Organozinc Reagents in DMSO Solvent: Remarkable Promotion of SN2′ Reaction for Allene Synthesis.
June 29th, 2008 | by admin |Organozinc Reagents in DMSO Solvent: Remarkable Promotion of SN2\’ Reaction for Allene Synthesis.
The S N2\’ reaction of propragyl mesylates with organozinc reagents was dramatically improved in DMSO solvent, and the stereoselective conversion of chiral substrates was successfully achieved using LiCl-free diorganozinc without the loss of optical purity.
Kobayashi K, Naka H, Wheatley AE, Kondo Y.