Archive for the ‘researches 6’ Category
Thursday, July 3rd, 2008
A New Protein Architecture for Processing Alkylation Damaged DNA: The Crystal Structure of DNA Glycosylase AlkD.
DNA glycosylases safeguard the genome by locating and excising chemically modified bases from DNA. AlkD is a recently discovered bacterial DNA glycosylase that removes positively charged methylpurines from DNA, and ...
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Thursday, July 3rd, 2008
Cytokine expression profiling of the myocardium reveals a role for CX3CL1 (fractalkine) in heart failure.
Several lines of evidence suggest that inflammatory processes mediated by cytokines are involved in the pathogenesis of heart failure (HF). However, the regulation of cytokine expression and the role of cytokines ...
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Thursday, July 3rd, 2008
Purification of Vip3Aa from Bacillus thuringiensis HD-1 and its contribution to toxicity of HD-1 to spruce budworm (Choristoneura fumiferana) and gypsy moth (Lymantria dispar) (Lepidoptera).
We developed a protocol for obtaining high yields (10-15mg per 1100ml of culture supernatant) of highly purified (up to 95%) Vip3Aa ...
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Thursday, July 3rd, 2008
Microemulsion approach to neodymium, europium, and ytterbium oxide/hydroxide colloids-Effects of precursors and preparation parameters on particle size and crystallinity.
Colloids based on lanthanides or their oxides have a great potential in the areas of optical and magnetic materials. In this study the confined space of reverse ...
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Thursday, July 3rd, 2008
Synthesis and morphological studies of nanocrystalline MOR type zeolite material.
A number of nanosize mordenite (MOR) analogues with particle size ranging from 5 to 50 nm were synthesized by the hydrothermal method. The effect of various growth parameters like: alkalinity of the medium, type of silica ...
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Thursday, July 3rd, 2008
Lithium uptake in fixed-pH solution by ion sieves.
In this study, Li(+) uptake by ion sieves was studied in a fixed-pH aqueous phase using a pH 8.0 buffer solution of ammonia/ammonium chloride. Two different spinel-type manganese oxide ion sieves were used to investigate the effect of ...
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Thursday, July 3rd, 2008
Comprehensive two-dimensional high-performance liquid chromatography system with immobilized liposome chromatography column and reversed-phase column for separation of complex traditional Chinese medicine Longdan Xiegan Decoction.
A comprehensive two-dimensional HPLC system with an immobilized liposome chromatography (ILC) column in conjunction with an RP column (in tandem) was developed ...
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Thursday, July 3rd, 2008
Qualitative and quantitative determination of the major coumarins in Zushima by high performance liquid chromatography with diode array detector and mass spectrometry.
A method, high-performance liquid chromatography coupled with diode array and electrospray tandem mass spectrometry (HPLC-DAD-ESI-MS), was developed to qualitatively identify and quantitatively determine the ...
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Thursday, July 3rd, 2008
Column chromatographic boron isotope separation at 5 and 17MPa with diluted boric acid solution.
Boron isotopic fractionation factor (S) between boron taken up in strongly basic anion exchange resin and boron in aqueous solution was determined by breakthrough column chromatography at 5 and 17MPa at 25 ...
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Thursday, July 3rd, 2008
Peak crossover in high-performance liquid chromatography elution monitored using whole-column detection.
A whole-column detection (WCD) system was fabricated using the parts from a typical A4 size optical scanner. Optimum layout of the fluorescence tube, beam condenser and photon transducers from the scanner made an effective devise ...
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Thursday, July 3rd, 2008
Superheated water chromatography on phenyl bonded hybrid stationary phases.
Phenyl bonded XTerra and XBridge organic/inorganic hybrid stationary phases have been used to separate test solutes and phenol homologues with a pure water mobile phase over a temperature range from 40 to 200 degrees C. The van\'t ...
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Thursday, July 3rd, 2008
Background vapor from six ionic liquids and the partition coefficients and limits of detection for 10 different analytes in those ionic liquids measured using headspace gas chromatography.
The concentration and identity of the compounds detected in the vapor above six ionic liquids by headspace gas chromatography ...
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Thursday, July 3rd, 2008
Assessing the significance of pedobarographic signals using random field theory.
