Archive for May, 2008
Thursday, May 1st, 2008
Technical Performance of Colonoscopy: The Key Role of Sedation/Analgesia and Other Quality Indicators.
BACKGROUND: It is essential to identify the factors in clinical practice that influence the technical performance of colonoscopy as a basis for quality improvement programs. AIMS: To assess the factors linked to two ...
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Thursday, May 1st, 2008
Characteristics of Symptomatic Reflux Episodes on Acid Suppressive Therapy.
BACKGROUND: Persistent symptoms on acid suppressive therapy are due to either acid or nonacid gastroesophageal reflux (GER) episodes or are not related to reflux. AIM: To compare physical and chemical characteristics of GER episodes associated with symptoms ...
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Thursday, May 1st, 2008
THE MORAL IMPORTANCE OF SELECTING PEOPLE RANDOMLY.
This article discusses some ethical principles for distributing pandemic influenza vaccine and other indivisible goods. I argue that a number of principles for distributing pandemic influenza vaccine recently adopted by several national governments are morally unacceptable because they put ...
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Thursday, May 1st, 2008
PROCREATIVE REASONS-RELEVANCE: ON THE MORAL SIGNIFICANCE OF WHY WE HAVE CHILDREN.
Advances in reproductive technologies - in particular in genetic screening and selection - have occasioned renewed interest in the moral justifiability of the reasons that motivate the decision to have a child. The capacity to ...
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Thursday, May 1st, 2008
WHY WE ARE NOT MORALLY REQUIRED TO SELECT THE BEST CHILDREN: A RESPONSE TO SAVULESCU.
The purpose of this paper is to review critically Julian Savulescu\'s principle of \'Procreative Beneficence,\' which holds that prospective parents are morally obligated to select, of the possible children they could ...
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Thursday, May 1st, 2008
FREE RIDERS AND PIOUS SONS - WHY SCIENCE RESEARCH REMAINS OBLIGATORY.
John Harris has previously proposed that there is a moral duty to participate in scientific research. This concept has recently been challenged by Iain Brassington, who asserts that the principles cited by Harris in support ...
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Thursday, May 1st, 2008
MEDICAL CONFIDENTIALITY: LEGAL AND ETHICAL ASPECTS IN GREECE.
Respect for confidentiality is firmly established in codes of ethics and law. Medical care and the patients\' trust depend on the ability of the doctors to maintain confidentiality. Without a guarantee of confidentiality, many patients would want to ...
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Thursday, May 1st, 2008
ENHANCEMENTS, EASY SHORTCUTS, AND THE RICHNESS OF HUMAN ACTIVITIES.
One argument that is frequently invoked against the technological enhancement of human functioning is that it is morally suspect, or even wrong, to take an easy shortcut. Some things that usually take effort, endurance or struggle can ...
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Thursday, May 1st, 2008
MEK inhibition induces caspases activation, differentiation blockade and PML/RARalpha degradation in acute promyelocytic leukaemia.
The hallmark of acute promyelocytic leukaemia (APL) is the reciprocal translocation t(15;17), which leads to the expression of the promyelocytic leukaemia/retinoic acid receptor alpha (PML/RARalpha) fusion protein and a cell differentiation blockade ...
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Thursday, May 1st, 2008
Cluster immunotherapy with a glutaraldehyde-modified mixture of grasses results in an improvement in specific nasal provocation tests in less than 2.5 months of treatment.
Background Cluster immunotherapy is becoming increasingly used. It allows for a rapid build up phase and the administration of higher doses of ...
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Thursday, May 1st, 2008
Clinical and epidemiological features of patients with genitourinary tract tumour in a blackfoot disease endemic area of Taiwan.
OBJECTIVES To evaluate the clinical and epidemiological characteristics of patients with genitourinary (GU) tract transitional cell carcinoma (TCC) in an endemic area of blackfoot disease (BFD), the arsenic-exposed ...
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Thursday, May 1st, 2008
Correlation of the International Prostate Symptom Score bother question with the Benign Prostatic Hyperplasia Impact Index in a clinical practice setting.
OBJECTIVE To evaluate the association between the International Prostate Symptom Score (IPSS) bother question (BQ) and a validated disease-specific quality-of-life questionnaire, the Benign Prostatic Hyperplasia ...
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Thursday, May 1st, 2008
Altered Adhesive Structures and Their Relation to RhoGTPase Activation in Merlin-Deficient Schwannoma.
