Medical and Biomedical Researches

The timing of the involvement of the frontal eye fields and posterior parietal cortex in visual sear

June 28th, 2008
The timing of the involvement of the frontal eye fields and posterior parietal cortex in visual search. The frontal eye fields (FEFs) and posterior parietal cortex (PPC) are important for target detection in conjunction visual search but the relative timings of their contribution have not been ...

Posted in for26cat | No Comments »

Inhibitory effect of zinc on hypoxic HIF-1 activation in astrocytes.

June 28th, 2008
Inhibitory effect of zinc on hypoxic HIF-1 activation in astrocytes. Hypoxia-inducible factor-1 (HIF-1) regulates the expression of neuroprotective genes such as erythropoietin (EPO). We investigated the mechanism by which zinc, an excitotoxin-like metal, regulates HIF-1 under hypoxic conditions in astrocytes. In hypoxic LN215 cells, HIF-1alpha stabilized ...

Posted in for26cat | No Comments »

Antinociceptive action of GLYX-13: an N-methyl-D-aspartate receptor glycine site partial agonist.

June 28th, 2008
Antinociceptive action of GLYX-13: an N-methyl-D-aspartate receptor glycine site partial agonist. Inhibition of N-methyl-D-aspartate (NMDA)-mediated neurotransmission has been demonstrated to provide antinociceptive actions in a number of animal models of tonic and neuropathic pain. However, both competitive and noncompetitive NMDA receptor antagonists are ataxic at analgesic ...

Posted in for26cat | No Comments »

Time estimation in Parkinson’s disease and degenerative cerebellar disease.

June 28th, 2008
Time estimation in Parkinson\'s disease and degenerative cerebellar disease. With functional MRI, we recently identified fronto-cerebellar activations in predicting time to reach a target and basal ganglia activation in velocity estimation, that is, small interval assessment. We now tested these functions in patients with Parkinson\'s disease ...

Posted in for26cat | No Comments »

Low-threshold afferent signalling of viscous loads during voluntary movements of the human digits.

June 28th, 2008
Low-threshold afferent signalling of viscous loads during voluntary movements of the human digits. Humans can discriminate changes in load viscosity during voluntary contractions. The afferent signal origin is unknown. Microneurographic recordings from 83 single low-threshold afferents were made while participants performed triangular ramps either unloaded or ...

Posted in for26cat | No Comments »

Enhanced negative feedback responses in remitted depression.

June 28th, 2008
Enhanced negative feedback responses in remitted depression. Major depressive disorder (MDD) is characterized by hypersensitivity to negative feedback that might involve frontocingulate dysfunction. MDD patients exhibit enhanced electrophysiological responses to negative internal (errors) and external (feedback) cues. Whether this dysfunction extends to remitted depressed (RD) individuals ...

Posted in for26cat | No Comments »

Brain responses to agreement violations of Chinese grammatical aspect.

June 28th, 2008
Brain responses to agreement violations of Chinese grammatical aspect. Grammatical aspect captures ways in which a language uses grammatical markers to describe the temporal structure of an event. An event-related potential experiment was conducted to investigate event-related potential correlates of agreement violations of Chinese grammatical aspect. ...

Posted in for26cat | No Comments »

Anxiety vulnerability is associated with altered anterior cingulate response to an affective apprais

June 28th, 2008
Anxiety vulnerability is associated with altered anterior cingulate response to an affective appraisal task. The anterior cingulate cortex (ACC) is critically involved not only in affective and anxiety processing, but also in error and conflict monitoring. To investigate how anxiety interacts with processing affective ambiguity, 15 ...

Posted in for26cat | No Comments »

The brain proteome profile is highly conserved between Prnp-/- and Prnp+/+ mice.

June 28th, 2008
The brain proteome profile is highly conserved between Prnp-/- and Prnp+/+ mice. The aim of this study is to compare the proteome of Prnp (Zürich I) gene-ablated mouse brains with wild-type mouse brains. Fluorescence two-dimensional-difference gel electrophoresis (DIGE) and isotope-coded protein labeling (ICPL) were applied for ...

