Cyclooxygenase-2 expression in primary and recurrent pterygium.
June 28th, 2008Cyclooxygenase-2 expression in primary and recurrent pterygium. Background: Pterygia are common, benign, fibrovascular, and infiltrative processes of the corneo-conjunctival junction of unknown pathogenesis. Cyclooxygenase-2 (COX-2) mediates the rate-limiting step in arachidonic acid metabolism. Extensive evidence indicates that the COX-2 prostanoid pathway is involved in inflammation. The ...