Medical and Biomedical Researches

The influence of platelet activating factor on the effects of platelet agonists and antiplatelet age

June 27th, 2008
The influence of platelet activating factor on the effects of platelet agonists and antiplatelet agents in vitro. We assessed the effect of the intercellular mediator of inflammation, platelet activating factor (PAF), on platelet function. The interaction between PAF and the platelet agonists ADP, thrombin and convulxin ...

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Prolonged survival after multifocal brain radiation necrosis associated with whole brain radiation f

June 27th, 2008
Prolonged survival after multifocal brain radiation necrosis associated with whole brain radiation for brain metastases: case report. Radiation necrosis of the brain is a well documented adverse effect of radiation therapy. The authors report an unusual case of relapsing multifocal radiation necrosis following whole brain radiation ...

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Bifocal mixed germ-cell tumor with growing teratoma syndrome and metachronous mature metastases: cas

June 27th, 2008
Bifocal mixed germ-cell tumor with growing teratoma syndrome and metachronous mature metastases: case report. The authors report the case of a 16-year-old male who presented with a bifocal diencephalic tumor arising both in the neurohypophysis and the pineal region with hydrocephalus. The histological diagnosis obtained during ...

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Mycobacterium peregrinum: bactericidal activity of antibiotics alone and in combination.

June 27th, 2008
Mycobacterium peregrinum: bactericidal activity of antibiotics alone and in combination. Mycobacterium peregrinum is a rapidly growing mycobacterium that is occasionally associated with disease at different locations. At present, little information is available on antibiotic activity against this microorganism. For this reason, we have carried out a ...

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Molecular characteristics of serotype 3 Streptococcus pneumoniae isolates among community-acquired p

June 27th, 2008
Molecular characteristics of serotype 3 Streptococcus pneumoniae isolates among community-acquired pneumonia patients in Japan. In order to understand the spread of the erythromycin-resistant serotype 3 Streptococcus pneumoniae clone in Japan, we have assessed the molecular characteristics of this clone. Among 156 S. pneumoniae isolates recovered from ...

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Descending necrotizing mediastinitis secondary to retropharyngeal abscess in a child.

June 27th, 2008
Descending necrotizing mediastinitis secondary to retropharyngeal abscess in a child. We report herein of a 6-year-old boy with descending necrotizing mediastinitis (DNM) secondary to retropharyngeal abscess, who was successfully treated by the administration of antibiotics. DNM is very rare in children, and surgical drainage of the ...

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Chronic Helicobacter pylori infection is associated with peripheral arterial disease.

June 27th, 2008
Chronic Helicobacter pylori infection is associated with peripheral arterial disease. It is reported that Helicobacter pylori infection is associated with coronary atherosclerosis both epidemiologically and pathogenetically, but no conclusions have yet been reached. Therefore, we investigated the relationship between H. pylori infection and peripheral arterial disease ...

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Usefulness of procalcitonin serum level for the discrimination of severe sepsis from sepsis: a multi

June 27th, 2008
Usefulness of procalcitonin serum level for the discrimination of severe sepsis from sepsis: a multicenter prospective study. Procalcitonin serum level has been recommended as a new marker of bacterial infectious diseases. The aim of this prospective, multicenter study was to determine the clinical usefulness of procalcitonin ...

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Susceptibility of clinical isolates of Pseudomonas aeruginosa in the Northern Kyushu district of Jap

June 27th, 2008
Susceptibility of clinical isolates of Pseudomonas aeruginosa in the Northern Kyushu district of Japan to carbapenem antibiotics, determined by an integrated concentration method: evaluation of the method based on Monte Carlo simulation. In empirical antibacterial therapy, regional surveillance is expected to yield important information for the ...

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Association of hyperhomocysteinemia and Chlamydia pneumoniae infection with carotid atherosclerosis

June 27th, 2008
Association of hyperhomocysteinemia and Chlamydia pneumoniae infection with carotid atherosclerosis and coronary artery disease in Japanese patients. An elevated plasma level of homocysteine (Hcy) and infection by Chlamydia pneumoniae (C. pneumoniae) have been suggested as independent risk factors for carotid atherosclerosis (CA) and coronary artery disease ...

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Nosocomial diarrhea caused by Clostridium perfringens in the Tsukuba-Tsuchiura district, Japan.

June 27th, 2008
Nosocomial diarrhea caused by Clostridium perfringens in the Tsukuba-Tsuchiura district, Japan. We examined the incidence of nosocomial diarrhea caused by Clostridium perfringens enterotoxin (CPEnt) in three tertiary hospitals in the Tsukuba-Tsuchiura district, Japan. In addition, isolated strains were genomically characterized. Among 294 stool specimens submitted for ...

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Remarkably high prevalence of fts I gene mutations in Haemophilus influenzae isolates from upper res

June 27th, 2008
Remarkably high prevalence of fts I gene mutations in Haemophilus influenzae isolates from upper respiratory tract infections in children of the Sapporo district, Japan. Recently, the frequency of isolation of beta-lactamase-negative ampicillin resistant (BLNAR) strains of Haemophilus influenzae in Japanese children has been increasing rapidly. Drug ...

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The relationship between the daily dosage of the carbapenem meropenem (MEPM) and MEPM-resistant Pseu

June 27th, 2008
The relationship between the daily dosage of the carbapenem meropenem (MEPM) and MEPM-resistant Pseudomonas aeruginosa. Pseudomonas aeruginosa is a pathogen which is known to be responsible for nosocomial infection. The appropriate use of antibiotics has become important for preventing the spread of drug-resistant P. aeruginosa. In ...

