Archive for the ‘researches 3’ Category

A Novel Variant of Combined Granular-Lattice Corneal Dystrophy Associated With the Met619Lys Mutatio

Sunday, March 16th, 2008

A Novel Variant of Combined Granular-Lattice Corneal Dystrophy Associated With the Met619Lys Mutation in the TGFBI Gene. OBJECTIVE: To report a novel mutation in TGFBI (GenBank NM_000358), p.Met619Lys, associated with a variant of combined granular-lattice corneal dystrophy. METHODS: Slitlamp examination and DNA collection from the proband ...

Associations Between Age-Related Nuclear Cataract and Lutein and Zeaxanthin in the Diet and Serum in

Sunday, March 16th, 2008

Associations Between Age-Related Nuclear Cataract and Lutein and Zeaxanthin in the Diet and Serum in the Carotenoids in the Age-Related Eye Disease Study (CAREDS), an Ancillary Study of the Women\'s Health Initiative. OBJECTIVE: To evaluate associations between nuclear cataract (determined from slitlamp photographs between May 2001 ...

Open-angle Glaucoma and Mortality: The Barbados Eye Studies.

Sunday, March 16th, 2008

Open-angle Glaucoma and Mortality: The Barbados Eye Studies. OBJECTIVE: To evaluate the relationship between open-angle glaucoma (OAG) and mortality in a black population at 9-years\' follow-up. DESIGN: Population-based cohort study of 4092 black participants (aged 40-84 years at baseline) in the Barbados Eye Studies. Open-angle glaucoma ...

Eye water.

Sunday, March 16th, 2008

Eye water.

Effect of human tears on acanthamoeba-induced cytopathic effect.

Sunday, March 16th, 2008

Effect of human tears on acanthamoeba-induced cytopathic effect. OBJECTIVE: To determine whether tears of healthy individuals provide protection against Acanthamoeba-induced cytopathic effect (CPE) in vitro. METHODS: Acanthamoebae were added to confluent cultures of corneal epithelium in 24-well plates, and co-cultures were incubated overnight in a serum-free ...

Age at onset curves of retinitis pigmentosa.

Sunday, March 16th, 2008

Age at onset curves of retinitis pigmentosa. OBJECTIVE: To calculate age at onset curves of retinitis pigmentosa (RP) to resolve the difficulty in calculating the recurrence risk in a family. Retinitis pigmentosa is a common hereditary retinal disease that leads to blindness. It is a slow-onset ...

Penetration of voriconazole, 1%, eyedrops into human aqueous humor: a prospective open-label study.

Sunday, March 16th, 2008

Penetration of voriconazole, 1%, eyedrops into human aqueous humor: a prospective open-label study. OBJECTIVE: To determine the therapeutic efficacy of adjuvant use of voriconazole, 1%, eyedrops in the treatment of refractory fungal keratitis. METHODS: A prospective open-label trial was conducted to determine voriconazole levels obtained in ...

Correlation of Functional Impairment and Morphological Alterations in Patients With Group 2A Idiopat

Sunday, March 16th, 2008

Correlation of Functional Impairment and Morphological Alterations in Patients With Group 2A Idiopathic Juxtafoveal Retinal Telangiectasia. OBJECTIVE: To correlate functional impairment with morphological alterations in patients with group 2A idiopathic juxtafoveal retinal telangiectasia. METHODS: As part of the Macular Telangiectasia Project, a cohort of 10 patients ...

Macular Dystrophy Associated With the A3243G Mitochondrial DNA Mutation: Distinct Retinal and Associ

Sunday, March 16th, 2008

Macular Dystrophy Associated With the A3243G Mitochondrial DNA Mutation: Distinct Retinal and Associated Features, Disease Variability, and Characterization of Asymptomatic Family Members. OBJECTIVES: To determine (1) detailed retinal and audiological features of probands harboring the A3243G mitochondrial DNA mutation (m.3243A>G) and their asymptomatic maternal relatives, (2) ...

Acupuncture ineffective, attention effective?

Sunday, March 16th, 2008

Acupuncture ineffective, attention effective? Ernst E. Department of Complementary Medicine, Universities of Exeter & Plymouth, 25 Victoria Park Rd, Exeter EX2 4NT, England. Edzard.Ernst@pms.ac.uk.

Intraocular Pressure-Lowering Effects and Safety of Topical Administration of a Selective ROCK Inhib

Sunday, March 16th, 2008

Intraocular Pressure-Lowering Effects and Safety of Topical Administration of a Selective ROCK Inhibitor, SNJ-1656, in Healthy Volunteers. OBJECTIVE: To investigate the effects and safety of topical administration of an ophthalmic solution of a selective Rho-associated coiled coil-forming protein kinase (ROCK) inhibitor, SNJ-1656, 0.003% to 0.1%, in ...

Is aspirin resistance due to noncompliance?

Sunday, March 16th, 2008

Is aspirin resistance due to noncompliance? Dalen JE. Department of Medicine, University of Arizona, 1840 E River Rd, Ste 120, Tucson, AZ 87518. jamesdalen@yahoo.com.

Laboratory-Defined Aspirin Resistance and Recurrent Cardiovascular Events.

