The missing niche for spermatogonial stem cells: do blood vessels point the way?
March 29th, 2008 | by admin |The missing niche for spermatogonial stem cells: do blood vessels point the way?
Although spermatogonial stem cell niches have been defined in lower organisms, their definitive localization in mammalian seminiferous tubules has been elusive. In a recent Science paper, Yoshida et al. (2007) elegantly demonstrated a vascular and interstitial tissue-associated niche for undifferentiated spermatogonia in the mouse.
Shetty G, Meistrich ML.
Department of Experimental Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.