Archive for the ‘researches 4’ Category
Sunday, March 16th, 2008
Two mosaic terminal inverted duplications arising post-zygotically: evidence for possible formation of neo-telomeres.
ABSTRACT: OBJECTIVE: To elucidate the structure of terminal inverted duplications and to investigate potential mechanisms of formation in two cases where there was mosaicism with cells of apparently normal karyotype. RESULTS: A karyotype ...
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Sunday, March 16th, 2008
Obsessive compulsive disorder comorbidity in DBA.
ABSTRACT: Diamond-Blackfan Anemia (DBA) is a congenital erythroid aplasia characterized as a normochromic macrocytic anemia with a selective deficiency in red blood cell precursors in otherwise normocelullar bone marrow. DBA is known to be associated with mental retardation and learning ...
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Sunday, March 16th, 2008
Salmon louse (Lepeophtheirus salmonis) transcriptomes during post molting maturation and egg production, revealed using EST-sequencing and microarray analysis.
ABSTRACT: BACKGROUND: Lepeophtheirus salmonis is an ectoparasitic copepod feeding on skin, mucus and blood from salmonid hosts. Initial analysis of EST sequences from pre adult and adult stages ...
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Sunday, March 16th, 2008
Analyzing stochastic transcription to elucidate the nucleoid\'s organization.
ABSTRACT: BACKGROUND: The processes of gene transcription, translation, as well as the reactions taking place between gene products, are subject to stochastic fluctuations. These stochastic events are being increasingly examined as it emerges that they can be crucial ...
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Sunday, March 16th, 2008
Psychological drivers in doping: the life-cycle model of performance enhancement.
ABSTRACT: BACKGROUND: Performance enhancement (PE) is a natural and essential ingredient of competitive sport. Except for nutritional supplement contamination, accidental use of doping is highly unlikely. It requires deliberation, planning and commitment; and is influenced by ...
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Sunday, March 16th, 2008
The Involvement of Bax in Zinc-Induced Mitochondrial Apoptogenesis in Malignant Prostate Cells.
ABSTRACT: BACKGROUND: The development and progression of prostate cancer requires the transformation of normal zinc-accumulating epithelial cells to malignant cells that have lost the ability to accumulate zinc. This metabolic transformation is essential so ...
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Sunday, March 16th, 2008
A quantitative method for determining spatial discriminative capacity.
ABSTRACT: BACKGROUND: The traditional two-point discrimination (TPD) test, a widely used tactile spatial acuity measure, has been criticized as being imprecise because it is based on subjective criteria and involves a number of non-spatial cues. The results of ...
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Sunday, March 16th, 2008
Correlating corneal arcus with atherosclerosis in familial hypercholesterolemia.
ABSTRACT: BACKGROUND: A relationship between corneal arcus and atherosclerosis has long been suspected but is controversial. The homozygous familial hypercholesterolemia patients in this study present a unique opportunity to assess this issue. They have both advanced atherosclerosis and ...
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Sunday, March 16th, 2008
Can subtle changes in gene expression be consistently detected with different microarray platforms?
ABSTRACT: BACKGROUND: The comparability of gene expression data generated with different microarray platforms is still a matter of concern. Here we address the performance and the overlap in the detection of differentially expressed ...
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Sunday, March 16th, 2008
Treatment of experimental colitis in mice with LMP-420, an inhibitor of TNF transcription.
ABSTRACT: BACKGROUND: LMP-420 is a boronic acid-containing purine nucleoside analogue that transcriptionally inhibits TNF production but is non-cytotoxic to TNF-producing cells. METHODS: This study investigated the efficacy of LMP-420 as an anti-inflammatory agent ...
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Sunday, March 16th, 2008
Comprehensive analysis of NuMA variation in breast cancer.
ABSTRACT: BACKGROUND: A recent genome wide case-control association study identified NuMA region on 11q13 as a candidate locus for breast cancer susceptibility. Specifically, the variant Ala794Gly was suggested to be associated with increased risk of breast cancer. METHODS: ...
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Sunday, March 16th, 2008
Analysis of oral cancer epidemiology in the US reveals state-specific trends: implications for oral cancer prevention.
ABSTRACT: BACKGROUND: Downward trends have been observed in oral cancer incidence and mortality in the US over the past 30 years; however, these declines are not uniform within this population. ...
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Sunday, March 16th, 2008
Migration of Superior Vena Cava Stent.
