Archive for the ‘for377cat’ Category
Friday, June 27th, 2008
Spatial analysis of the etiology of amyotrophic lateral sclerosis among 1991 Gulf War veterans.
BACKGROUND: Veterans of the 1991 Gulf War have an increased risk of amyotrophic lateral sclerosis (ALS), but the etiology is unknown. OBJECTIVES: This study sought to identify geographic areas with elevated risk ...
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Friday, June 27th, 2008
Central 5-HT receptors in cardiovascular control during stress.
Our aim is to consolidate recent data on relationship between central serotonergic neurotransmission and stress-elicited cardiovascular changes. Activation of central of 5-HT1A receptors attenuates tachycardic and pressor changes elicited by a wide range of stressors (airjet, restraint, open ...
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Friday, June 27th, 2008
Modafinil decreases food intake in humans subjected to simulated shift work.
In a limited number of studies modafinil has been shown to decrease food intake by laboratory animals and humans. The present study represents a secondary data analysis, in which the effects of modafinil on several ...
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Friday, June 27th, 2008
Toxin-screening and identification of bacteria isolated from highly toxic marine gastropod Nassarius semiplicatus.
Bacteria isolated from a highly toxic sample of gastropod Nassarius semiplicatus in Lianyungang, Jiangsu Province in July 2007, were studied to probe into the relationship between bacteria and toxicity of nassariid gastropod. The ...
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Friday, June 27th, 2008
First report on azaspiracid and yessotoxin groups detection in French shellfish.
The French Phytoplankton and Phycotoxins monitoring network (REPHY) recently found positive or dubious negative shellfish samples using lipophilic toxins mouse bioassay. These samples were analyzed by liquid chromatography (LC) in combination with mass spectrometry (MS) ...
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Friday, June 27th, 2008
Proteomic analysis of the honey bee worker venom gland focusing on the mechanisms of protection against tissue damage.
Honey bee workers use venom for the defence of the colony and themselves when they are exposed to dangers and predators. It is produced by a long thin, ...
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Friday, June 27th, 2008
Aged-related toxic effects and recovery from okadaic acid treatment in Enchytraeus crypticus (Annelida: Oligochaeta).
The effects of 48h okadaic acid (OA) treatment and the ability to recover the induced toxicological injuries were examined in Enchytraeus crypticus of different ages (25 days and 3 months). The results ...
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Friday, June 27th, 2008
Bacterial degradation of paralytic shellfish toxins.
Bacteria isolated from the digestive tracts of blue mussels (Mytilus edulis) contaminated with paralytic shellfish toxins (PSTs) were screened for the ability to reduce the toxicity of a PST mixture in vitro. Bacteria were isolated on marine agar and grown ...
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Friday, June 27th, 2008
Radicicol improves regeneration of skeletal muscle previously damaged by crotoxin in mice.
This work investigates the influence of heat shock proteins (HSPs) on necrosis and subsequent skeletal muscle regeneration induced by crotoxin (CTX), the major component of Crotalus durissus terrificus venom. Mice were treated with radicicol, ...
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Friday, June 27th, 2008
Developmental neurotoxicity of Propylthiouracil (PTU) in rats: Relationship between transient hypothyroxinemia during development and long-lasting behavioural and functional changes.
Markedly lowered thyroid hormone levels during development may influence a child\'s behaviour, intellect, and auditory function. Recent studies, indicating that even small changes in the mother\'s thyroid ...
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Friday, June 27th, 2008
Variable expression of 11beta Hydroxysteroid dehydrogenase (11beta-HSD) isoforms in vascular endothelial cells.
Vascular tissue expresses two isoforms of the enzyme 11beta-Hydroxysteroid dehydrogenase, 11beta-HSD1 and 11beta-HSD2. These enzymes are responsible for the local metabolism of endogenous glucocorticoids (GCs). 11beta-HSD1 deactivates GCs to their 11keto metabolites or transforms ...
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Friday, June 27th, 2008
Who caused the pain? An fMRI investigation of empathy and intentionality in children.
When we perceive other people in pain, the neural circuits underpinning the processing of first-hand experience of pain are activated in the observer. This basic somatic sensorimotor resonance plays a critical role in ...
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Friday, June 27th, 2008
A neuroprotective agent, T-817MA (1-{3-[2-(1-benzothiophen-5-yl)ethoxy]propyl}-3-azetidinol maleate), prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice.
