Archive for the ‘researches 4’ Category
Sunday, March 16th, 2008
Changes in the medial-lateral hamstring activation ratio with foot rotation during lower limb exercise.
This paper investigated whether the ratio of medial-lateral hamstring muscular activation could be altered with changes in foot rotation position (both internal and external rotation) during three standard lower limb exercises. It ...
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Sunday, March 16th, 2008
Cloning, expression, purification and characterization of recombinant glutathione-S-transferase from Xylella fastidiosa.
Xylella fastidiosa is an important pathogen bacterium transmitted by xylem-feedings leafhoppers that colonizes the xylem of plants and causes diseases on several important crops including citrus variegated chlorosis (CVC) in orange and lime trees. Glutathione-S-transferases ...
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Sunday, March 16th, 2008
Labeling, characterization, and in vivo localization of a new (90)Y-based phosphonate chelate 2,3-dicarboxypropane-1,1-diphosphonic acid for the treatment of bone metastases: Comparison with (99m)Tc-DPD complex.
The goal of this investigation was to examine the possibilities for yttrium-90-labeling of the 2,3-dicarboxypropane-1,1-diphosphonic acid (DPD), which is currently labeled with ...
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Sunday, March 16th, 2008
Tumor necrosis factor alpha mediates the lethal hepatotoxic effects of poly(I:C) in d-galactosamine-sensitized mice.
Conserved molecular patterns of microbial pathogens, such as lipopolysaccharide (LPS) and cytosine-phosphate-guanine (CpG) DNA motifs are important signals for receptor-mediated activation of innate immune cells. It has been shown that the liver-specific ...
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Sunday, March 16th, 2008
Synthesis and biological activities of 2-oxocycloalkylsulfonamides.
A series of novel 2-oxocycloalkylsulfonamides (4) were synthesized and their structures confirmed by IR, (1)H NMR, and elemental analysis. The bioassay showed that they have fair to excellent fungicidal activities against Botrytis cinerea Pers and Sclerotinia sclerotiorum. Among them, compounds ...
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Sunday, March 16th, 2008
Fluoroolefins as amide bond mimics in dipeptidyl peptidase IV inhibitors.
The synthesis, selectivity, rat pharmacokinetic profile, and drug metabolism profiles of a series of potent fluoroolefin-derived DPP-4 inhibitors (4) are reported. A radiolabeled fluoroolefin 33 was shown to possess a high propensity to form reactive metabolites, ...
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Sunday, March 16th, 2008
Is sludge retention time a decisive factor for aerobic granulation in SBR?
This study investigated the role of sludge retention time (SRT) in aerobic granulation under negligible hydraulic selection pressure. Results showed that no successful aerobic granulation was observed at the studied SRTs in the range ...
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Sunday, March 16th, 2008
Selective cell adhesion inhibitors: Barbituric acid based alpha4beta7-MAdCAM inhibitors.
A novel series of barbituric acid derivatives were identified as selective inhibitors of alpha4beta7 MAdCAM (mucosal addressin cell adhesion molecule-1) interactions via a high throughput screening exercise. These inhibitors were optimized to submicromolar potencies in whole cell ...
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Sunday, March 16th, 2008
Degradation of acetochlor by four microbial communities.
Four microbial communities capable of degrading acetochlor, designated A, D, E, and J, were obtained from acetochlor-contaminated soil and sludge. Acetochlor at an initial concentration of 55mg/L was completely degraded by the four mixed cultures after 4 days. At ...
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Sunday, March 16th, 2008
The role of earthworm Lampito mauritii (Kinberg) in amending lead and zinc treated soil.
A laboratory experiment was carried out to determine the effect of earthworm (Lampito mauritii) activity on mobility of Pb(2+) and Zn(2+) in the soil (DTPA-extractable) and its composting potential in presence of ...
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Sunday, March 16th, 2008
Changes in soil properties and in the growth of Lolium multiflorum in an acid soil amended with a solid waste from wineries.
The agronomic utility of a solid waste, waste perlite (WP), from wine companies was assessed. In this sense, the natural characteristics of the waste ...
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Sunday, March 16th, 2008
Identification and purification of the main components of cellulases from a mutant strain of Trichoderma viride T 100-14.
A new mutant strain of fungus Trichoderma viride T 100-14 was cultivated on 1% microcrystalline cellulose (Avicel) for 120h and the resulting culture filtrate was prepared for protein ...