Posted in for26cat | No Comments »

Distinct processing of facial emotion of own-race versus other-race.

June 28th, 2008
Distinct processing of facial emotion of own-race versus other-race. We investigated the neural basis underlying the effect of race on incidental facial emotional processing using functional MRI. Thirteen healthy Korean men underwent functional MRI while viewing photographs of Korean (own-race) and Caucasian (other-race) emotional faces while ...

Posted in for26cat | No Comments »

Differentiation of rat adipose tissue-derived stem cells into Schwann-like cells in vitro.

June 28th, 2008
Differentiation of rat adipose tissue-derived stem cells into Schwann-like cells in vitro. In this study, we explored the competence of adipose-derived stem cells to differentiate into Schwann cells in vitro. Rat adipose-derived stem cells were sequentially treated with various factors beta-mercaptoethanol, all-trans-retinoic acid, followed by a ...

Posted in for26cat | No Comments »

In vivo gamma imaging of the secondary tumors of transplanted human fetal striatum neural stem cells

June 28th, 2008
In vivo gamma imaging of the secondary tumors of transplanted human fetal striatum neural stem cells-derived primary tumor cells. This study describes gamma-imaging of the secondary tumors from the transplanted human fetal striatum neural stem cells-derived primary tumor cells in nude mice. The subcutaneous primary tumors ...

Posted in for26cat | No Comments »

Memory trace dependence on number of stimuli in magnetic mismatch negativity.

June 28th, 2008
Memory trace dependence on number of stimuli in magnetic mismatch negativity. Mismatch negativity (MMN) reflects a comparison process between a deviant stimulus and the memory trace of standard stimuli. Although this memory mechanism has been investigated by many research studies, the development of memory representation still ...

Posted in for26cat | No Comments »

Lipopolysaccharide and hypoxia/ischemia induced IL-2 expression by microglia in neonatal brain.

June 28th, 2008
Lipopolysaccharide and hypoxia/ischemia induced IL-2 expression by microglia in neonatal brain. Using a model of perinatal brain lesions induced by lipopolysaccharide and hypoxia/ischemia, we hypothesized that interleukin-2 (IL-2), a neurotoxic cytokine, was enhanced within injured brains. We showed that lipopolysaccharide and hypoxia/ischemia enhanced both intracerebral IL-2 ...

Posted in for26cat | No Comments »

Falls Associated With Electroconvulsive Therapy Among the Geriatric Population: A Case Report.

June 28th, 2008
Falls Associated With Electroconvulsive Therapy Among the Geriatric Population: A Case Report. Electroconvulsive therapy (ECT) is the treatment of choice in many older individuals with depression and a few other conditions. Like all medical treatments, this intervention has certain possible risks, which include undesirable reactions associated ...

Posted in for26cat | No Comments »

Bitemporal Electroconvulsive Therapy for Depression in a Parkinson Disease Patient With a Deep-Brain

June 28th, 2008
Bitemporal Electroconvulsive Therapy for Depression in a Parkinson Disease Patient With a Deep-Brain Stimulator. We report the successful treatment of an episode of major depression with psychotic features with electroconvulsive therapy (ECT) in a 78-year-old woman with advanced Parkinson disease who had a left subthalamic nucleus ...

Posted in for26cat | No Comments »

Malignant catatonia: role of right unilateral electroconvulsive therapy.

June 28th, 2008
Malignant catatonia: role of right unilateral electroconvulsive therapy. Malignant catatonia is defined as a life-threatening febrile neuropsychiatric disorder, characterized by psychosis with autonomic instability, hyperactivity, mutism, and stuperous exhaustion. Although historically nearly always fatal, there has been a recent decline in mortality, secondary to earlier diagnoses ...

Posted in for26cat | No Comments »

Postictal Catatonia in a Schizophrenic Patient and Electroconvulsive Treatment.