ABSTRACT: There has been a recent increase in the use of endovascular prostheses resulting in complex surgical and interventional complications not previously recognised. We report a case of Superior vena cava stenosis treated with a Wallstent which migrated to the ...
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Sunday, March 16th, 2008
Functionally important segments in proteins dissected using Gene Ontology and geometric clustering of peptide fragments.
ABSTRACT: We have developed a geometric clustering algorithm using backbone phi,psi angles to group conformationally similar peptide fragments of any length. By labelling each fragment in the cluster with level-specific Gene ...
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Sunday, March 16th, 2008
Transcriptomic analysis of the dialogue between Pseudorabies virus and porcine epithelial cells during infection.
ABSTRACT: BACKGROUND: Transcriptomic approaches are relevant for studying virus-host cell dialogues to better understand the physiopathology of infection and the immune response at the cellular level. Pseudorabies virus (PrV), a porcine Alphaherpesvirus, ...
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Sunday, March 16th, 2008
Adrenergic gene polymorphisms and cardiovascular risk in the NHLBI-sponsored Women\'s Ischemia Syndrome Evaluation.
ABSTRACT: BACKGROUND: Adrenergic gene polymorphisms are associated with cardiovascular and metabolic phenotypes. We investigated the influence of adrenergic gene polymorphisms on cardiovascular risk in women with suspected myocardial ischemia. METHODS: We genotyped 628 ...
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Sunday, March 16th, 2008
Gene expression analysis of the ovary of hybrid females of Xenopus laevis and X. muelleri.
ABSTRACT: BACKGROUND: Interspecific hybrids of frogs of the genus Xenopus result in sterile hybrid males and fertile hybrid females. Previous work has demonstrated a dramatic asymmetrical pattern of misexpression in hybrid ...
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Sunday, March 16th, 2008
The use of botulinum toxin in head and face medicine: an interdisciplinary field.
ABSTRACT: BACKGROUND: In this review article different interdisciplinary relevant applications of botulinum toxin type A (BTA) in the head and face region are demonstrated. Patients with head and face disorders of different etiology ...
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Sunday, March 16th, 2008
Intratracheal dopamine attenuates pulmonary edema and improves survival after ventilator-induced lung injury in rats.
ABSTRACT: BACKGROUND: Clearance of alveolar edema depends on active transport of sodium across the alveolar epithelial barrier. Beta-adrenergic agonists increase pulmonary edema clearance, but it has not been established whether beta agonist ...
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Sunday, March 16th, 2008
Beyond satisfaction: Using the Dynamics of Care assessment to better understand patients\' experiences in care.
ABSTRACT: BACKGROUND: Patient perceptions of and satisfaction with care have become important indicators of the quality of services and the relationship of services to treatment outcomes. However, assessment of these indicators ...
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Sunday, March 16th, 2008
The burden of disease profile of residents of Nairobi\'s slums: Results from a Demographic Surveillance System.
ABSTRACT: BACKGROUND: With increasing urbanization in sub-Saharan Africa and poor economic performance, the growth of slums is unavoidable. About 71% of urban residents in Kenya live in slums. Slums are ...
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Sunday, March 16th, 2008
Computational identification of obligatorily autocatalytic replicators embedded in metabolic networks.
ABSTRACT: BACKGROUND: If chemical A is necessary for the synthesis of more chemical A then A has the power of replication (such systems are known as autocatalytic systems). We provide the first systems-level analysis to search ...
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Sunday, March 16th, 2008
Malnutrition and bilateral central retinal vein occlusion in a young woman: a case report.
ABSTRACT: INTRODUCTION: Can vitamin B12 and folate deficiency cause central retinal vein occlusion? We conducted a literature search to find out whether nutritional deficiency of vitamin B12 and folate can lead to ...
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Sunday, March 16th, 2008
Crucial role of zebrafish prox1 in hypothalamic catecholaminergic neurons development.
ABSTRACT: BACKGROUND: Prox1, the vertebrate homolog of prospero in Drosophila melanogaster, is a divergent homeogene that regulates cell proliferation, fate determination and differentiation during vertebrate embryonic development. RESULTS: Here we report that, in zebrafish, prox1 is ...
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Sunday, March 16th, 2008
Maternal care in rural China: a case study from Anhui province.
ABSTRACT: BACKGROUND: Studies on prenatal care in China have focused on the timing and frequency of prenatal care and relatively little information can be found on how maternal care has been organized and funded or ...
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