Medical and Biomedical Researches

Gender-specific development of auditory information processing in children: An ERP study.

June 28th, 2008
Gender-specific development of auditory information processing in children: An ERP study. OBJECTIVES: The aim of the present study was to evaluate the effects of gender on sensory and cognitive information processing in children by analyzing auditory event-related potentials (ERPs). The major questions were: (1) do ERPs ...

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Characterization of naturally occurring parainfluenza virus type 2 (hPIV-2) variants.

June 28th, 2008
Characterization of naturally occurring parainfluenza virus type 2 (hPIV-2) variants. BACKGROUND: Human parainfluenza viruses (hPIV) are respiratory pathogens responsible for upper and lower respiratory tract infections. In most labs, the clinical diagnosis of hPIV is routinely done using techniques based on the detection of viral antigens ...

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Building an inter-organizational communication network and challenges for preserving interoperabilit

June 28th, 2008
Building an inter-organizational communication network and challenges for preserving interoperability. BACKGROUND: The ideal scenario for information technology to bridge information gaps between primary and secondary healthcare and to improve the quality of healthcare in the medication process is to build an interoperable communication network. This type ...

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Establishment of the comet assay in the freshwater snail Biomphalaria glabrata (Say, 1818).

June 28th, 2008
Establishment of the comet assay in the freshwater snail Biomphalaria glabrata (Say, 1818). The single cell gel eletrophoresis or the comet assay was established in the freshwater snail Biomphalaria glabrata. For detecting DNA damage in circulating hemocytes, adult snails were irradiated with single doses of 2.5, ...

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Genotoxic damage in polychaetes: A study of species and cell-type sensitivities.

June 28th, 2008
Genotoxic damage in polychaetes: A study of species and cell-type sensitivities. The marine environment is becoming increasingly contaminated by environmental pollutants with the potential to damage DNA, with marine sediments acting as a sink for many of these contaminants. Understanding genotoxic responses in sediment-dwelling marine organisms, ...

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Niche-specific gene expression during C. albicans infection.

June 28th, 2008
Niche-specific gene expression during C. albicans infection. Infection by the opportunistic pathogen Candida albicans may occur in virtually any organ of the human host. Studies of C. albicans gene expression during experimental infection reveal that different stress responses are mounted during different types of infection, presumably ...

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Aspergillus fumigatus: virulence genes in a street-smart mold.

June 28th, 2008
Aspergillus fumigatus: virulence genes in a street-smart mold. Infections with the filamentous fungus Aspergillus fumigatus are among the most devastating of the systemic mycoses. Unlike most primary pathogens, which possess virulence traits that developed in association with a host organism, evidence suggests that the virulence of ...

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The value of proteasome inhibition in cancer Can the old drug, disulfiram, have a bright new future

June 28th, 2008
The value of proteasome inhibition in cancer Can the old drug, disulfiram, have a bright new future as a novel proteasome inhibitor? The major approach to the development of anticancer drugs involves searching for new compounds, efficient against malignancies, which are not, as yet, used clinically. ...

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Overexpression of A-kinase anchoring protein 12A activates sterol regulatory element binding protein

June 28th, 2008
Overexpression of A-kinase anchoring protein 12A activates sterol regulatory element binding protein-2 and enhances cholesterol efflux in hepatic cells. A-kinase anchoring protein 12 (AKAP12) is known to function as a scaffold protein and as a putative tumor suppressor. However, little is known about the biological role ...

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Involvement of the serotonin system in l-dopa-induced dyskinesias.

June 28th, 2008
Involvement of the serotonin system in l-dopa-induced dyskinesias. The ability of l-dopa to relieve the motor impairments in Parkinson\'s disease patients declines over time and side-effects, such as dyskinesias, appear - limiting the use of the drug in the advanced stage of the disease. Serotonergic neurons ...

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The MPTP mouse model: Cues on DA release and neural stem cell restorative role.

June 28th, 2008
The MPTP mouse model: Cues on DA release and neural stem cell restorative role. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is known to cause parkinsonism in humans and this fact is a major incentive for using this toxin as an animal model to study the pathogenesis of Parkinson\'s disease (PD). ...

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A meningitis case due to Stenotrophomonas maltophilia and review of the literature.

June 28th, 2008
A meningitis case due to Stenotrophomonas maltophilia and review of the literature. Stenotrophomonas maltophilia (formerly Xanthomonas maltophilia) is a Gram-negative bacillus increasingly associated with serious nosocomial infections. Here, we describe a 30-year-old male patient who developed meningitis associated with this organism after several neurosurgical procedures. A ...

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Molecular cloning and characterization of a novel cold-active beta-1,4-d-mannanase from the Antarcti

June 28th, 2008
Molecular cloning and characterization of a novel cold-active beta-1,4-d-mannanase from the Antarctic springtail, Cryptopygus antarcticus. A cDNA encoding a beta-1,4-d-mannanase (CaMan) was identified among the expressed sequence tags (ESTs) of the Antarctic springtail, Cryptopygus antarcticus. The open reading frame consisted of 1149 bp encoding 382 amino ...