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Sunday, March 16th, 2008
Pegylated liposomal doxorubicin-associated hand-foot syndrome: Recommendations of an international panel of experts.
BACKGROUND: Hand-foot syndrome (HFS) is dose-limiting and the most common cumulative toxicity associated with pegylated liposomal doxorubicin (PLD). It can cause considerable discomfort and lead to therapy interruption. Numerous approaches to HFS management have ...
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Sunday, March 16th, 2008
Sewage sludge ash to phosphorus fertiliser: Variables influencing heavy metal removal during thermochemical treatment.
The aim of this study was to improve the removal of heavy metals from sewage sludge ash by a thermochemical process. The resulting detoxified ash was intended for use as a raw ...
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Sunday, March 16th, 2008
Social management of LPS-induced inflammation in Formica polyctena ants.
Invertebrates, and especially insects, constitute valuable and convenient models for the study of the evolutionary roots of immune-related behaviors. With stable conditions in the nest, high population densities, and frequent interactions, social insects such as ants provide ...
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Sunday, March 16th, 2008
The role of 20-hydroxyecdysone and juvenile hormone in pupal commitment of the epidermis of the silkworm, Bombyx mori.
During the pupal metamorphosis in insects, cellular commitment for pupal differentiation must precede before its differentiation. The pupal commitment of Bombyx mori epidermis occurred from day 3 to ...
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Sunday, March 16th, 2008
Clinical significance of LAMB3 and COL7A1 mRNA in esophageal squamous cell carcinoma.
AIMS: LAMB3 and COL7A1 genes code for the laminin-5beta3 chain and type VII collagen, respectively. They constitute the major components of the basement membrane zone. The aim of the current study was to clarify ...
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Sunday, March 16th, 2008
The planetary biology of ascorbate and uric acid and their relationship with the epidemic of obesity and cardiovascular disease.
Humans have relatively low plasma ascorbate levels and high serum uric acid levels compared to most mammals due to the presence of genetic mutations in l-gulonolactone oxidase ...
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Sunday, March 16th, 2008
Antitrypsin activity of extracts from Ecballium elaterium seeds.
The antitrypsin activity of extracts obtained from two different seed types of Ecballium elaterium, was tested in vitro. The presence of trypsin inhibitors in three chromatographed samples for each extract, showed a strong and specific antitrypsin activity.
Attard E, ...
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Sunday, March 16th, 2008
Chronic hypoxia-hypercapnia influences cognitive function: A possible new model of cognitive dysfunction in chronic obstructive pulmonary disease.
Chronic obstructive pulmonary disease (COPD) is a slowly progressive lung disease that results in several complications, including cognitive dysfunction. Some evidences support that cognitive impairment is common and clinically ...
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Sunday, March 16th, 2008
Retigabine, the specific KCNQ channel opener, blocks ectopic discharges in axotomized sensory fibres.
The M-current has been proposed as a potential target for analgesia under neuropathic pain conditions. M-currents and/or their molecular correlates, KCNQ proteins, have been demonstrated in key elements of the nociceptive system including ...
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Sunday, March 16th, 2008
Carcinogenic risk of heterocyclic amines in combination - Assessment with a liver initiation model.
Carcinogenic potential of heterocyclic amines (HCAs) was investigated using an in vivo 5-week initiation assay with quantitative evaluation of glutathione S-transferase placental form (GST-P) positive foci in rat liver. Numbers of GST-P ...
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Sunday, March 16th, 2008
Genomic instability, mutations and expression analysis of the tumour suppressor genes p14(ARF), p15(INK4b), p16(INK4a) and p53 in actinic keratosis.
Actinic keratosis (AK) is a well-established pre-cancerous skin lesion that has the potential to progress to squamous cell carcinoma (SCC). We investigated the involvement of the CDKN2A, ...
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Sunday, March 16th, 2008
Factors determining copper concentration in tea leaves produced at Yuyao County, China.
Over consumption of copper (Cu) from food and beverages is detrimental to human health. In this study, we investigated Cu accumulation in tea leaves produced in Yuyao County in China. Copper concentrations in all ...
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Sunday, March 16th, 2008
Isolation and characterization of new lactam compounds that inhibit lung and colon cancer cells from adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) bran.
Five active compounds that inhibit cancer cells were isolated from adlay bran (Coix lachryma-jobi L. var. ma-yuen Stapf), and their structures and activities ...
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