Ultrafast Reversible Photo-Cross-Linking Reaction: Toward in Situ DNA Manipulation.
June 29th, 2008 | by admin |Ultrafast Reversible Photo-Cross-Linking Reaction: Toward in Situ DNA Manipulation.
We describe a novel ultrafast reversible DNA interstrand photo-cross-linking reaction via 3-cyanovinylcarbazole nucleoside ( (CNV)K). Oligodeoxynucleotide (ODN) containing (CNV)K can be photo-cross-linked by irradiation at 366 nm for 1 s, and the photo-cross-linked ODN can be split by irradiation at 312 nm for 60 s.
Yoshimura Y, Fujimoto K.