Archive for the ‘researches 3’ Category
Sunday, March 16th, 2008
First description of polycystic kidney disease in a Portuguese journal.
de Almeida EA, Prata MM.
Serviço de Nefrologia e Transplantação Renal, Hospital de Santa Maria, Lisboa, Portugal.
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Sunday, March 16th, 2008
Comparing the automated versus manual method of needle biopsy for renal histology artefacts.
Donnelly S, Goodyer P, Mauer M; for the RASS Investigators.
1Department of Medicine, University of Toronto, Toronto, Ontario.
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Sunday, March 16th, 2008
HLA-DQ3 is a probable risk factor for CMV infection in high-risk kidney transplant patients.
BACKGROUND: Cytomegalovirus (CMV) infection in transplant patients with special risk factors remains a major hazard. CMV-seronegative recipients with seropositive donors have the highest risk of developing acute CMV disease. We suggest that ...
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Sunday, March 16th, 2008
\"And they told two friends...and so on\": RJ Reynolds\' Viral Marketing of Eclipse and Its Potential to Mislead the Public.
OBJECTIVE: To explore RJ Reynolds\' viral marketing strategies for Eclipse cigarettes. METHODS: Analysis of previously secret tobacco industry documents and multimedia materials. RESULTS: The failure of ...
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Sunday, March 16th, 2008
Nephron number determines susceptibility to renal mass reduction-induced CKD in Lewis and Fisher 344 rats: implications for development of experimentally induced chronic allograft nephropathy.
BACKGROUND: The Fisher 344 (F344) rat kidney transplanted to a Lewis rat recipient is a common model of chronic renal allograft nephropathy ...
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Sunday, March 16th, 2008
The Birmingham Rehabilitation Uptake Maximisation study (BRUM): a randomised controlled trial comparing home-based with centre-based cardiac rehabilitation.
Objective To compare the outcomes of home-based (using the Heart Manual) and centre-based cardiac rehabilitation programmes. Design Randomised controlled trial & parallel economic evaluation. Setting Predominantly inner-city, multi-ethnic population ...
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Sunday, March 16th, 2008
Short- and Long-Term Outcomes Following Atrial Fibrillation in Patients With Acute Coronary Syndromes With or Without ST-Segment Elevation.
Objective Assess variables associated with the occurrence of atrial fibrillation (AF) and the relation of AF with short- and long-term outcomes and with other in-hospital complications in patients ...
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Sunday, March 16th, 2008
How to Cost Cardiovascular Care.
Introduction Health economics is gaining increasing importance in cardiovascular disease management. This is not surprising given increasing numbers of therapies, devices and diagnostic tools available each year in an everlasting quest to prevent the further occurrence of cardiovascular events. The question ...
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Sunday, March 16th, 2008
Stenting of the right ventricular outflow tract in the symptomatic infant with tetralogy of Fallot.
Background Repair of neonatal TOF has low mortality. Debate continues regarding the initial management of cyanotic or duct-dependent infants with TOF and adverse risk factors. Whilst repair can and has been ...
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Sunday, March 16th, 2008
The Association Of Arterial Access Site At Angioplasty With Transfusion And Mortality The M.O.R.T.A.L Study: (Mortality benefit of Reduced Transfusion After PCI via the Arm or Leg).
Context Bleeding and transfusion following percutaneous coronary intervention are known predictors of mortality. Trans-radial arterial access reduces bleeding and ...
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Sunday, March 16th, 2008
Trypsin, elastase, plasmin and MMP-9 activity in the serum during the human ageing process.
OBJECTIVE: the aim of this work was to define the influence of the ageing process on the activity of proteolytic enzymes, such as trypsin, elastase, plasmin and active MMP-9 concentration, as well ...
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Sunday, March 16th, 2008
The Mental Capacity Act: some implications for black and minority ethnic elders.
Shah A, Heginbotham C.
West London Mental Health NHS Trust, Uxbridge Road, Southall, Middlesex, UB1 3EU, United Kingdom, UK.
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Sunday, March 16th, 2008
Insulin sensitivity and beta-cell function in older Japanese adults without diabetes.
