Archive for the ‘for377cat’ Category
Friday, June 27th, 2008
Microbiological characterization of table olives commercialized in Portugal in respect to safety aspects.
Table olives are a traditional component of the Mediterranean diet and are largely consumed in the world. There are different trade treatments that originate different types of olives. The aim of the present ...
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Friday, June 27th, 2008
Charcoal emissions as a source of CO and carcinogenic PAH in mainstream narghile waterpipe smoke.
Burning charcoal is normally placed atop the tobacco to smoke the narghile waterpipe. We investigated the importance of charcoal as a toxicant source in the mainstream smoke, with particular attention to ...
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Friday, June 27th, 2008
No pituitary gland volume change in medication-free depressed patients.
Increased serum cortisol levels and a hyperactive hypothalamo-pituitary-adrenal (HPA) axis have been proposed to play an important role in the pathophysiology of Major Depressive Disorder (MDD). However, there are inconsistent results regarding pituitary gland volume (PGV), which ...
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Friday, June 27th, 2008
Effects of antidepressants on mRNA levels of antioxidant enzymes in human monocytic U-937 cells.
Alterations of antioxidant enzyme activities have been described in a number of psychiatric disorders including major depression. Subsequently, the present study examined the effects of different types of antidepressants (desipramine, imipramine, maprotiline ...
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Friday, June 27th, 2008
Preclinical assessment of the receptor-binding domain of Plasmodium vivax Duffy-binding protein as a vaccine candidate in rhesus macaques.
The receptor-binding domain of Plasmodium vivax Duffy-binding protein, region II (PvRII), is an attractive candidate for a vaccine against P. vivax malaria. Here, we have studied the safety ...
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Friday, June 27th, 2008
Ecological fallacy and scepticism about influenza vaccine efficacy in Japan: The Maebashi Study.
In 1979, Maebashi City discontinued influenza mass vaccination immediately after a case of vaccine-related convulsion occurred. A research group of the Maebashi City Medical Association studied the effects of mass vaccination on influenza ...
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Friday, June 27th, 2008
The effect of misclassification on evaluating the effectiveness of influenza vaccines.
Misclassification is a measurement error and can be considered a type of information bias. Misclassification can occur at both exposure and outcome levels. Nondifferential misclassification causes only a dilution effect leading to underestimation, whereas differential ...
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Friday, June 27th, 2008
Influenza vaccine effectiveness among elderly persons living in the community during the 2003-2004 season.
To examine the effectiveness of influenza vaccine among community-dwelling elderly (65-79 years old), we conducted a population-based cohort study during the 2003-2004 influenza season. A total of 4787 elderly individuals were interviewed ...
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Friday, June 27th, 2008
Confounding in evaluating the effectiveness of influenza vaccine.
Confounding is a kind of bias which occurs in a research. Confounding is less frequent in randomized controlled trials (RCT) for evaluation of influenza vaccines. However, there are obstacles or difficulties in conducting RCT for evaluation of influenza ...
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Friday, June 27th, 2008
Influenza vaccine effectiveness and confounding factors among young children.
This study, done during the 2002-2003 season among children <6 years of age to investigate influenza vaccine effectiveness and confounding factors, involved 2913 children (1512 vaccinees, 1401 non-vaccinees) recruited from 54 paediatric clinics. Between December 2002 and ...
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Friday, June 27th, 2008
History of influenza vaccination programs in Japan: Prologue to the symposium.
In 1976, influenza mass vaccination among schoolchildren was started under the Preventive Vaccination Law, which was intended to control epidemics in the community. However, in the late 1980s, questions about this policy and vaccine efficacy ...
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Friday, June 27th, 2008
Essential tools for assessing influenza vaccine efficacy in improperly conducted studies: A Japanese perspective.
The fundamental issue in assessing influenza vaccine efficacy is to observe all study subjects with equal intensity throughout the surveillance period. The case definition can be adopted within the scope of the ...
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Friday, June 27th, 2008
Pathogenicity and immunogenicity of recombinant Tiantan Vaccinia Virus with deleted C12L and A53R genes.
Interest is increasing regarding replicating poxvirus as HIV vaccine vector. In China, the Tiantan Vaccinia Virus (TV) has been used most extensively in the battle of eradicating smallpox. Recently, TV was developing ...