T-817MA (1-{3-[2-(1-benzothiophen-5-yl)ethoxy]propyl}-3-azetidinol maleate) is a candidate therapeutic agent for Alzheimer\'s disease that inhibits oxidative stress and nitric oxide-induced neurotoxicity and acts as a neurotrophic factor. The present study examines the effect of T-817MA on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine ...
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Friday, June 27th, 2008
Conditioning-strength dependent involvement of NMDA NR2B subtype receptor in the basolateral nucleus of amygdala in acquisition of auditory fear memory.
It is known that N-methyl-d-aspartate (NMDA) receptor in the basolateral nucleus of amygdala (BLA) is essential for fear memory formation. NMDA NR2B and NR2A subtype receptors ...
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Friday, June 27th, 2008
The cost of cerebral ischaemia.
Cerebral ischaemia is a major cause of disability and death globally and has a profoundly negative impact on the individuals it affects, those that care for them and society as a whole. The most common and familiar manifestation is stroke, 85% ...
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Friday, June 27th, 2008
Lethal pathogens, non-lethal synergists and the evolutionary ecology of resistance.
Mixed pathogenic infections are known to have profound effects on the ecological and evolutionary diversity of both hosts and parasites. Although a variety of mechanisms have been proposed by which hosts can withstand parasitic infections, the ...
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Friday, June 27th, 2008
The effects of distributed life cycles on the dynamics of viral infections.
We explore the role of cellular life cycles for viruses and host cells in an infection process. For this purpose, we derive a generalized version of the basic model of virus dynamics (Nowak, M.A., ...
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Friday, June 27th, 2008
Myosin binding protein C phosphorylation in normal, hypertrophic and failing human heart muscle.
Phosphorylation of myosin binding protein C (MyBP-C) was investigated in intraventricular septum samples taken from patients with hypertrophic cardiomyopathy undergoing surgical septal myectomy. These samples were compared with donor heart muscle, as a ...
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Friday, June 27th, 2008
Differential mechanisms of angiotensin II and PDGF-BB on migration and proliferation of coronary artery smooth muscle cells.
Angiotensin II (Ang II) and platelet-derived growth factor-BB (PDGF-BB) are associated with excessive cell migration, proliferation and many growth-related diseases. However, whether these agents utilise similar mechanisms to trigger ...
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Friday, June 27th, 2008
Distribution of Paenibacillus larvae spores inside honey bee colonies and the possibilities for diagnosis.
One of the most important factors affecting the development of honey bee colonies is infectious diseases such as American foulbrood (AFB) caused by the spore forming Gram-positive bacterium Paenibacillus larvae. Colony inspections ...
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Friday, June 27th, 2008
Stochastic induction of Theileria annulata merogony in vitro by chloramphenicol.
Theileria annulata inhabits the cytoplasm of bovine leukocytes where it can be found as a multinucleated schizont. The schizont is the pathogenic stage of the life cycle and by interfering with host signalling pathways, it induces ...
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Friday, June 27th, 2008
Sex-related changes in estrogen receptors and aromatase gene expression and enzymatic activity during early development and sex differentiation in the European sea bass (Dicentrarchus labrax).
The present study addresses the role of aromatase and estrogen receptors in sex differentiation and development. With this purpose, a sea ...
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Friday, June 27th, 2008
Self-recognition by an intrinsically disordered protein.
The intrinsically disordered translocation domain (T-domain) of the protein antibiotic colicin N binds to periplasmic receptors of target Escherichia coli cells in order to penetrate their inner membranes. We report here that the specific 27 consecutive residues of the T-domain ...
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Friday, June 27th, 2008
Regulation of the human tRNase Z(S) gene expression.
There are two types of tRNA 3\' processing endoribonucleases (tRNase Z): a short form (tRNase Z(S)) and a long form (tRNase Z(L)). Although the human genome contains both genes, little is known about the physiological role of tRNase ...
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Friday, June 27th, 2008
Serpins show structural basis for oligomer toxicity and amyloid ubiquity.
Many disorders, including Alzheimer\'s, the prion encephalopathies and other neurodegenerative diseases, result from aberrant protein aggregation. Surprisingly, cellular toxicity is often due not to the highly-ordered aggregates but to the oligomers that precede their formation. Using ...
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