Archive for the ‘researches 3’ Category
Saturday, March 29th, 2008
Periodic abdominal pumping supports leg development during metamorphosis in tenebrionid beetle Zophobas atratus.
Rhythmic abdominal pumping movements in a pupa of giant mealworm beetle Zophobas atratus caused large hemolymph pressure pulses of approximately 20 mmHg. The abdominal pumping movements were completely blocked by transecting the ventral ...
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Saturday, March 29th, 2008
Molecular modeling optimization of anticoagulant pyridine derivatives.
Intravascular clotting remains a major health problem in the United States, the most prominent being deep vein thrombosis, pulmonary embolism and thromboembolic stroke. Previous reports on the use of pyridine derivatives in cardiovascular drug development encourage us to pursue ...
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Saturday, March 29th, 2008
3D-QSAR and molecular docking studies of 1,3,5-triazene-2,4-diamine derivatives against r-RNA: Novel bacterial translation inhibitors.
Aminoglycoside mimetics inhibit bacterial translation by interfering with the ribosomal decoding site. To elucidate the structural properties of these compounds important for antibacterial activity, comparative molecular field analysis (CoMFA) and comparative molecular ...
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Saturday, March 29th, 2008
Role of cytokines in mediating mechanical hypernociception in a model of delayed-type hypersensitivity in mice.
In the present study, we used the electronic version of the von Frey test to investigate the role of cytokines (TNF-alpha and IL-1beta) and chemokines (KC/CXCL-1) in the genesis of mechanical ...
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Saturday, March 29th, 2008
Appetitive memory reconsolidation depends upon NMDA receptor-mediated neurotransmission.
Memory persistence is a dynamic process involving the reconsolidation of memories after their reactivation. Reconsolidation impairments have been demonstrated for many types of memories in rats, and signaling at N-methyl-d-aspartate (NMDA) receptors appears often to be a critical ...
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Saturday, March 29th, 2008
The comparison of self-administered University of California, Los Angeles shoulder score with traditional University of California, Los Angeles shoulder score completed by clinicians in assessing outcome of rotator cuff surgery.
To determine whether the University of California, Los Angeles (UCLA) shoulder score completed by the patient ...
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Saturday, March 29th, 2008
Characterization of an ADAMTS-5-mediated cleavage site in aggrecan in OSM-stimulated bovine cartilage.
OBJECTIVE: In a previous study, we identified a 50-kDa G3-containing aggrecan degradation product in bovine cartilage, released from the tissue after interleukin-1 (IL-1) stimulation in the presence of oncostatin M (OSM). Our objective was ...
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Saturday, March 29th, 2008
A novel lesion of the infraspinatus characterized by musculotendinous disruption, edema, and late fatty infiltration.
Isolated, atraumatic rupture of the infraspinatus (IS) with associated edema of its muscle is a previously undescribed lesion. We retrospectively identified 19 patients with MRI detected, isolated lesions of the IS ...
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Saturday, March 29th, 2008
Allohexaploidy, introgression, and the complex phylogenetic history of Elymus repens (Poaceae).
The phylogenetic position of hexaploid Elymus repens within the tribe Triticeae (Poaceae) was examined using cloned sequences from the low-copy nuclear genes encoding phosphoenolpyruvate carboxylase (pepC) and beta-amylase. A previous analysis of E. repens using ...
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Saturday, March 29th, 2008
Towards the phylogeny of chafers (Sericini): Analysis of alignment-variable sequences and the evolution of segment numbers in the antennal club.
Scarabaeoid beetles display a distinctive lamellate antenna carrying olfactory sensillae which show various trends of surface enlargement, including the increased number of the terminal lamellate antennomeres. ...
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Saturday, March 29th, 2008
The rapid accumulation of consistent molecular support for intergeneric crocodylian relationships.
Gatesy J, Amato G.
Department of Biology, University of California, Spieth Hall, Riverside, CA 92521, USA.
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Saturday, March 29th, 2008
Prospective isolation of functionally distinct radial glial subtypes-Lineage and transcriptome analysis.
Since the discovery of radial glia as the source of neurons, their heterogeneity in regard to neurogenesis has been described by clonal and time-lapse analysis in vitro. However, the molecular determinants specifying neurogenic radial glia ...
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Saturday, March 29th, 2008
Activity standardization of (22)Na.
The activity of a (22)Na solution was measured by means of two 4pibeta-gamma coincidence-counting techniques. The first method corresponds to the classical 4pibeta-gamma coincidence counting and requires the beta(+)-branching ratio. The second procedure is based on a variation of the distance between ...
