Medical and Biomedical Researches

Acute generalised exanthematous pustulosis and toxic epidermal necrolysis induced by carbamazepine.

June 28th, 2008
Acute generalised exanthematous pustulosis and toxic epidermal necrolysis induced by carbamazepine. Acute generalised exanthematous pustulosis and Stevens-Johnson syndrome (toxic epidermal necrolysis spectrum of severe cutaneous drug reactions) are believed to have distinct underlying pathophysiologies. Our patient, a 28-year-old Chinese woman, represents the first known reported case ...

Posted in for26cat | No Comments »

Knee locking secondary to osteochondral fracture of the patella: an unusual presentation.

June 28th, 2008
Knee locking secondary to osteochondral fracture of the patella: an unusual presentation. Acute locking is a sign of internal derangement of the knee and is an orthopaedic surgical emergency. Differential diagnoses of this condition are torn meniscus, intra-articular loose bodies and torn anterior cruciate ligament. We ...

Posted in for26cat | No Comments »

Management of heterotopic ossification affecting both hips and knees.

June 28th, 2008
Management of heterotopic ossification affecting both hips and knees. The management of heterotopic ossification is controversial. This is a rare case affecting both hips and knees of a 22-year-old woman that prevented her from walking. The management and the outcome, three years after excision of the ...

Posted in for26cat | No Comments »

Occupational exposure to body fluids among healthcare workers: a report from Iran.

June 28th, 2008
Occupational exposure to body fluids among healthcare workers: a report from Iran. INTRODUCTION: Healthcare workers (HCWs) are at substantial risk of acquiring blood-borne infections through contact with body fluids of patients. The main objectives of this study were to determine the epidemiological characteristics and risk factors ...

Posted in for26cat | No Comments »

CT findings of tuberculous peritonitis.

June 28th, 2008
CT findings of tuberculous peritonitis. INTRODUCTION: The diagnosis of tuberculous peritonitis is still challenging and very important. Early and accurate diagnosis leads to an effective therapy and good survival rates. With the widespread use of computed tomography (CT) in the abdomen, it is important to be ...

Posted in for26cat | No Comments »

Anaphylaxis during general anaesthesia: one-year survey from a British allergy clinic.

June 28th, 2008
Anaphylaxis during general anaesthesia: one-year survey from a British allergy clinic. INTRODUCTION: Anaphylaxis during general anaesthesia is a major concern. Early recognition and management of anaphylaxis, as well as its future prevention, remain a challenge for the anaesthetists, while for the allergists, the elucidation of the ...

Posted in for26cat | No Comments »

Early predictors of haemorrhage in acute febrile syndrome patients from Bucaramanga, Colombia: a den

June 28th, 2008
Early predictors of haemorrhage in acute febrile syndrome patients from Bucaramanga, Colombia: a dengue endemic area. INTRODUCTION: Spontaneous haemorrhage is an important cause of hospitalisation in dengue patients. Early predictors of these complications could help to make opportune decisions. METHODS: We prospectively evaluated 51 febrile patients ...

Posted in for26cat | No Comments »

Do young adults with uncomplicated dengue fever need hospitalisation? A retrospective analysis of cl

June 28th, 2008
Do young adults with uncomplicated dengue fever need hospitalisation? A retrospective analysis of clinical and laboratory features. INTRODUCTION: Approximately 80 percent of all notified cases of dengue infections in Singapore were hospitalised from 2000 to 2005. We aimed to determine if hospitalised dengue patients had significant ...

Posted in for26cat | No Comments »

Fast-track method in cardiac surgery: evaluation of risks and benefits of continuous administration

June 28th, 2008
Fast-track method in cardiac surgery: evaluation of risks and benefits of continuous administration technique. INTRODUCTION: Fast-track is a method proposed to decrease medical costs through the reduction of patients\' length of stay in the hospital. This study was carried out to assess the risks and benefits ...

Posted in for26cat | No Comments »

Comparison of nested-polymerase chain reaction and virus culture for the diagnosis of genital herpes

June 28th, 2008
Comparison of nested-polymerase chain reaction and virus culture for the diagnosis of genital herpes simplex virus infection. INTRODUCTION: This study was performed to compare nested-polymerase chain reaction (PCR) with viral culture as a diagnostic tool for genital herpes simplex virus (HSV) infection in a sexually transmitted ...

Posted in for26cat | No Comments »

Comparison between use of neuromuscular blocking agent and placebo with the intubating laryngeal mas

June 28th, 2008
Comparison between use of neuromuscular blocking agent and placebo with the intubating laryngeal mask airway. INTRODUCTION: The intubating laryngeal mask airway (ILMA) is a specially-designed airway device that can be used for endotracheal intubation without direct laryngoscopy. The advantage of this device is that it allows ...

Posted in for26cat | No Comments »

Severe community-acquired pneumonia requiring intensive care: a study of 80 cases from Singapore.

June 28th, 2008
Severe community-acquired pneumonia requiring intensive care: a study of 80 cases from Singapore. INTRODUCTION: Severe community-acquired pneumonia is a major cause of mortality and morbidity worldwide. This study looked at the clinical characteristics of these patients admitted to a Singaporean community hospital and the prognostic impact ...

Posted in for26cat | No Comments »

Evaluation of a urinary metanephrines reagent kit: an automated approach.