Kanauchi M, Kanauchi K, Inoue T, Kimura K, Saito Y.
Nara Medical University, First Department of Internal Medicine, 840, Shijo-cho Kashihara Nara 634-0813, Japan.
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Sunday, March 16th, 2008
Evaluating the impact of the National Service Framework for Older People; qualitative science or populist propaganda?
Powell SL.
Specialist Registrar in Geriatric Medicine, Royal Oldham Hospital, Rochdale Road, Oldham, UK.
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Sunday, March 16th, 2008
Incidence, preventability and consequences of adverse events in older people: results of a retrospective case-note review.
OBJECTIVES: to estimate the extent, preventability and consequences of adverse clinical events in elderly and non-elderly patients. DESIGN: a two-stage structured, retrospective, patient case-note review. SETTING: a large NHS hospital ...
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Sunday, March 16th, 2008
Addenbrooke\'s Cognitive Examination - Revised in day-to-day clinical practice.
Woodford HJ, George J.
Department of Elderly Medicine, Cumberland Infirmary, Carlisle, CA2 7HY, UK.
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Sunday, March 16th, 2008
Cluster randomised trial of a targeted multifactorial intervention to prevent falls among older people in hospital.
OBJECTIVE: To determine the efficacy of a targeted multifactorial falls prevention programme in elderly care wards with relatively short lengths of stay. DESIGN: Cluster randomised trial. SETTING: 24 elderly care ...
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Sunday, March 16th, 2008
Effectiveness of single dose rifampicin in preventing leprosy in close contacts of patients with newly diagnosed leprosy: cluster randomised controlled trial.
OBJECTIVE: To determine the effectiveness of chemoprophylaxis using a single dose of rifampicin to prevent leprosy in close contacts. DESIGN: Single centre, double blind, cluster ...
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Sunday, March 16th, 2008
ABPI/BIOSCIENCE FEDERATION \'In vivo sciences in the UK: Sustaining the supply of skills in the 21st century\': Fast-tracking a U-turn.
Stanford SC.
University College London, Gower Street, London WC1E 6BT, UK, . c.stanford@ucl.ac.uk.
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Sunday, March 16th, 2008
OCD and anxiety: from afterthought to independence.
Craig KJ, Fineberg NA.
Behavioural and Clinical Neuroscience Institute (BCNI), University of Cambridge, Cambridge, UK. kjc36@cam.ac.uk.
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Sunday, March 16th, 2008
Excision Repair is Required for Genotoxin-Induced Mutagenesis in Mammalian Cells.
Certain hexavalent chromium [Cr(VI)] compounds are human lung carcinogens. Although much is known about Cr-induced DNA damage, very little is known about mechanisms of Cr(VI) mutagenesis and the role that DNA repair plays in this process. ...
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Sunday, March 16th, 2008
A distinct ERCC1 haplotype is associated with mRNA expression levels in prostate cancer patients.
Both genetic variants and mRNA expression of DNA repair and tumor suppressor genes have been investigated as molecular markers for therapy outcome. However, the phenotypic impact of genetic variants often remained unclear, ...
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Sunday, March 16th, 2008
Genomic Analysis Suggests Higher Susceptibility Of Children To Air Pollution.
Differences in biological responses to exposure to hazardous airborne substances between children and adults have been reported, suggesting children to be more susceptible. Aim of this study was to improve our understanding of differences in susceptibility ...
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Sunday, March 16th, 2008
Phthalate Induction of CYP3A4 is Dependent on Glucocorticoid Regulation of PXR Expression.
Cytochrome P450 3A4 (CYP3A4) is responsible for oxidative metabolism of more than 60% of all pharmaceuticals. CYP3A4 is inducible by xenobiotics that activate pregnane X receptor (PXR), and enhanced 3A4 activity has been implicated ...
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Sunday, March 16th, 2008
Heme-oxygenase 1 gene expression is a marker for hexavalent chromium-induced stress and toxicity in human dermal fibroblasts.
Several adverse health effects, including irritant and allergic contact dermatitis, have been reported among workers who are occupationally exposed to chromium-containing compounds. Human dermal fibroblasts were used as an ...
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