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Saturday, March 29th, 2008
Effects of Electron Kinetic Energy and Ion-Electron Inelastic Collisions in Electron Capture Dissociation Measured Using Ion Nanocalorimetry.
Ion nanocalorimetry is used to measure the effects of electron kinetic energy in electron capture dissociation (ECD). With ion nanocalorimetry, the internal energy deposited into a hydrated cluster upon ...
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Saturday, March 29th, 2008
Comparative studies of (177)Lu-EDTMP and (177)Lu-DOTMP as potential agents for palliative radiotherapy of bone metastasis.
(177)Lu is presently considered as an excellent radionuclide for developing bone pain palliation agents owing to its suitable nuclear decay characteristics [T(1/2)=6.73d, E(beta)((max))=497keV, E(gamma)=113keV (6.4%) and 208keV (11%)] and large-scale production ...
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Saturday, March 29th, 2008
Optimization of sampling and counting times for gamma-ray spectrometric measurements of short-lived gamma-ray emitters in aqueous samples.
A method to determine the optimal sampling and counting regimes for water monitoring is presented. It is assumed that samples are collected at a constant rate. The collection time ...
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Saturday, March 29th, 2008
Validation study of a new technique for absolute activity measurement with 4pi solid angle metallic magnetic calorimeters.
In this paper we present a prototype of a new class of detectors, metallic magnetic calorimeters operating at cryogenic temperatures, which we are developing for absolute activity measurement of ...
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Saturday, March 29th, 2008
A remote controlled system for the preparation of 7alpha-[(18)F]fluoro-17alpha-methyl 5alpha-dihydrotestosterone ([(18)F]FMDHT) using microwave.
For non-invasive imaging of the prostate cancer, we synthesized 7alpha-fluoro-17alpha-methyl 5alpha-dihydrotestosterone ([(18)F]FMDHT) for androgen receptor mediated PET imaging. Preliminary in vitro and in vivo evaluations of this compound show promise. We designed and ...
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Saturday, March 29th, 2008
Development of a primary standard for calibration of (64)Cu activity measurement systems.
A (64)Cu national primary standard, was developed by the National Institute for Ionising Radiation Metrology (INMRI) of the ENEA (ENEA-INMRI) using the CIEMAT/NIST method of 4pibeta liquid scintillation spectrometry with (3)H-standard efficiency tracing. Relatively ...
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Saturday, March 29th, 2008
An autonomous in situ detection system for radioactivity measurements in the marine environment.
A new detection system named \"KATERINA\" is developed and applied for measuring marine radioactivity using NaI(Tl) as a crystal. This apparatus is designed for qualitative and quantitative radionuclide detection in the marine environment ...
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Saturday, March 29th, 2008
Sulfur uptake determination on Ni containing molybdena-alumina samples by radioisotope tracer technique.
Five solid oxides, used as hydrodesulfurization catalysts (Al(2)O(3) supported Ni, MoO(x), Ni-MoO(x)-s of different Ni:Mo ratio) were sulfided by [(35)S]H(2)S. Amounts of the total, reversible and irreversible sulfur uptakes were determined measuring the change ...
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Saturday, March 29th, 2008
Design and synthesis of benzofuranic derivatives as new ligands at the melatonin-binding site MT(3).
Benzofuranic analogues of MCA-NAT (5-methoxycarbonylamino-N-acetyltryptamine) have been synthesized and evaluated as melatonin receptor ligands. Introduction of a methoxycarbonylamino substituent in the C-5 position of the benzofurane nucleus obtains MT(3) selective ligands. This ...
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Saturday, March 29th, 2008
Unique combination of patellofemoral joint arthroplasty with Osteochondral Autograft Transfer System (OATS) - A case series of six knees in five patients.
Patellofemoral arthroplasty (PFA) is an accepted procedure for the treatment of isolated patellofemoral osteoarthritis. However its failure rate has been attributed to progressive femorotibial ...
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Saturday, March 29th, 2008
An epoxidation mechanism of carbamazepine by CYP3A4.
Human CYP3A4 catalyzes the 10,11-epoxidation of carbamazepine (CBZ). However, the epoxide is less stable in terms of potential energy than hydroxides of the six-membered aromatic ring. To clarify the reason why CYP3A4 produces such an energetically unfavorable compound, the ...
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Saturday, March 29th, 2008
Interactions between Myosin and Actin Crosslinkers Control Cytokinesis Contractility Dynamics and Mechanics.
INTRODUCTION: Contractile networks are fundamental to many cellular functions, particularly cytokinesis and cell motility. Contractile networks depend on myosin-II mechanochemistry to generate sliding force on the actin polymers. However, to be contractile, the networks ...
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