June 28th, 2008
Evaluation of a urinary metanephrines reagent kit: an automated approach. INTRODUCTION: We report the results of a laboratory evaluation of the BioRad Urinary Metanephrines Reagent Kit. The test was designed for the quantitative measurement of normetanephrine and metanephrine in urine by high performance liquid chromatography. The ...

Posted in for26cat | No Comments »

Diagnostic laparoscopy in the evaluation of right lower abdominal pain: a one-year audit.

June 28th, 2008
Diagnostic laparoscopy in the evaluation of right lower abdominal pain: a one-year audit. INTRODUCTION: Acute appendicitis is the commonest cause for right lower abdominal pain. Clinical features, laboratory and imaging investigations are either not very sensitive or specific, and neither is therapeutic. We aimed to define ...

Posted in for26cat | No Comments »

Bruises, blood coagulation tests and the battered child syndrome.

June 28th, 2008
Bruises, blood coagulation tests and the battered child syndrome. Cutaneous bruises are a common symptom and a sign of injury and blood coagulation disorders in childhood. A carefully-taken history, coupled with a thorough physical examination, would lead to the diagnosis, or guide the clinician to the ...

Posted in for26cat | No Comments »

Employing mirtazapine to aid benzodiazepine withdrawal.

June 28th, 2008
Employing mirtazapine to aid benzodiazepine withdrawal. Insomnia and depression are frequently encountered in patients during withdrawal from substances. While there are no approved medications for treating them, off-label attempts to address these phenomena with mirtazapine have shown some promising results. This case describes the use of ...

Posted in for26cat | No Comments »

C-reactive protein as an indicator of aqueductal gliosis and hydrocephaly in neonatal meningitis.

June 28th, 2008
C-reactive protein as an indicator of aqueductal gliosis and hydrocephaly in neonatal meningitis. Serial C-reactive protein (CRP) measurements appear to be helpful in following clinical course and response to treatment of serious bacterial infections in neonates, such as meningitis, septicaemia and osteomyelitis. In previous studies, serial ...

Posted in for26cat | No Comments »

Phrynoderma: a forgotten entity in a developed country.

June 28th, 2008
Phrynoderma: a forgotten entity in a developed country. Phrynoderma is a type of follicular hyperkeratosis attributed to various nutritional deficiencies, most notably vitamin A. We report a case of a 31-year-old mentally-deficient man who was a resident of a voluntary welfare nursing home. He presented with ...

Posted in for26cat | No Comments »

Conservative management of placenta accreta: review of three cases.

June 28th, 2008
Conservative management of placenta accreta: review of three cases. Placenta accreta occurs when the placenta is abnormally adherent to the uterus, often resulting in complications in the peripartum period such as severe haemorrhage, a possible need for caesarean hysterectomy, and even severe injuries to pelvic organs. ...

Posted in for26cat | No Comments »

Multiple variations of the right renal vessels.

June 28th, 2008
Multiple variations of the right renal vessels. Multiple variations of the right renal and testicular vessels were found during routine dissection in a 65-year-old male cadaver. The cadaver was healthy and did not have any other anomalies. The variations found were: presence of three right renal ...

Posted in for26cat | No Comments »

Ruptured superficial femoral artery aneurysm treated by simple ligation.

June 28th, 2008
Ruptured superficial femoral artery aneurysm treated by simple ligation. A 79-year-old man, with a background of peripheral vascular disease, presented to the emergency department with a sudden increase in the size of his swelling in the right thigh, indicating rupture of his right superficial femoral artery ...

Posted in for26cat | No Comments »

Unusual cause of seizures in Singapore: neurocysticercosis.

June 28th, 2008
Unusual cause of seizures in Singapore: neurocysticercosis. Neurocysticercosis is the commonest cause for adult onset of seizures in developing countries, and is relatively uncommon in Singapore. However, with the influx of foreign workers from developing countries, we need to consider it as a differential diagnosis in ...

Posted in for26cat | No Comments »

An eight-year-old girl with probable Lyme disease in Hong Kong.

June 28th, 2008
An eight-year-old girl with probable Lyme disease in Hong Kong. An eight-year-old girl presented with acute cerebellar syndrome and meningitis. Lumbar puncture showed elevated pressure. Examination of the cerebrospinal fluid showed lymphocytosis, raised protein and decreased glucose. She was initially treated with acyclovir and antituberculosis drugs ...

Posted in for26cat | No Comments »

[Laveran, Marchiafava and the paludism.]

June 28th, 2008
[Laveran, Marchiafava and the paludism.] The discovery in 1880 of the malaria parasite by the French investigator Alphonse Laveran found for almost ten years the obstinate refusal from the italian Ettore Marchiafava, who saw in the parasitic elements only degenerative forms of the erythrocytes. The acknowledgement ...

Posted in for26cat | No Comments »

[Trichosporon asahii fatal infection in a preterm newborn.]

June 28th, 2008
[Trichosporon asahii fatal infection in a preterm newborn.] We present a case of Trichosporon asahii fatal infection recognized post mortem in a premature newborn baby of 685 g. Trichosporon asahii isolated from endovascular catheters and endotraqueal tube, is an opportunistic yeast described like an emergent pathogen ...

Posted in for26cat | No Comments »