Archive for the ‘researches 4’ Category
Sunday, March 16th, 2008
Expression of CAR in SW480 and HepG2 cells during G1 is associated with cell proliferation.
Constitutive androstane receptor (CAR) is a transcription factor to regulate the expression of several genes related to drug-metabolism. Here, we demonstrate that CAR protein accumulates during G1 in human SW480 and ...
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Sunday, March 16th, 2008
Short interfering RNA directed against TWIST, a novel zinc finger transcription factor, increases A549 cell sensitivity to cisplatin via MAPK/mitochondrial pathway.
Previous reports have implicated epithelial-mesenchymal transition (EMT) as a major cause of cancer. TWIST, a novel zinc finger transcription factor, was suggested to be an ...
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Sunday, March 16th, 2008
Identification of Tom5 and Tom6 in the preprotein translocase complex of human mitochondrial outer membrane.
The fungal preprotein translocase of the mitochondrial outer membrane (TOM complex) comprises import receptors Tom70, Tom20, and Tom22, import channel Tom40, and small Tom proteins Tom5, Tom6, and Tom7, which regulate ...
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Sunday, March 16th, 2008
Variant histone H2A.Z, but not the HMG proteins Nhp6a/b, is essential for the recruitment of Swi/Snf, Mediator, and SAGA to the yeast GAL1 UAS(G).
Chromatin architecture is very important for the regulation of transcriptional activation. Here, we investigated the role of two different chromatin components, the ...
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Sunday, March 16th, 2008
Membrane processes and biophysical characterization of living cells decorated with chromatic polydiacetylene vesicles.
The structural complexity of the cell membrane makes analysis of membrane processes in living cells, as compared to model membrane systems, highly challenging. Living cells decorated with surface-attached colorimetric/fluorescent polydiacetylene patches might constitute ...
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Sunday, March 16th, 2008
Redox and heavy metal effects on the biochemical activities of an Arabidopsis polyadenylation factor subunit function.
The Arabidopsis CPSF30 ortholog (AtCPSF30) is an RNA-binding endonuclease that is part of the plant polyadenylation complex. Previous work (B. Addepalli, A.G. Hunt, Nucleic Acids Res. 35 (2007) 4453-4463) demonstrated ...
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Sunday, March 16th, 2008
Phosphorylation-dependent regulation of excitation energy distribution between the two photosystems in higher plants.
Phosphorylation-dependent movement of the light-harvesting complex II (LHCII) between photosystem II (PSII) and photosystem I (PSI) takes place in order to balance the function of the two photosystems. Traditionally, the phosphorylatable fraction of ...
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Sunday, March 16th, 2008
Transcription factors controlling osteoblastogenesis.
The recent development of molecular biology and mouse genetics and the analysis of the skeletal phenotype induced by genetic mutations in humans led to a better understanding of the role of transcription factors that govern bone formation. This review summarizes the role ...
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Sunday, March 16th, 2008
Dynamic mechanical behavior of starch-based scaffolds in dry and physiologically simulated conditions: Effect of porosity and pore size.
The three-dimensional scaffolds of a blend of starch and poly(l-lactic) acid, SPLA70, were produced using compression molding of polymer/salt mixture followed by leaching of salt. One series of ...
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Sunday, March 16th, 2008
Automatic detection of immature platelets for decision making regarding platelet transfusion indications for pediatric patients.
Immature or reticulated platelets are known as a clinical marker of thrombopoiesis. Recently, an automatic method was established to detect reticulated platelets as immature platelet fraction (IPF) by means of hematology ...
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Sunday, March 16th, 2008
Efficacy, tolerability, and side effects of oxcarbazepine monotherapy: A prospective study in adult and elderly patients with newly diagnosed partial epilepsy.
OBJECTIVE: The aim of the study described here was to investigate the efficacy, tolerability, and side effects of oxcarbazepine (OXC) monotherapy in newly diagnosed, previously ...
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Sunday, March 16th, 2008
Therapeutic plasma exchange in patients with neurologic diseases: Retrospective multicenter study.
Therapeutic plasma exchange (TPE) is commonly used in many neurological disorders where an immune etiology was known or suspected. We report our experience with TPE performed for neuroimmunologic disorders at four university hospitals. The study ...