Traditional pedobarographic statistical analyses are conducted over discrete regions. Recent studies have demonstrated that regionalization can corrupt pedobarographic field data through conflation when arbitrary dividing lines inappropriately delineate smooth field processes. An alternative is to register ...
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Thursday, July 3rd, 2008
The autoimmune origin of atherosclerosis.
Atherosclerosis is a chronic inflammatory disease. Many studies and observations suggest that it could be caused by an immune reaction against autoantigens at the endothelial level, the most relevant of which are oxidized LDL and heat shock proteins (HSP) 60/65. Endothelial ...
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Thursday, July 3rd, 2008
Uric acid: A marker of increased cardiovascular risk.
The relationship between uric acid and cardiovascular disease has been known since the 19th century, after that many authors reported the classical association of gout, hypertension, obesity and cardiovascular disease. With the exception of specific genetic defects in ...
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Thursday, July 3rd, 2008
Di-oleoyl phosphatidylcholine (PC-18:1) stimulates paraoxonase 1 (PON1) enzymatic and biological activities: In vitro and in vivo studies.
OBJECTIVE: Paraoxonase 1 (PON1) is a high-density lipoprotein (HDL)-associated enzyme which possess anti-atherogenic properties. Our aim was to analyze the effect of HDL phospholipids on HDL-associated paraoxonase (PON1) catalytic ...
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Thursday, July 3rd, 2008
PPARdelta agonist L-165041 inhibits rat vascular smooth muscle cell proliferation and migration via inhibition of cell cycle.
The peroxisome proliferator-activated receptor (PPAR) family of nuclear hormone receptors consists of three subtypes (alpha, beta/delta, and gamma). PPARdelta is ubiquitously expressed and involved in lipid and glucose metabolism. ...
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Thursday, July 3rd, 2008
Molecular basis of statin-associated myopathy.
Coronary artery disease (CAD) constitutes the most common cause of morbidity and mortality in developed countries. Statins effectively reduce low-density lipoprotein cholesterol, an important risk factor for CAD and related acute coronary syndromes. They are an extensively studied group of drugs ...
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Thursday, July 3rd, 2008
Molecular epidemiology of domestic and sylvatic Trypanosoma cruzi infection in rural northwestern Argentina.
Genetic diversity of Trypanosoma cruzi populations and parasite transmission dynamics have been well documented throughout the Americas, but few studies have been conducted in the Gran Chaco ecoregion, one of the most highly ...
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Thursday, July 3rd, 2008
Influence of a previous neck sprain on recovery after whiplash injury.
The impact of a previous neck sprain on recovery from whiplash injury is unknown as published studies have produced conflicting results. This article reviews the literature on the prognosis of a second whiplash injury, distinguishing ...
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Thursday, July 3rd, 2008
2D:4D finger-length ratios in children and adults with gender identity disorder.
Previous research suggests that prenatal testosterone affects the 2D:4D finger ratio in humans, and it has been speculated that prenatal testosterone also affects gender identity differentiation. If both things are true, then one would expect ...
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Thursday, July 3rd, 2008
Differential effects of acute progesterone administration on spatial and object memory in middle-aged and aged female C57BL/6 mice.
The present study examined the effects of acute progesterone administration on hippocampal-dependent memory consolidation in ovariectomized middle-aged (16 months old) and aged (22 months old) female mice. Spatial ...
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Thursday, July 3rd, 2008
Cervical ectopic pregnancy successfully treated with local methotrexate injection.
OBJECTIVE: To report a case where intra-amniotic injection of methotrexate (MTX) was used to terminate a cervical ectopic pregnancy that was resistant to IM MTX treatment. DESIGN: Case report. PATIENT(S): A 31-year-old woman, gravida 2, para 1, ...
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Thursday, July 3rd, 2008
Echinococcus granulosus: Induction of T-independent antibody response against protoscolex glycoconjugates in early experimental infection.
In this work CD4-knockout mice were used as a model to analyse the role of CD4(+) T cells in the antibody response against Echinococcus granulosus immunization or experimental infection. Results obtained with ...
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Thursday, July 3rd, 2008
Behavioral alterations in a mouse model of temporal lobe epilepsy induced by intrahippocampal injection of kainate.
Patients with temporal lobe epilepsy are frequently afflicted with psychiatric comorbidity and deficits in spatial and other forms of declarative memory. The relationship between epilepsy and psychopathology is poorly understood, ...
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