from diabetic mothers.

June 27th, 2008
Effect of sodium overload on renal function of offspring from diabetic mothers. The aim if this study was to evaluate the effect of sodium overload on blood pressure and renal function in the offspring of diabetic rat mothers. Diabetes was induced with a single dose of ...

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Small-scale coexistence of two mouse lemur species (Microcebus berthae and M. murinus) within a homo

June 27th, 2008
Small-scale coexistence of two mouse lemur species (Microcebus berthae and M. murinus) within a homogeneous competitive environment. Understanding the co-occurrence of ecologically similar species remains a puzzling issue in community ecology. The species-rich mouse lemurs (Microcebus spec.) are distributed over nearly all remaining forest areas of ...

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Temperature is the key factor explaining interannual variability of Daphnia development in spring: a

June 27th, 2008
Temperature is the key factor explaining interannual variability of Daphnia development in spring: a modelling study. Plankton succession during spring/early summer in temperate lakes is characterised by a highly predictable pattern: a phytoplankton bloom is grazed down by zooplankton (Daphnia) inducing a clear-water phase. This sequence ...

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Complexity and idiosyncrasy in the responses of algae to disturbance in mono- and multi-species asse

June 27th, 2008
Complexity and idiosyncrasy in the responses of algae to disturbance in mono- and multi-species assemblages. There is considerable debate about whether stability (e.g. inertia) of an assemblage, or of individuals in an assemblage, is positively associated with the number of species or whether there are idiosyncratic ...

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Semaphorin-3A and its receptor neuropilin-1 are predominantly expressed in endothelial cells along t

June 27th, 2008
Semaphorin-3A and its receptor neuropilin-1 are predominantly expressed in endothelial cells along the rostral migratory stream of young and adult mice. In the adult brain, neuroblasts originating in the subventricular zone migrate through the rostral migratory stream to the olfactory bulb. While migrating, neuroblasts undergo progressive ...

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Endoplasmic reticulum stress activates the expression of a sub-group of protein disulfide isomerase

June 27th, 2008
Endoplasmic reticulum stress activates the expression of a sub-group of protein disulfide isomerase genes and AtbZIP60 modulates the response in Arabidopsis thaliana. Proteins entering the secretory pathway of eukaryotic cells are folded into their native structures in the endoplasmic reticulum (ER). Disruption of protein folding causes ...

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The detection and quantification of a digenean infection in the snail host with special emphasis on

June 27th, 2008
The detection and quantification of a digenean infection in the snail host with special emphasis on Fasciola sp. In this review, ten methods used to study digenean infections in their intermediate hosts were compared to determine which one should be used either in the field or ...

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Comparison of different techniques for the detection of genetic risk-identifying chromosomal gains a

June 27th, 2008
Comparison of different techniques for the detection of genetic risk-identifying chromosomal gains and losses in neuroblastoma. Neuroblastoma (NB) is a pediatric neoplasia that shows complex combinations of acquired genetic aberrations. The specific genes and the molecular mechanisms responsible for development and progression of NB remain poorly ...

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