Synthesis and cytotoxicity of aurilide analogs.

June 29th, 2008 | by admin |

Synthesis and cytotoxicity of aurilide analogs.

The artificial analogs of aurilide (1), a potent cytotoxic cyclodepsipeptide of marine origin, were synthesized, and the structure-activity relationships were investigated.

Suenaga K, Kajiwara S, Kuribayashi S, Handa T, Kigoshi H.

Department of Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku, Yokohama 223-8522, Japan.

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