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Sunday, March 16th, 2008
EEG power and coherence in autistic spectrum disorder.
OBJECTIVE: Autistic spectrum disorder (ASD) has been defined as a neurodevelopmental disorder with associated deficits in executive function, language, emotional, and social function. ASD has been associated with pathophysiology in cerebral organization. The current study investigated quantitative EEG ...
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Sunday, March 16th, 2008
Re-donation intentions among experienced blood donors: Does gender make a difference?
Path analysis was used to examine sex differences in motivation for repeat donation among experienced blood donors. Results confirm the importance of constructs from the Theory of Planned Behavior (e.g., donation attitude, subjective norm, personal ...
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Sunday, March 16th, 2008
Brain perfusion abnormalities in a sibship with parkin-linked parkinsonism.
We demonstrated brain perfusion abnormalities in a sibship with parkin-linked parkinsonism. The sibship consisted of a 64-year-old man and a 62-year-old woman. Both patients had homozygous deletions of exon 4 in the parkin gene. Hypoperfusion in the ...
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Sunday, March 16th, 2008
Studies in use of the Greulich-Pyle skeletal age method to assess criminal liability.
In recent years, skeletal age determination has become increasingly important for determining the age of live subjects as part of criminal investigation. The most widely used method worldwide to determine skeletal age is ...
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Sunday, March 16th, 2008
Technical approaches to the optimisation of CT.
This paper reviews current technical approaches to the optimisation of CT practice, i.e. approaches to reduce patient dose to the necessary minimum. The most important step towards this goal appears to be the technology of tube current modulation (TCM), ...
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Sunday, March 16th, 2008
Dynamic heart phantom for the quality control of SPECT equipment.
A nuclear imaging of heart is a noninvasive procedure that reveals the cardiac structure and physiology enabling evaluation of cardiac function. According to the regulations published by the Polish Government and the Polish Ministry of Health, ...
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Sunday, March 16th, 2008
Transaldolase deficiency in a two-year-old boy with cirrhosis.
Transaldolase (TALDO) deficiency is a rare inborn error of the pentose phosphate pathway. We report the clinical presentation and laboratory findings of a new patient with TALDO deficiency. The two-year-old Arabic boy presented with neonatal onset of anemia ...
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Sunday, March 16th, 2008
Interaction between anxiety, depression, quality of life and clinical parameters in chronic tension-type headache.
Our aim was to investigate the mediating or moderating role of anxiety and depression in the relationship between headache clinical parameters and quality of life in Chronic Tension-Type Headache (CTTH). Twenty-five patients ...
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Sunday, March 16th, 2008
Differential gene expression induced by growth hormone treatment in the uremic rat growth plate.
OBJECTIVES: Treatment with growth hormone (GH) improves growth retardation of chronic renal failure. cDNA microarrays were used to investigate GH-induced modifications in gene expression in the tibial growth plate of young rats. ...
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Sunday, March 16th, 2008
Chronic, but not acute, tricyclic antidepressant treatment alleviates neuropathic allodynia after sciatic nerve cuffing in mice.
Antidepressant drugs act mainly by blocking the noradrenaline and/or serotonin uptake sites and require a chronic treatment. Tricyclic antidepressants are among the first line treatments clinically recommended against neuropathic pain. ...
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Sunday, March 16th, 2008
Effects of moderate chronic ethanol consumption on hippocampal nicotinic receptors and associative learning.
A number of studies have reported that ethanol exposure induces changes in different brain systems. The hippocampus is a brain region that is very vulnerable to ethanol exposition, which functionally results in impairment ...
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Sunday, March 16th, 2008
Neural correlates of subliminal and supraliminal letter processing-An event-related fMRI study.
One problem of interpreting research on subconscious processing is the possibility that participants are weakly conscious of the stimuli. Here, we compared the fMRI BOLD response in healthy adults to clearly visible single letters (supraliminal ...
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Sunday, March 16th, 2008
Reproductive isolation among cryptic species in the ectomycorrhizal genus Strobilomyces: Population-level CAPS marker-based genetic analysis.
Among the higher fungi, reproductively isolated cryptic species exist that are morphologically difficult to distinguish owing to a lack of taxonomically useful morphological characters. Mating tests are helpful for detecting reproductive ...
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