June 28th, 2008
Postictal Catatonia in a Schizophrenic Patient and Electroconvulsive Treatment. Catatonic state has been related to variable medical, neurological, and psychiatric disorders. Although it is commonly associated with schizophrenia, epilepsy presenting as catatonialike seizures or ictal catatonia was rarely reported. Moreover, the coexistence of schizophrenia and epilepsy ...

Posted in for26cat | No Comments »

Electroconvulsive therapy, brain-derived neurotrophic factor, and possible neurorestorative benefit

June 28th, 2008
Electroconvulsive therapy, brain-derived neurotrophic factor, and possible neurorestorative benefit of the clinical application of electroconvulsive therapy. Treatment-resistant depression (TRD) is a growing problem in psychiatry. A recent meta-analysis has estimated TRD to be as high as 40%. Just over a decade ago, TRD was estimated to ...

Posted in for26cat | No Comments »

Repetitive Transcranial Magnetic Stimulation in the Treatment of Depression in Adolescents: An Open-

June 28th, 2008
Repetitive Transcranial Magnetic Stimulation in the Treatment of Depression in Adolescents: An Open-Label Study. OBJECTIVE:: This open-label pilot study examined repetitive transcranial magnetic stimulation as a possible treatment of adolescent resistant depression. METHOD:: Nine adolescents (aged 16-18 years) with severe resistant depression (determined by SCID) were ...

Posted in for26cat | No Comments »

Use of the Neuro-Wrap System for Severe Post-Electroconvulsive Therapy Headaches.

June 28th, 2008
Use of the Neuro-Wrap System for Severe Post-Electroconvulsive Therapy Headaches. OBJECTIVE:: To determine, in a nonblinded trial, if the Neuro-Wrap system is effective in reducing the severity of pain in patients with severe post-electroconvulsive therapy (ECT) headaches not adequately responsive to routine analgesic treatment. BACKGROUND:: A ...

Posted in for26cat | No Comments »

A Dissociation Between Anterograde and Retrograde Amnesia After Treatment With Electroconvulsive The

June 28th, 2008
A Dissociation Between Anterograde and Retrograde Amnesia After Treatment With Electroconvulsive Therapy: A Naturalistic Investigation. OBJECTIVE:: The aim of the present study is to investigate the cumulative effects of a clinically determined course of electroconvulsive therapy (ECT) on anterograde and retrograde amnesia. In this study, mood ...

Posted in for26cat | No Comments »

The Effectiveness of Electroconvulsive Therapy in Treatment-Resistant Depression: A Naturalistic Stu

June 28th, 2008
The Effectiveness of Electroconvulsive Therapy in Treatment-Resistant Depression: A Naturalistic Study. OBJECTIVES:: Electroconvulsive therapy (ECT) is a very effective treatment of major depressive disorder. However, its use has been declining over the years in the United Kingdom, where it is now reserved for cases where all ...

Posted in for26cat | No Comments »

The Practice of Electroconvulsive Therapy in Malawi.

June 28th, 2008
The Practice of Electroconvulsive Therapy in Malawi. OBJECTIVES:: To describe the practice of electroconvulsive therapy (ECT), including indications, efficacy, and side effects, in patients treated with unmodified ECT at Zomba Mental Hospital (ZMH) in Malawi. METHODS:: A naturalistic, descriptive cohort study that includes all patients receiving ...

Posted in for26cat | No Comments »

Orthostatic Hemodynamic Changes After Electroconvulsive Therapy Treatments.

June 28th, 2008
Orthostatic Hemodynamic Changes After Electroconvulsive Therapy Treatments. Falls are common in patients receiving electroconvulsive therapy (ECT) treatments. One cause of falls is orthostatic hypotension. In an effort to deduce whether modifiable anesthetic factors are associated with posttreatment hemodynamic changes, we assessed supine and standing blood pressure ...

Posted in for26cat | No Comments »