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Heat shock proteins (Hsp70) and water content in the estivating Mediterranean Grunt Snail (Cantareus

June 28th, 2008
Heat shock proteins (Hsp70) and water content in the estivating Mediterranean Grunt Snail (Cantareus apertus). Pulmonate land snails often are able to estivate to survive dry hot seasons were water and food are scarce. The aperture of the shell is closed with an epiphragm, and metabolism ...

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Effect of anoxia on the electroretinogram of three anoxia-tolerant vertebrates.

June 28th, 2008
Effect of anoxia on the electroretinogram of three anoxia-tolerant vertebrates. To survive anoxia, neural ATP levels have to be defended. Reducing electrical activity, which accounts for 50% or more of neural energy consumption, should be beneficial for anoxic survival. The retina is a hypoxia sensitive part ...

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The dependence on magnetic field strength of correlated internal gradient relaxation time distributi

June 28th, 2008
The dependence on magnetic field strength of correlated internal gradient relaxation time distributions in heterogeneous materials. Magnetic susceptibility differences in porous media produce local gradients within the pore space. At high magnetic fields, these inhomogeneities have the potential to greatly affect nuclear magnetic resonance measurements. We ...

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Magnetic resonance imaging and proton magnetic resonance spectroscopy of the brain in the diagnostic

June 28th, 2008
Magnetic resonance imaging and proton magnetic resonance spectroscopy of the brain in the diagnostic evaluation of developmental delay. AIM: To assess the contribution of MRI and proton spectroscopy (1HMRS) in establishing an etiological diagnosis in children with developmental delay (DD) and to assess whether the chance ...

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Ischaemic and haemorrhagic stroke in the dog.

June 28th, 2008
Ischaemic and haemorrhagic stroke in the dog. Cerebrovascular disease results from any pathological process of the blood vessels supplying the brain. Stroke, characterised by its abrupt onset, is the third leading cause of death in humans. This rare condition in dogs is increasingly being recognised with ...

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A genome-based analysis of amino acid metabolism in the biotrophic plant pathogen Ustilago maydis.

June 28th, 2008
A genome-based analysis of amino acid metabolism in the biotrophic plant pathogen Ustilago maydis. Amino acid, nitrogen and sulfur metabolism play critical roles in the growth and development of fungal pathogens both in and outside of the host. The genome sequence of Ustilago maydis provides an ...

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How to Introduce Carotid Angioplasty without Compromising Patient Safety.

June 28th, 2008
How to Introduce Carotid Angioplasty without Compromising Patient Safety. Carotid angioplasty with stenting (CAS) is increasingly being used in the treatment of extracranial carotid disease and numerous studies have demonstrated its feasibility. However, the exact role of CAS in the treatment of carotid stenosis and its ...

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Accelerated cognitive aging in diabetic rats is prevented by lowering corticosterone levels.

June 28th, 2008
Accelerated cognitive aging in diabetic rats is prevented by lowering corticosterone levels. Diabetes and normal aging are both characterized by increases in levels of glucocorticoids. Because long-term exposure to elevated glucocorticoids can be detrimental to hippocampal function, we evaluated the performance of young diabetic rats in ...

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NF-kappaB inhibitors induce lytic cytotoxicity in Epstein-Barr virus-positive nasopharyngeal carcino

June 28th, 2008
NF-kappaB inhibitors induce lytic cytotoxicity in Epstein-Barr virus-positive nasopharyngeal carcinoma cells. Epstein-Barr virus (EBV) infection in tumor cells is generally restricted to the latent forms of viral infection. Switching the latent form of viral infection into the lytic form may induce tumor cell death. An important ...

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Comparative analysis of gene expression profiles between the normal human cartilage and the one with

June 28th, 2008
Comparative analysis of gene expression profiles between the normal human cartilage and the one with endemic osteoarthritis. OBJECTIVE: To investigate the differences in gene expression profiles of adult articular cartilage with endemic osteoarthritis (OA), Kashin-Beck disease (KBD), and the same regions in the normal joint. METHODS: ...

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Molecular phylogenetics of the Pectinidae (Mollusca: Bivalvia) and effect of increased taxon samplin

June 28th, 2008
Molecular phylogenetics of the Pectinidae (Mollusca: Bivalvia) and effect of increased taxon sampling and outgroup selection on tree topology. Evolutionary relationships of the Pectinidae were examined using two mitochondrial genes (12S rRNA, 16S rRNA) and one nuclear gene (Histone H3) for 46 species. Outgroup taxa from ...

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Functional grouping and cortical-subcortical interactions in emotion: A meta-analysis of neuroimagin

June 28th, 2008
Functional grouping and cortical-subcortical interactions in emotion: A meta-analysis of neuroimaging studies. We performed an updated quantitative meta-analysis of 162 neuroimaging studies of emotion using a novel multi-level kernel-based approach, focusing on locating brain regions consistently activated in emotional tasks and their functional organization into distributed ...

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