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Five-day oral cefditoren pivoxil versus 10-day oral amoxicillin for pediatric group A streptococcal

June 27th, 2008
Five-day oral cefditoren pivoxil versus 10-day oral amoxicillin for pediatric group A streptococcal pharyngotonsillitis. We prospectively compared the efficacy of oral cefditoren-pivoxil and conventional oral amoxicillin for pharyngotonsillitis caused by group A streptococcus in children. Either oral cefditoren-pivoxil (3 mg/kg t.i.d. for 5 days) or amoxicillin ...

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Comparative study of 5-day cefcapene-pivoxil and 10-day amoxicillin or cefcapene-pivoxil for treatme

June 27th, 2008
Comparative study of 5-day cefcapene-pivoxil and 10-day amoxicillin or cefcapene-pivoxil for treatment of group A streptococcal pharyngitis in children. In order to compare the bacteriological and clinical efficacy and safety of cefcapene-pivoxil (CFPN-PI) for 5 days, CFPN-PI for 10 days, and amoxicillin (AMPC) for 10 days ...

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Ocular distribution of intravenously administered micafungin in rabbits.

June 27th, 2008
Ocular distribution of intravenously administered micafungin in rabbits. The ocular distribution of micafungin (MCFG), which has antifungal activity against Candida and Aspergillus species, was followed after the systemic administration of MCFG in rabbits. After MCFG (10 mg/kg) plus fluconazole (FLCZ; 10 mg/kg) was administered intravenously, the ...

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Analysis of amino acid sequences of penicillin-binding protein 2 in clinical isolates of Neisseria g

June 27th, 2008
Analysis of amino acid sequences of penicillin-binding protein 2 in clinical isolates of Neisseria gonorrhoeae with reduced susceptibility to cefixime and ceftriaxone. Neisseria gonorrhoeae strains with reduced susceptibility to cefixime and ceftriaxone, with minimum inhibitory concentrations (MICs) of cefixime of 0.125-0.25 mug/ml and ceftriaxone of 0.031-0.125 ...

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Effects of artesunate-cotrimoxazole and amodiaquine-artesunate against asexual and sexual stages of

June 27th, 2008
Effects of artesunate-cotrimoxazole and amodiaquine-artesunate against asexual and sexual stages of Plasmodium falciparum malaria in Nigerian children. The activities of artesunate-cotrimoxazole and artesunate-amodiaquine combinations against asexual-and sexual-stage parasites were evaluated in 182 Nigerian children with uncomplicated Plasmodium falciparum malaria. One hundred and twenty-one children received artesunate-cotrimoxazole ...

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Clinical bacteriology and immunology in acute otitis media in children.

June 27th, 2008
Clinical bacteriology and immunology in acute otitis media in children. Acute otitis media (AOM) is the most common disease seen in childhood. Streptococcus pneumoniae, non-typeable Haemophilus influenzae (NTHi), and Moraxella catarrhalis are the most frequent pathogens of all AOM episodes. The high prevalence of drug-resistant pathogens ...

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Visual disturbance comorbid with hallucination caused by voriconazole in the Japanese population.

June 27th, 2008
Visual disturbance comorbid with hallucination caused by voriconazole in the Japanese population. Voriconazole (VRCZ) has a curious visual adverse event that is completely reversible, but its mechanism has not been fully addressed. We observed 20 consecutive patients treated with VRCZ after chemotherapy for hematological malignancy. Six ...

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Long-term Results With a Lateral Unicondylar Replacement.

June 27th, 2008
Long-term Results With a Lateral Unicondylar Replacement. While the literature suggests lateral unicondylar knee arthroplasty (UKA) improves function in the short- and medium-term, it is less clear on longer-term function. We asked (1) whether lateral UKA improved longer-term Knee Society scores and return to previous activity ...

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An Integrated View of Empathy: Psychology, Philosophy, and Neuroscience.

June 27th, 2008
An Integrated View of Empathy: Psychology, Philosophy, and Neuroscience. In this paper, we will examine and untangle a conflict mainly between a developmental psychologist, Martin Hoffman and a social psychologist, Daniel Batson. According to Hoffman, empathic distress, a vicarious feeling through empathy, is transformed into an ...

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Natural Orifice Transluminal Endoscopic Gastric Bypass Performed in a Cadaver.

June 27th, 2008
Natural Orifice Transluminal Endoscopic Gastric Bypass Performed in a Cadaver. Natural orifice transluminal surgery (NOTES) offers a new option for abdominal surgery. However, despite the initial interest and enthusiasm for its potential advantages, NOTES has some major drawbacks which include the purposeful injury to an organ ...

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Inferior Vena Cava Syndrome and Morbid Obesity.

June 27th, 2008
Inferior Vena Cava Syndrome and Morbid Obesity. A case is reported of inferior vena cava syndrome in a patient with extreme obesity (BMI: >70 kg/m(2)), treated at a public hospital. The inferior vena cava obstruction was diagnosed during an attempt at inferior vena cava filter percutaneous ...

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Ursodeoxycholic Acid in the Prevention of Gallstone Formation after Bariatric Surgery: A Meta-analys

June 27th, 2008
Ursodeoxycholic Acid in the Prevention of Gallstone Formation after Bariatric Surgery: A Meta-analysis. BACKGROUND: Rapid weight loss increases risk for gallstone formation. Prophylactic cholecystectomy is difficult. Several small trials have shown that ursodeoxycholic acid (UDCA) may prevent gallstone formation after bariatric surgery. The aim of this ...

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