Schwannomas are Schwann cell tumors of the nervous system that occur spontaneously and in patients with neurofibromatosis 2 (NF2) and lack the tumor suppressor merlin. Merlin is known to bind paxillin, beta1 integrin and ...
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Thursday, May 1st, 2008
Effects of Artificial Roosts for Frugivorous Bats on Seed Dispersal in a Neotropical Forest Pasture Mosaic.
In the Neotropics ongoing deforestation is producing open and heavily fragmented landscapes dominated by agriculture, mostly plantations and cattle pastures. After some time agriculture often becomes uneconomical and land is ...
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Thursday, May 1st, 2008
Current Trends in Plant and Animal Population Monitoring.
Animal and plant population monitoring programs are critical for identifying species at risk, evaluating the effects of management or harvest, and tracking invasive and pest species. Nevertheless, monitoring activities are highly decentralized, which makes it difficult for researchers ...
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Thursday, May 1st, 2008
Influence of Representation Targets on the Total Area of Conservation-Area Networks.
Systematic conservation planning typically requires specification of quantitative representation targets for biodiversity surrogates such as species, vegetation types, and environmental parameters. Targets are usually specified either as the minimum total area in a conservation-area network ...
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Thursday, May 1st, 2008
Household Location Choices: Implications for Biodiversity Conservation.
Successful conservation efforts require understanding human behaviors that directly affect biodiversity. Choice of household location represents an observable behavior that has direct effects on biodiversity conservation, but no one has examined the sociocultural predictors of this choice relative to ...
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Thursday, May 1st, 2008
THE INTERNATIONAL DIMENSIONS OF NEUROETHICS.
Neuroethics, in its modern form, investigates the impact of brain science in four basic dimensions: the self, social policy, practice and discourse. In this study, we analyzed a set of 461 peer-reviewed articles with neuroethics content, published by authors from 32 ...
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Thursday, May 1st, 2008
REPORTING OF INFORMED CONSENT, STANDARD OF CARE AND POST-TRIAL OBLIGATIONS IN GLOBAL RANDOMIZED INTERVENTION TRIALS: A SYSTEMATIC SURVEY OF REGISTERED TRIALS.
Objective: Ethical guidelines are designed to ensure benefits, protection and respect of participants in clinical research. Clinical trials must now be registered on open-access databases ...
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Thursday, May 1st, 2008
Arterial stiffness, endothelial function and microcirculatory reactivity in healthy young males.
Large (C1) and small (C2) arterial stiffness has been suggested to parallel endothelial reactivity and has led researchers to suggest parameters of arterial stiffness may be alternative measures to brachial sonographic assessments of flow-mediated dilatation ...
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Thursday, May 1st, 2008
Keratoacanthoma with perineural invasion: An indicator for aggressive behavior?
Neurotropic invasion of keratoacanthoma (KA) is rare and can easily be missed histologically. A 36-year-old woman developed a KA on the upper lip four weeks after CO(2) laser skin resurfacing; it showed microscopic evidence of perineural invasion. ...
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Thursday, May 1st, 2008
Antipruritic effect of cyclosporine microemulsion in prurigo nodularis: Results of a case series.
Background: Prurigo nodularis shows intense itching nodules, which are often persistent and therapy refractory. Histological alterations include fibrosis of collagen fibers and presence of inflammatory infiltrate, which partly explains the clinical persistence of ...
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Thursday, May 1st, 2008
Retrovirus vector-mediated gene transfer into the chick optic vesicle by in ovo electroporation.
Owing to its external position in the embryo, the chick eye has been used as a readily accessible model for studying the molecular mechanisms behind the patterning of the central nervous system. Although ...
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Thursday, May 1st, 2008
Novel two-step Ca(2+) increase and its mechanisms and functions at fertilization in oocytes of the annelidan worm Pseudopotamilla occelata.
Mature oocytes of the annelidan worm Pseudopotamilla occelata have a wide perivitelline space between the oocyte surface and the vitelline envelope and are arrested at the first ...
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Thursday, May 1st, 2008
Transgenic zebrafish expressing fluorescent proteins in central nervous system neurons.
Zebrafish is a powerful model system for investigations of vertebrate neural development. The animal has also become an important model for studies of neuronal function. Both in developmental and functional studies, transgenic zebrafish expressing fluorescent proteins ...
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