One-Pot Synthesis of Cyclic Triamides with a Triangular Cavity from trans-Stilbene and Diphenylacety
June 29th, 2008 | by admin |One-Pot Synthesis of Cyclic Triamides with a Triangular Cavity from trans-Stilbene and Diphenylacetylene Monomers.
Base-promoted self-condensation reactions of trans-stilbene and diphenylacetylene monomers bearing 4-alkylamino and 4\’-methoxycarbonyl groups were investigated. Reactions of N-propyl monomers under pseudohigh-dilution conditions (a THF solution of monomer was added dropwise to a THF solution of LiHMDS) afforded the corresponding cyclic triamides in good yields. X-ray crystallographic analysis showed that these cyclic triamides possessed an almost equilateral triangle structure with a cavity surrounded by tilted benzene rings.
Yokoyama A, Maruyama T, Tagami K, Masu H, Katagiri K, Azumaya I, Yokozawa T.