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Friday, June 27th, 2008
Ecological studies on influenza infection and the effect of vaccination: Their advantages and limitations.
Ecological studies lack the ability to control for the effects of confounding factors. The findings of a linear relationship between average exposure and disease frequency in ecological studies do not imply that ...
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Friday, June 27th, 2008
Relationship between soluble HLA-G and HLA-A,-B,-C serum levels, and interferon-gamma production after sublingual immunotherapy in patients with allergic rhinitis.
Allergic rhinitis (AR) is characterized by a T-helper (Th)-2 (Th2) polarized immune response. Soluble human leukocyte antigen (sHLA) molecules play an immunomodulatory role. Specific immunotherapy is the ...
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Friday, June 27th, 2008
The GlxR regulon of the amino acid producer Corynebacterium glutamicum: In silico and in vitro detection of DNA binding sites of a global transcription regulator.
The glxR (cg0350) gene of Corynebacterium glutamicum ATCC 13032 encodes a DNA-binding trancription regulator of the CRP/FNR protein family. Five genomic ...
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Friday, June 27th, 2008
Rapid fluorescent assay for screening drugs on Leishmania amastigotes.
A rapid fluorescent viability assay employing alamarBlue was optimized for use with Leishmania axenic amastigotes, the stage of the parasite responsible for disease pathology. The activity of two protein kinase inhibitors, Staurosporine and H-89, as well as ...
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Friday, June 27th, 2008
Caveolae are an essential component of the pathway for endothelial cell signaling associated with abrupt reduction of shear stress.
Abrupt cessation of flow representing the acute loss of shear stress (simulated ischemia) to flow-adapted pulmonary microvascular endothelial cells (PMVEC) leads to reactive oxygen species (ROS) generation ...
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Friday, June 27th, 2008
Overexpression of functional TrkA receptors after internalisation in human airway smooth muscle cells.
Trafficking of the TrkA receptor after stimulation by NGF is of emerging importance in structural cells in the context of airway inflammatory diseases. We have recently reported the expression of functional TrkA receptors ...
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Friday, June 27th, 2008
IL-6 induces MUC4 expression through gp130/STAT3 pathway in gastric cancer cell lines.
The gastric mucosal levels of the pro-inflammatory cytokine Interleukin 6 (IL-6) have been reported to be increased in Helicobacter pylori-infected subjects and, in gastric adenocarcinomas, the up-regulation of intestinal mucin genes (MUC2 and MUC4) ...
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Friday, June 27th, 2008
Supramolecular organization of protein complexes in the mitochondrial inner membrane.
The liquid state model that envisions respiratory chain complexes diffusing freely in the membrane is increasingly challenged by reports of supramolecular organization of the complexes in the mitochondrial inner membrane. Supercomplexes of complex III with complex ...
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Friday, June 27th, 2008
Anxiety-like behavior during nicotine withdrawal predict subsequent nicotine consumption in adolescent C57BL/6 mice.
We have previously demonstrated that anxiety-like behavior assessed in the elevated plus maze does not predict subsequent nicotine consumption in naïve adolescent mice. However, an association between anxiety and relapse to drug use ...
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Friday, June 27th, 2008
Intramuscularly administered neuraminidase inhibitor peramivir is effective against lethal H5N1 influenza virus in mice.
The replication efficiency and multi-organ dissemination of some influenza A (H5N1) viruses requires a rapid (re)evaluation of the available antiviral strategies. We assessed five regimens of the neuraminidase (NA) inhibitor peramivir in ...
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Friday, June 27th, 2008
Effect of an immune enhancer, GPI-0100, on vaccination with live attenuated herpes simplex virus (HSV) type 2 or glycoprotein D on genital HSV-2 infections of guinea pigs.
These studies were performed to determine the effect of AD-472, an attenuated human herpes simplex virus (HSV) type 2 ...
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Friday, June 27th, 2008
CD5 plays an inhibitory role in the suppressive function of murine CD4(+) CD25(+) T(reg) cells.
A subset of CD4(+) T cells, the CD4(+) CD25(+) regulatory T (T(reg)) cells in the lymphoid organs and peripheral blood are known to possess suppressive function. Previous in vitro and in ...
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