Sunday, March 16th, 2008

Laboratory-Defined Aspirin Resistance and Recurrent Cardiovascular Events. Fontana P, Reny JL. Department of Internal Medicine, Centre Hospitalier de Béziers 2 rue Valentin Hauÿ, F-34525 Béziers CEDEX, France. jean-luc.reny@ch-beziers.fr), and Dr Fontana, Division of Angiology and Haemostasis, Department of Internal Medicine, Faculty of Medicine and ...

Acupuncture trial lacks a priori rationale to refute null hypothesis.

Sunday, March 16th, 2008

Acupuncture trial lacks a priori rationale to refute null hypothesis. Moffet HH. Division of Research, Kaiser Permanente, 2000 Broadway, Oakland, CA 94611. howard.h.moffet@kp.org.

Low-dose rosiglitazone in patients with type 2 diabetes mellitus requiring insulin therapy.

Sunday, March 16th, 2008

Low-dose rosiglitazone in patients with type 2 diabetes mellitus requiring insulin therapy. Lopez CA, Kanna B. Department of Internal Medicine, Lincoln Medical and Health Center, 234 E 149th St, Bronx, NY 10451. doctorcesarlopez@yahoo.com.

The representation of women on the editorial boards of major medical journals: a 35-year perspective

Sunday, March 16th, 2008

The representation of women on the editorial boards of major medical journals: a 35-year perspective. Jagsi R, Tarbell NJ, Henault LE, Chang Y, Hylek EM. Department of Radiation Oncology, University of Michigan Hospital, 1500 E Medical Center Dr, Room B2C490, Ann Arbor, MI 48109-5010. ...

Neither Freedom nor Autonomy Without Beneficence.

Sunday, March 16th, 2008

Neither Freedom nor Autonomy Without Beneficence. d\'Aloja E, Pintor M, Paribello F, Pisu S. Department of Forensic Medicine, Cagliari University, SS 554 bivio Sestu, Cagliari 09042, Italy. ernestodaloja@pacs.unica.it.

Dealing with delicate issues in continuous deep sedation: varying practices among dutch medical spec

Sunday, March 16th, 2008

Dealing with delicate issues in continuous deep sedation: varying practices among dutch medical specialists, general practitioners, and nursing home physicians. BACKGROUND: This article examines delicate issues in continuous deep sedation (CDS) from the perspectives of different types of physicians. The following sensitive issues involved in CDS ...

Adjuvant chemotherapy after resection in elderly medicare and medicaid patients with colon cancer.

Sunday, March 16th, 2008

Adjuvant chemotherapy after resection in elderly medicare and medicaid patients with colon cancer. BACKGROUND: This study investigated the influence of Medicaid enrollment on the receipt and completion of adjuvant chemotherapy and the likelihood of evaluation by an oncologist for those patients who do not initiate chemotherapy. ...

Randomized controlled trial of web-based alcohol screening and brief intervention in primary care.

Sunday, March 16th, 2008

Randomized controlled trial of web-based alcohol screening and brief intervention in primary care. BACKGROUND: There is compelling evidence supporting screening and brief intervention (SBI) for hazardous drinking, yet it remains underused in primary health care. Electronic (computer or Web-based) SBI (e-SBI) offers the prospects of ease ...

Screening mammography in older women: effect of wealth and prognosis.

Sunday, March 16th, 2008

Screening mammography in older women: effect of wealth and prognosis. BACKGROUND: Wealthy women have higher rates of screening mammography than poor women do. Screening mammography is beneficial for women with substantial life expectancies, but women with limited life expectancies are unlikely to benefit. It is unknown ...

The anticholinergic risk scale and anticholinergic adverse effects in older persons.

Sunday, March 16th, 2008

The anticholinergic risk scale and anticholinergic adverse effects in older persons. BACKGROUND: Adverse effects of anticholinergic medications may contribute to events such as falls, delirium, and cognitive impairment in older patients. To further assess this risk, we developed the Anticholinergic Risk Scale (ARS), a ranked categorical ...

The Accreditation Council for Graduate Medical Education’s Limits on Residents’ Work Hours and Pat

Sunday, March 16th, 2008

The Accreditation Council for Graduate Medical Education\'s Limits on Residents\' Work Hours and Patient Safety: A Study of Resident Experiences and Perceptions Before and After Hours Reductions. BACKGROUND: Limiting resident work hours may improve patient safety, but unintended adverse effects are also possible. We sought to ...

Geographic Variation and Risk of Skin Cancer in US Women: Differences Between Melanoma, Squamous Cel

Sunday, March 16th, 2008

Geographic Variation and Risk of Skin Cancer in US Women: Differences Between Melanoma, Squamous Cell Carcinoma, and Basal Cell Carcinoma. BACKGROUND: Occurrences of melanoma, squamous cell carcinoma (SCC), and basal cell carcinoma (BCC) have been associated with varying geography. Our goal was to evaluate differences in ...

Association of Early Follow-up After Acute Myocardial Infarction With Higher Rates of Medication Use

Sunday, March 16th, 2008

Association of Early Follow-up After Acute Myocardial Infarction With Higher Rates of Medication Use--Invited Commentary. Jackson EA. Division of Cardiovascular Medicine, University of Michigan Health System, 24 Frank Lloyd Wright Dr, Ann Arbor, MI 48106. lisjack@umich.edu.

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