Near-infrared spectroscopy study of language activated hyper- and hypo-oxygenation in human prefront
May 1st, 2008 | by admin |Near-infrared spectroscopy study of language activated hyper- and hypo-oxygenation in human prefrontal cortex.
Oxygenation changes in the left prefrontal cortex during language processing were assessed with near-infrared spectroscopy (NIRS). Oxyhemoglobin and deoxyhemoglobin concentrations at the Fp1 site during 5 min of resting with eyes closed (control), followed by 5 min of reading aloud, were monitored. A statistically significant change in the oxyhemoglobin concentration was observed by NIRS in all the subjects after execution of the experimental task. The observations of hyper-oxygenation as well as hypo-oxygenation in the present investigation extend past studies and suggest a complex phenomenon of activation that may be the result of a vascular steal mechanism, attenuated activation baselines, or active cortical deactivation.
Liu KR, Borrett DS, Cheng A, Gasparro D, Kwan HC.
Department of Physiology, Medical Sciences Building University of Toronto, Toronto, Ontario, Canada.